Latest News Archive

Please select Category, Year, and then Month to display items
Previous Archive
21 June 2021 Photo Supplied
Carmien Tolmie
Dr Carmien Tolmie says being involved in the Global Challenges Research Fund (GCRF) START grant over the past three years has made a very concrete contribution to her career as a young scientist.

Dr Carmien Tolmie – Lecturer in the Department of Microbiology and Biochemistry at the University of the Free State (UFS) – is one of 30 postdoctoral research assistants in the United Kingdom and Africa who have benefited from the £3,7 M Global Challenges Research Fund (GCRF) START grant over the past three years. The grant was made available by the Science and Technology Facilities Council (STFC) in support of the Synchrotron Techniques for African Research and Technology (START) programme. The STFC is based in the United Kingdom.

The grant seeks to build partnerships between world-leading scientists in Africa and the UK who are working on research using synchrotron science. Forming part of this collaboration is the UK’s national synchrotron, Diamond Light Source (Diamond). The synchrotron, one of about 70 in the world, can be explained as a large machine, almost the size of a football field, which accelerates electrons to nearly the speed of light. According to Diamond, these fast-moving electrons produce very bright light, called synchrotron light. Scientists can use this light to study minute matter such as atoms and molecules.

 

Celebrating a new generation of scientists

On 7 June 2021, GCRF START celebrated its successes of the past years via a virtual event, including the new generation of scientists they trained. Diamond Light Source (Diamond) hosted the event.

In a statement issued by Diamond Light Source, Dr Tolmie was said to be one of the rising stars in the newly emerging Structural Biology network in South Africa. The statement reads that Dr Tolmie has made great strides with biocatalysis, investigating enzymes as drug targets for fungal infectious diseases that claim many lives, especially among immunocompromised patients.

Dr Tolmie claims that the workings of the natural world have always interested her, especially how it can be used to sustainably improve human health and agriculture. Observing some of the health challenges in Africa motivated her to take the opportunity to work with Prof Dirk Opperman, Associate Professor in the UFS Department of Microbiology and Biochemistry. Prof Opperman is a GCRF START co-investigator in the UFS Biocatalysis and Structural Biology research group, working on various bacterial and fungal enzymes.

Focusing on structural biology, Dr Tolmie is also working on drug discovery projects to find a sustainable solution through novel antifungal drugs.

To conduct the research that can improve the health of so many people suffering from infectious fungal diseases that can be serious, especially for immunocompromised patients living with HIV/Aids, recipients of organ transplants, patients undergoing chemotherapy and many more, Dr Tolmie will be using the drug discovery method of X-ray crystallographic fragment screening at Diamond Light Source (Diamond). “I was introduced to the concept and power of fragment screening techniques during GCRF START meetings,” says Dr Tolmie.

A research visit to Diamond Light Source in the UK in 2019, where she learned more about the experimental workflow of XChem and the i04-1 beamline, also inspired her to embark on XChem projects for antifungal drug discovery.

 

Exposed to cutting-edge scientific techniques

She attributes her recent appointment as lecturer to the mentoring and training she received through the GCRF START grant, which also funded a secondment to Diamond and the University of Oxford, exposing her to cutting-edge scientific techniques such as XChem fragment screening.

Prof Chris Nicklin, Science Group Leader and Principal Investigator in the GCRF START grant programme, says by providing the new generation of synchrotron users with access to world-class equipment and investing in their skills and capacity, research in the UK and Africa has been enriched and deepened.

“Being involved in the START grant has made a very concrete contribution to my career as a young scientist. GCRF START has also exposed me to many esteemed international scientists and facilities,” says Dr Tolmie.

Specifically alluding to the research that Dr Tolmie is working on, Dr Gwyndaf Evans, START Life Sciences Principal Investigator and principal beamline scientist on Diamond’s VMXm beamline, says: “It has been rewarding to see the relatively modest investment of time and money have such a major impact on the sustainability of research expertise, on the development of careers in Africa, on access to large-scale facilities around the world, and on the nurturing of collaborations and networks in South Africa.”

He continues: “In structural biology, there have been valuable exchanges and collaborations, especially XChem laying the foundations for drug discovery work. START is the beginning of embedding the structural research culture in South Africa and other groups around the world. We look forward to what the future holds.”

Dr Tolmie, who completed her BSc degree in Molecular Biology and Biotechnology at Stellenbosch University, completed her postgraduate studies (BSc Honours degree, MSc, and PhD) at the UFS.

News Archive

UFS History lecturer becomes Visiting Fellow at Harvard
2015-05-25

Dr Chitja Twala
Photo: Eugene Seegers

Prestige Scholar and lecturer of African/South African History at the UFS, Dr Chitja Twala, was recently accepted as a Visiting Fellow at the Harvard Graduate School of Arts and Sciences (GSAS).

A Visiting Fellow status is available to individuals holding a doctoral degree to pursue independent research at Harvard. The Fellowship is for non-degree purposes but aims at the enhancement and further intellectual development of those involved. It focuses on enrichment and development programmes.

Twala was appointed in the Department of History at the UFS in the beginning of 2003. His research field is Liberation History, with specific reference to the liberation movements on the SADC region. He has published extensively on this field and presented papers in local and international conferences.

“I applied (to Harvard GSAS) in April 2014 for the Fellowship through the South Africa Harvard Fellowship Programme,” says Twala.

“After being successful in the interviews conducted by the GSAS panel in July 2014, I had to apply for admission in the Department of African and African American Studies at Harvard, and got accepted for the Fall Semester of 2015.”

At Harvard, Twala will be mentored by Prof Emmanuel Akyeampong (African History Expert).

“Firstly, my main assignment will be to grasp a much deeper theoretical knowledge/framework in historical studies and a broader repertoire of methodologies in the field of African History. Secondly, if time permits, I will be presenting seminars and attending some in a very challenging, stimulating, and intellectually demanding environment where my ideas can be tested and expanded. Thirdly, I will be exposed to new trends as far as African historiography is concerned. Lastly, I will informally engage and exchange some ideas with some experts in the field of African History.”

The programme was recommended to Twala by the Vice-Chancellor and Rector, Prof Jonathan Jansen and Prof Ian Phimister, Centre for Africa Studies Senior Professor at UFS.

“As per the priorities of the Prestige Scholarship Programme, the Fellowship will assist in inculcating in me the intellectual breadth and depth required to pose critical questions and generate ground-breaking knowledge for History as a discipline. It is important for the UFS to establish and sustain international networks with other leading universities and scholars around the world.

“I applied for this Fellowship in order to advance further and broaden the scope in the three areas of scholarship in higher education: discovery, teaching, and public engagement,” says Twala.

Twala will be leaving for Harvard by mid-August and will return by the end of December 2015.

We use cookies to make interactions with our websites and services easy and meaningful. To better understand how they are used, read more about the UFS cookie policy. By continuing to use this site you are giving us your consent to do this.

Accept