Latest News Archive

Please select Category, Year, and then Month to display items
Previous Archive
08 June 2021 | Story Dr Nitha Ramnath

As a public higher-education institution in South Africa with a responsibility to contribute to public discourse, the University of the Free State (UFS) will be presenting the webinar as part of the Free State Literature Festival’s online initiative, VrySpraak-digitaal. The aim of the webinar series is to discuss issues facing South Africa by engaging experts at the university and in South Africa. Some of the topics for 2021 include, among others, reimagining universities for student success; corruption; local elections, the state of business – particularly in the Free State.

In 2020, the webinar series saw the successful participation of leading experts engaging on COVID-19 and the crisis facing the country socially, economically, and politically. This year, in lieu of the Free State Arts Festival, the UFS will present the webinar virtually over a period of five months.

Third webinar presented on 29 June 2021

South African local government has often been the target of protests due to poor service delivery. This either suggests that local government is not capable of carrying out technical tasks, or that constituents are not being heard by the representatives they elected.  Without capable and ethical politicians, the best institutions and policies in a country will serve no purpose if they are not protected. Institutions run the risk of being ineffective and not reaching their full potential in an environment without an ethical framework and the required human capabilities. South Africa suffers severe capability deficiencies due to poor political management that requires fixing at a political level.  

Will the forthcoming local government elections be the solution to much-needed change OR will electoral reform – a somewhat far-fetched ideal – provide the platform for ultimate change?

Date: Tuesday, 29 June 2021
Topic:  South African politics and the local government elections: scene setter for a capable state?
Time: 12:30-14:00
RSVP: Alicia Pienaar, pienaaran1@ufs.ac.za by 26 June 2021

Facilitator:

Prof Francis Petersen
Rector and Vice-Chancellor, UFS

Panellists:

Dr Ferial Haffajee
Associate Editor
Daily Maverick

• Prof Susan Booysen
Director of Research
Mapungubwe Institute for Strategic Reflection (MISTRA)

Mr Ebrahim Fakir
Director of Programmes
Auwal Socio-Economic Research Institute (ASRI)

Prof Sethulego Matebesi
Associate Professor and Academic Head of the Department of Sociology
University of the Free State

Bios of speakers:

Dr Ferial Haffajee

Ferial Haffajee is a South African editor and journalist. She is currently associate editor at the Daily Maverick. Previously, Ferial was editor-in-chief at the Mail & Guardian and City Press, where teams working with her won numerous investigative journalism awards.  She is a regular analyst and commentator on radio, television, and elsewhere. Ferial is a member of the Aspen Global Leadership Network and a member of the African Leadership Institute.   She serves on the board of the Open Society Programme on Independent Journalism. She has won numerous awards for journalism and for her support of media freedom, including an International Press Freedom Hero award from the Committee to Protect Journalists in 2015 and the Naspers Phil Weber award in 2013 – the global company’s highest internal honour.   Previously, Ferial was chairperson of the South African National Editors’ Forum and chairperson of the CNN/MultiChoice African Journalist of the Year Awards. She has served on the boards of the World Editors Forum and the Global Editors Network. She published a best-selling book called What if there were no whites in South Africa, and in 2017 she was awarded an honorary doctorate from the University of the Free State for her journalism.

Prof Susan Booysen

Prof Susan Booysen is a political scientist, author, and analyst of South African politics. She is also Director of Research at the Mapungubwe Institute for Strategic Reflection (MISTRA), emeritus professor at the University of the Witwatersrand, and visiting professor at the Wits School of Governance.

Booysen’s third book in her Wits University Press trilogy of research-driven books on the African National Congress of South Africa, Precarious Power: Compliance and discontent under Ramaphosa’s ANC, was published in March 2021. The first two parts of the set were The African National Congress and the Regeneration of Political Power (2011) and Dominance and Decline: The ANC in the Time of Zuma (2015). Precarious Power (http://witspress.co.za/catalogue/precarious-power/) is available from South African bookshops and digitally from online stores such as Amazon’s Kindle Store and Barnes & Noble.

Booysen also edited a range of books on South and Southern African politics. Her latest edited volume for the Mapungubwe Institute is Marriages of Inconvenience: Coalition politics in South Africa (July 2021). Her previous edited books are FeesMustFall: Student Revolt, Decolonisation and Governance in South Africa (WUP, 2016) and Local Elections in South Africa: People, parties, politics (SUN Press, 2012). She co-edited Democracy and Elections in Southern Africa (2009) with Denis Kadima.

Mr Ebrahim Fakir

Ebrahim Fakir is currently Director of Programmes at the Auwal Socio-Economic Research Institute (ASRI). He was awarded the 2014 Ruth First Fellowship at the University of the Witwatersrand and was a part-time lecturer in the WITS School of Governance in 2018.  Until October 2016, he was head of the Political Parties and Parliamentary Programme in the Electoral Institute (EISA) [2009-2016], where he edited and published the Election Update focusing on the analysis of SA elections. He was an editorial adviser to the independent start-up media house Daily Vox and regularly contributes analysis, opinion and comment articles to POLITY, the Mail & Guardian, Sunday Times, News 24, and Business Day, among others.

Formerly a senior researcher and analyst in the Centre for Policy Studies in Johannesburg (2003-2009), he worked in both the Pretoria and Cape Town offices of the Institute for Democracy in South Africa (IDASA – 1998-2003), and also in the Legislation and Oversight Division of the first democratic Parliament of the Republic of South Africa (1996-1998). Before that, he was a tutor in English Literature at the then University of Durban-Westville (1994-1996), writing for the popular press as well as for academic and policy journals on politics, development, and the state.

He read for a degree in English Literature at the University of the Witwatersrand, where he was elected to the Student Representative Council. He was a visiting fellow at the Institute of Development Studies at the University of Sussex (2006) and a Draper Hills Summer Fellow at the Centre on Democracy, Development and the Rule of Law at Stanford University in 2011.

Prof Sethulego Matebesi

Sethulego Matebesi is Associate Professor and Academic Head of the Department of Sociology at the University of the Free State. Matebesi’s primary research interest is social movements, community development, and mining-company-community relations. He is particularly interested in understanding the role of trust in community protests at municipal level and the conflict between mining companies and mining communities in South Africa. His recent publications include two monographs – Social licensing and mining in South Africa (2020), and Civil strife against local governance: Dynamics of community protests in South Africa (2017).

News Archive

Research contributes to improving quality of life for cancer patients
2016-11-21

Description: Inorganic Chemistry supervisors  Tags: Inorganic Chemistry supervisors

Inorganic Chemistry supervisors in the Radiopharmacy
Laboratory during the preparation of a typical complex
mixture to see how fast it reacts. Here are, from the left,
front: Dr Marietjie Schutte-Smith, Dr Alice Brink
(both scholars from the UFS Prestige
Scholar Programme), and Dr Truidie Venter (all three
are Thuthuka-funded researchers).
Back: Prof André Roodt and Dr Johan Venter.
Photo: Supplied

Imagine that you have been diagnosed with bone cancer and only have six months to live. You are in a wheelchair because the pain in your legs is so immense that you can’t walk anymore – similar to a mechanism eating your bones from the inside.

You are lucky though, since you could be injected with a drug to control the pain so effective that you will be able to get out of the wheelchair within a day-and-a-half and be able to walk again. Real-life incidents like these provide intense job satisfaction to Prof André Roodt, Head of Inorganic Chemistry at the University of the Free State (UFS). The research, which is conducted by the Inorganic Group at the UFS, contributes greatly to the availability of pain therapy that does not involve drugs, but improves the quality of life for cancer patients.

The research conducted by the Inorganic Group under the leadership of Prof Roodt, plays a major role in the clever design of model medicines to better detect and treat cancer.

The Department of Chemistry is one of approximately 10 institutions worldwide that conducts research on chemical mechanisms to identify and control cancer. “The fact that we are able to cooperate with the Departments of Nuclear Medicine and Medical Physics at the UFS, the Animal Research Centre, and other collaborators in South Africa and abroad, but especially the methodology we utilise to conduct research (studying the chemical manner in which drugs are absorbed in cancer as well as the time involved), enhances the possibility of making a contribution to cancer research,” says Prof Roodt.

Technique to detect cancer spots on bone
According to the professor, there are various ways of detecting cancer in the body. Cancer can, inter alia, be identified by analysing blood, X-rays (external) or through an internal technique where the patient is injected with a radioactive isotope.

Prof Roodt explains: “The doctor suspects that the patient has bone cancer and injects the person with a drug consisting of an isotope (only emits X-rays and does no damage to tissue) that is connected to a phosphonate (similar to those used for osteoporosis). Once the drug is injected, the isotope (Technetium-99m) moves to the spot on the bone where the cancer is located. The gamma rays in the isotope illuminate the area and the doctor can see exactly where treatment should be applied. The Technetium-99m has the same intensity gamma rays as normal X-rays and therefore operates the same as an internal X-ray supply.” With this technique, the doctor can see where the cancer spots are within a few hours.

The same technique can be used to identify inactive parts of the brain in Alzheimer patients, as well as areas of the heart where there is no blood supply or where the heart muscle is dead.

Therapeutic irradiation of cancer
For the treatment of pain connected with cancer, the isotope Rhenium-186 is injected. Similar to the manner in which the Technetium-99m phosphonate compound is ingested into the body, the Rhenium-186 phosphonate travels to the cancer spots. Patients thus receive therapeutic irradiation – a technique known as palliative therapy, which is excellent for treating pain. A dosage of this therapy usually lasts for about two months.

The therapy is, however, patient specific. The dosages should correspond with the occurrence and size of cancer spots in the patient’s body. First, the location of the cancer will be determined by means of a technetium scan. After that, the size of the area where the cancer occurs has to be determined. The dosage for addressing total pain distribution will be calculated according to these results.

Technique to detect cancer spots on soft tissue
Another technique to detect cancer as spots on bone or in soft tissue and organs throughout the body is by utilising a different type of irradiation, a so-called PET isotope. The Fluor-18 isotope is currently used widely, and in Pretoria a machine called a cyclotron was produced by Dr Gerdus Kemp, who is a former PhD graduate from the Inorganic Research Group. The F-18 is then hidden within a glucose molecule and a patient will be injected with the drug after being tranquillised and after the metabolism has been lowered considerably. The glucose, which is the ‘food' that cancer needs to grow, will then travel directly to the cancer area and the specific area where the cancer is located will thus be traced and ‘illuminated’ by the Fluor-18, which emits its own 'X-rays'.

In the late 80s, Prof Roodt did his own postdoctoral study on this research in the US. He started collaborating with the Department of Nuclear Medicine at the UFS in the early 90s, when he initiated testing for this research.

Through their research of more than 15 years, the Inorganic Group in the Department of Chemistry has made a major contribution to cancer research. Research on mechanisms for the detection of cancer, by designing new clever chemical agents, and the chemical ways in which these agents are taken up in the body, especially contributes to the development in terms of cancer therapy and imaging, and has been used by a number of hospitals in South Africa.

The future holds great promise
Prof Roodt and his team are already working on a bilateral study between the UFS and Kenya. It involves the linking of radio isotopes, as mentioned above, to known natural products (such as rooibos tea), which possess anti-cancer qualities.

We use cookies to make interactions with our websites and services easy and meaningful. To better understand how they are used, read more about the UFS cookie policy. By continuing to use this site you are giving us your consent to do this.

Accept