Latest News Archive

Please select Category, Year, and then Month to display items
Previous Archive
15 June 2021 | Story Leonie Bolleurs | Photo Supplied
Zurika Murray says the study of Behavioural Genetics at the UFS focuses on human behaviour, specifically neurotransmitter systems, such as serotonin that may contribute to specific behavioural patterns.
Zurika Murray says the study of Behavioural Genetics at the UFS focuses on human behaviour, specifically neurotransmitter systems, such as serotonin that may contribute to specific behavioural patterns.

Hi. I am John. I have anger issues.

Just like John, there are thousands of South Africans with anger issues, often leading to violent crimes such as the more than 21 000 murder cases and 165 000 plus assault cases reported in 2020, according to a study by the South African Police Service and Statistics South Africa.

Aggression can be a great threat to society when it leads to violence. However, it can also be an absolute necessity when it leads to perseverance and a drive towards success and survival. This is according to Zurika Murray, a lecturer in the Department of Genetics at the University of the Free State (UFS), who is doing research on behavioural genetics.

 

Behavioural genetics

She explains behavioural genetics as a study of genetic variation contributing to how an organism interacts with and within its environment. “At the UFS, we focus on human behaviour, and specifically neurotransmitter systems, such as serotonin that may contribute to specific behavioural patterns.”

When one has the right amount of serotonin in your body, it is easier to have stable moods and a sense of well-being.

She says the neurotransmitter (which plays a role in, among others, emotional regulation) acts as a mediator, relaying messages and influencing response to environmental stimuli.  “This system is very adaptable, facilitating our functioning in an ever-changing emotional environment; but when dysfunctional, it can cause quite a number of abnormalities, from anxiety and depression to dysfunctional impulse control and violence. When some individuals are exposed to adverse developmental environments such as abuse and neglect, they can develop aggression and violence.”

“One of our current projects looks specifically at male juvenile delinquency and monoamine neurotransmitter systems (such as serotonin) that may contribute to specific characteristics (such as impulsivity) of delinquency.”

According to Murray, their research is also looking at the genetic variation within specific neurotransmitter genes to see if they could find similarities among individuals with similar developmental backgrounds.  “This neurotransmitter system additionally responds relatively well to physical activity as a management strategy for aggression in some individuals. We are looking at variations in this system that might explain this,” says Murray.

 

Genetic counselling

Apart from the genetic contribution, we also know that the developmental environment plays a very important role. Many people observe anger while growing up – it was thus part of their developmental environment. For them, it is appropriate behaviour in specific situations.

To understand this contribution from the developmental environment, a background in psychology is necessary.  The undergraduate degree in Behavioural Genetics at the UFS has Genetics and Psychology as majors, and this is where the link to genetic counselling comes in.

Murray explains that genetic counselling is a field in medical sciences focusing on helping patients affected by medical conditions to understand the underlying genetics.  For individuals with a family history of genetic conditions (such as specific cancers) or pregnant mothers with foetuses affected by genetic abnormalities (such as Down syndrome), the services of a genetic counsellor are invaluable.  A genetic counsellor will help these individuals understand the cause of the disorder, how it was diagnosed, what the symptoms are, what the progression will look like, if any treatment is available, and what the possible options are (if any) for alternatives.

Genetic counsellors need a strong background in both Genetics and Psychology. To become a registered genetic counsellor, a student completes a BSc degree in Biological Sciences (Behavioural Genetics at the UFS would be ideal).  Thereafter an honours degree in either Genetics or Psychology (though Genetics is preferable).  The student can then apply at either the University of the Witwatersrand or the University of Cape Town for a master’s degree in Genetic Counselling.  This entails two years of study, followed by two years of practical internship. Only after this you will be able to register with the Health Professions Council of South Africa (HPCSA) as a genetic counsellor.

Students studying Behavioural Genetics at the UFS are off to a great start. Murray’s teaching philosophy is to always strive to deliver students who are better than she is. “I can only really do this by sharing my passion for my research. I hope to inspire my students to also always be hungrily curious, to always question, and to find the joy in knowledge and learning.”

News Archive

Young researchers are equipped to participate in projects relevant in global context
2017-09-05

 Description: Wheat genomics Tags: bioinformatics, Dr Renée Prins, Department of Plant Sciences, DNA and RNA, data sets 

This group of early career researchers received bioinformatics
training in Worcester in the UK from Dr Diane Saunders of the
John Innes Centre in the UK.
Photo: Supplied

The interdisciplinary field that develops methods and software tools to understand biological data is known as bioinformatics. According to Dr Renée Prins, a research fellow in the Department of Plant Sciences at the University of the Free State, there are few tertiary institutions in South Africa that offer a postgraduate degree in Bioinformatics.

“Most institutions focus either on humans, human diseases, forest trees and their pathogens.  They usually do not have spare capacity to assist researchers, for instance, those working on crops in the agricultural sector,” Dr Prins said.

Big data sets need significant skills

With the advancements made in genomics such as high throughput DNA marker platforms and next-generation sequencing technologies, the data sets biologists have to deal with have grown massively big and cannot be dealt with unless you have significant computer skills.

Dr Prins believes that all young researchers need some level of training in this field to be effective in future. The British Council Researcher Links, being run by the Newton Fund, gives early career researchers across selected partner countries the opportunity to form international connections through fully funded workshops and travel grants. Dr Prins made use of this opportunity and with the assistance of the Department of Research Development at the UFS, she arranged for Dr Diane Saunders of the John Innes Centre in the UK, a bioinformatician of note, to present training to a group of 20 early career researchers in Worcester in the UK.

Providing training with Dr Saunders were two other bioinformaticians from the UK, Dr Burkhard Steuernagel (John Innes Centre) and Dr Robert Davey (Earlham Institute). From the UFS side, Eleanor van der Westhuizen and Dr Henriëtte van den Berg (former UFS academic) acted as mentors, providing guidance on funding opportunities and career development skills.

Participating in projects in a global context
The researchers attending the training came from research institutions or academia, and they work involving plants (predominantly wheat) or plant pathogens. A limited number of participants from the commercial sector, including private South African companies focusing on plant breeding and molecular genetics lab work on agriculturally important crops also benefited from the training. 

“Tertiary institutions in South Africa have the obligation to ensure that young scientists are equipped with bioinformatics skills. If they are not equipped with the necessary skills, they will not be able to participate in research projects that are relevant in a global context,” said Dr Prins. 

We use cookies to make interactions with our websites and services easy and meaningful. To better understand how they are used, read more about the UFS cookie policy. By continuing to use this site you are giving us your consent to do this.

Accept