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15 June 2021 | Story Leonie Bolleurs | Photo Supplied
Zurika Murray says the study of Behavioural Genetics at the UFS focuses on human behaviour, specifically neurotransmitter systems, such as serotonin that may contribute to specific behavioural patterns.
Zurika Murray says the study of Behavioural Genetics at the UFS focuses on human behaviour, specifically neurotransmitter systems, such as serotonin that may contribute to specific behavioural patterns.

Hi. I am John. I have anger issues.

Just like John, there are thousands of South Africans with anger issues, often leading to violent crimes such as the more than 21 000 murder cases and 165 000 plus assault cases reported in 2020, according to a study by the South African Police Service and Statistics South Africa.

Aggression can be a great threat to society when it leads to violence. However, it can also be an absolute necessity when it leads to perseverance and a drive towards success and survival. This is according to Zurika Murray, a lecturer in the Department of Genetics at the University of the Free State (UFS), who is doing research on behavioural genetics.

 

Behavioural genetics

She explains behavioural genetics as a study of genetic variation contributing to how an organism interacts with and within its environment. “At the UFS, we focus on human behaviour, and specifically neurotransmitter systems, such as serotonin that may contribute to specific behavioural patterns.”

When one has the right amount of serotonin in your body, it is easier to have stable moods and a sense of well-being.

She says the neurotransmitter (which plays a role in, among others, emotional regulation) acts as a mediator, relaying messages and influencing response to environmental stimuli.  “This system is very adaptable, facilitating our functioning in an ever-changing emotional environment; but when dysfunctional, it can cause quite a number of abnormalities, from anxiety and depression to dysfunctional impulse control and violence. When some individuals are exposed to adverse developmental environments such as abuse and neglect, they can develop aggression and violence.”

“One of our current projects looks specifically at male juvenile delinquency and monoamine neurotransmitter systems (such as serotonin) that may contribute to specific characteristics (such as impulsivity) of delinquency.”

According to Murray, their research is also looking at the genetic variation within specific neurotransmitter genes to see if they could find similarities among individuals with similar developmental backgrounds.  “This neurotransmitter system additionally responds relatively well to physical activity as a management strategy for aggression in some individuals. We are looking at variations in this system that might explain this,” says Murray.

 

Genetic counselling

Apart from the genetic contribution, we also know that the developmental environment plays a very important role. Many people observe anger while growing up – it was thus part of their developmental environment. For them, it is appropriate behaviour in specific situations.

To understand this contribution from the developmental environment, a background in psychology is necessary.  The undergraduate degree in Behavioural Genetics at the UFS has Genetics and Psychology as majors, and this is where the link to genetic counselling comes in.

Murray explains that genetic counselling is a field in medical sciences focusing on helping patients affected by medical conditions to understand the underlying genetics.  For individuals with a family history of genetic conditions (such as specific cancers) or pregnant mothers with foetuses affected by genetic abnormalities (such as Down syndrome), the services of a genetic counsellor are invaluable.  A genetic counsellor will help these individuals understand the cause of the disorder, how it was diagnosed, what the symptoms are, what the progression will look like, if any treatment is available, and what the possible options are (if any) for alternatives.

Genetic counsellors need a strong background in both Genetics and Psychology. To become a registered genetic counsellor, a student completes a BSc degree in Biological Sciences (Behavioural Genetics at the UFS would be ideal).  Thereafter an honours degree in either Genetics or Psychology (though Genetics is preferable).  The student can then apply at either the University of the Witwatersrand or the University of Cape Town for a master’s degree in Genetic Counselling.  This entails two years of study, followed by two years of practical internship. Only after this you will be able to register with the Health Professions Council of South Africa (HPCSA) as a genetic counsellor.

Students studying Behavioural Genetics at the UFS are off to a great start. Murray’s teaching philosophy is to always strive to deliver students who are better than she is. “I can only really do this by sharing my passion for my research. I hope to inspire my students to also always be hungrily curious, to always question, and to find the joy in knowledge and learning.”

News Archive

Early diagnosis of hearing loss is important
2017-09-11

  Description: Magteld small Tags: birth defects, hearing loss, Dr Magteld Smith, Department of Otorhinolaryngology

Dr Magteld Smith, lecturer in the
Department of Otorhinolaryngology
at the University of the Free State (UFS)
Photo: Supplied


One of the most common, misunderstood and neglected birth defects in developing countries is hearing loss, which can most severely impair and have a dramatic impact of the quality of life the of the person with hearing loss. 

This is according to Dr Magteld Smith, lecturer in the Department of Otorhinolaryngology at the University of the Free State (UFS). 

“Hearing loss refers to all the different types and levels of hearing loss, from slight to profound hearing loss,” she said. 

Derived from a number of retrospective studies in South Africa, it was found 17 people a day are born with hearing loss. More than 95% of those children are born to hearing parents. This estimate excludes children and adults who lost their hearing after birth. 

According to Dr Smith, hearing loss strikes at the very essence of being human, because it hinders communication with others. To enable people to communicate with those with hearing loss, the university’s Department of South African Sign Language teaches students sign language. This year, the department enrolled 230 students. A number of these students are from the Faculty of Education. These students could from 2017 for the first time choose sign language as a subject.

“Studies have shown that important language skills are learned before the age of three because hearing and learning language are closely tied together. Brain development of the auditory pathways and language cortex is occurring in young children as they respond to auditory and visual language. In families that are part of deaf culture, these parents automatically sign from day one, so the baby is learning visual (sign) language, and the appropriate brain development is occurring.

Beskrywing: Doof readmore Sleutelwoorde: geboorte-afwykings, gehoorverlies, dr Magteld Smith, Departement Otorinolaringologie

About 230 students are enrolled for the subject, South African 
Sign Language, at the UFS. As an assignment some of the students 
were asked to design posters to create deaf awareness among 
others on campus. From the left are: Poleliso Mpahane, 
Masajin Koalepe, Ntshitsa Mosase, and Zoleka Ncamane. 
Photo: Leonie Bolleurs

“However, if a child has an undiagnosed hearing loss and the parents are unaware, the child will not receive the needed language stimulation — and the hoped-for development won’t take place. It is critical to understand that children with hearing loss have their own talents, different levels of intelligence, socioeconomic circumstances and different abilities, just like hearing children. Therefore, one size does not fit all,” Dr Smith said. 

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