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15 June 2021 | Story Leonie Bolleurs | Photo Supplied
Zurika Murray says the study of Behavioural Genetics at the UFS focuses on human behaviour, specifically neurotransmitter systems, such as serotonin that may contribute to specific behavioural patterns.
Zurika Murray says the study of Behavioural Genetics at the UFS focuses on human behaviour, specifically neurotransmitter systems, such as serotonin that may contribute to specific behavioural patterns.

Hi. I am John. I have anger issues.

Just like John, there are thousands of South Africans with anger issues, often leading to violent crimes such as the more than 21 000 murder cases and 165 000 plus assault cases reported in 2020, according to a study by the South African Police Service and Statistics South Africa.

Aggression can be a great threat to society when it leads to violence. However, it can also be an absolute necessity when it leads to perseverance and a drive towards success and survival. This is according to Zurika Murray, a lecturer in the Department of Genetics at the University of the Free State (UFS), who is doing research on behavioural genetics.

 

Behavioural genetics

She explains behavioural genetics as a study of genetic variation contributing to how an organism interacts with and within its environment. “At the UFS, we focus on human behaviour, and specifically neurotransmitter systems, such as serotonin that may contribute to specific behavioural patterns.”

When one has the right amount of serotonin in your body, it is easier to have stable moods and a sense of well-being.

She says the neurotransmitter (which plays a role in, among others, emotional regulation) acts as a mediator, relaying messages and influencing response to environmental stimuli.  “This system is very adaptable, facilitating our functioning in an ever-changing emotional environment; but when dysfunctional, it can cause quite a number of abnormalities, from anxiety and depression to dysfunctional impulse control and violence. When some individuals are exposed to adverse developmental environments such as abuse and neglect, they can develop aggression and violence.”

“One of our current projects looks specifically at male juvenile delinquency and monoamine neurotransmitter systems (such as serotonin) that may contribute to specific characteristics (such as impulsivity) of delinquency.”

According to Murray, their research is also looking at the genetic variation within specific neurotransmitter genes to see if they could find similarities among individuals with similar developmental backgrounds.  “This neurotransmitter system additionally responds relatively well to physical activity as a management strategy for aggression in some individuals. We are looking at variations in this system that might explain this,” says Murray.

 

Genetic counselling

Apart from the genetic contribution, we also know that the developmental environment plays a very important role. Many people observe anger while growing up – it was thus part of their developmental environment. For them, it is appropriate behaviour in specific situations.

To understand this contribution from the developmental environment, a background in psychology is necessary.  The undergraduate degree in Behavioural Genetics at the UFS has Genetics and Psychology as majors, and this is where the link to genetic counselling comes in.

Murray explains that genetic counselling is a field in medical sciences focusing on helping patients affected by medical conditions to understand the underlying genetics.  For individuals with a family history of genetic conditions (such as specific cancers) or pregnant mothers with foetuses affected by genetic abnormalities (such as Down syndrome), the services of a genetic counsellor are invaluable.  A genetic counsellor will help these individuals understand the cause of the disorder, how it was diagnosed, what the symptoms are, what the progression will look like, if any treatment is available, and what the possible options are (if any) for alternatives.

Genetic counsellors need a strong background in both Genetics and Psychology. To become a registered genetic counsellor, a student completes a BSc degree in Biological Sciences (Behavioural Genetics at the UFS would be ideal).  Thereafter an honours degree in either Genetics or Psychology (though Genetics is preferable).  The student can then apply at either the University of the Witwatersrand or the University of Cape Town for a master’s degree in Genetic Counselling.  This entails two years of study, followed by two years of practical internship. Only after this you will be able to register with the Health Professions Council of South Africa (HPCSA) as a genetic counsellor.

Students studying Behavioural Genetics at the UFS are off to a great start. Murray’s teaching philosophy is to always strive to deliver students who are better than she is. “I can only really do this by sharing my passion for my research. I hope to inspire my students to also always be hungrily curious, to always question, and to find the joy in knowledge and learning.”

News Archive

New schools, restructuring part of streamlined Faculty of Health Sciences
2017-10-12

 Description: Health Sciences staff 2 Tags: Faculty of Health Sciences, five-school structure, Prof Gert van Zyl, Pathology, Biomedical Sciences  

From the left, front are: Dr Jocelyn Naicker,
Prof Gert van Zyl, Prof Magda Mulder;
back from left: Prof Chris Viljoen,
Marlene Viljoen, Deputy Director: Faculty of Health Sciences;
Prof Nathaniel Mofolo; and Prof Santie van Vuuren.
Photo: Rulanzen Martin


Numerous developments, such as the creation of two new schools and one newly restructured School of Medicine in the Faculty of Health Sciences at the University of the Free State (UFS), will catapult this renowned faculty to even greater heights.

Five-school structure to increase access
 
A five-school structure was proposed at the annual Faculty Management retreat in July 2016. The previous three-school model included the Schools of Medicine, Nursing, and Allied Health Professions.

The current School of Medicine has been restructured and will henceforth be known as the School of Clinical Medicine. The Schools of Pathology and Biomedical Sciences have been added to the faculty. “So, three new schools were in fact created within the faculty,” said Prof Gert van Zyl, Dean of the faculty.   

“There was also a request from the National Health Laboratory Services to group academics that is rendering services in pathology into a new School of Pathology.” This is what motivated the faculty management to create two new schools.

Esteemed academics appointed 

With the creation of the new schools, there were also new appointments within the Faculty of Health Sciences. Dr Jocelyn Naicker has been appointed as the new part-time Head of the School of Pathology, Prof Chris Viljoen was appointed as the part-time Head of the School of Biomedical Sciences, and Prof Nathaniel Mofolo as the new Head of the School of Clinical Medicine. Prof Santie van Vuuren remains Head of the School of Allied Health Professions, and Prof Magda Mulder as the head of the School of Nursing. 

Research outputs to remain as usual
The addition of the new schools will not impact research output. “In the past, research was done across departmental boundaries between all the departments in the faculty,” Prof Van Zyl said. The advantages of adding two additional schools are that the workload will be distributed among the five schools. The heads of schools will work within their respective disciplines and related areas, and will eliminate the duplication of administrative functions.

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