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15 June 2021 | Story Leonie Bolleurs | Photo Supplied
Zurika Murray says the study of Behavioural Genetics at the UFS focuses on human behaviour, specifically neurotransmitter systems, such as serotonin that may contribute to specific behavioural patterns.
Zurika Murray says the study of Behavioural Genetics at the UFS focuses on human behaviour, specifically neurotransmitter systems, such as serotonin that may contribute to specific behavioural patterns.

Hi. I am John. I have anger issues.

Just like John, there are thousands of South Africans with anger issues, often leading to violent crimes such as the more than 21 000 murder cases and 165 000 plus assault cases reported in 2020, according to a study by the South African Police Service and Statistics South Africa.

Aggression can be a great threat to society when it leads to violence. However, it can also be an absolute necessity when it leads to perseverance and a drive towards success and survival. This is according to Zurika Murray, a lecturer in the Department of Genetics at the University of the Free State (UFS), who is doing research on behavioural genetics.

 

Behavioural genetics

She explains behavioural genetics as a study of genetic variation contributing to how an organism interacts with and within its environment. “At the UFS, we focus on human behaviour, and specifically neurotransmitter systems, such as serotonin that may contribute to specific behavioural patterns.”

When one has the right amount of serotonin in your body, it is easier to have stable moods and a sense of well-being.

She says the neurotransmitter (which plays a role in, among others, emotional regulation) acts as a mediator, relaying messages and influencing response to environmental stimuli.  “This system is very adaptable, facilitating our functioning in an ever-changing emotional environment; but when dysfunctional, it can cause quite a number of abnormalities, from anxiety and depression to dysfunctional impulse control and violence. When some individuals are exposed to adverse developmental environments such as abuse and neglect, they can develop aggression and violence.”

“One of our current projects looks specifically at male juvenile delinquency and monoamine neurotransmitter systems (such as serotonin) that may contribute to specific characteristics (such as impulsivity) of delinquency.”

According to Murray, their research is also looking at the genetic variation within specific neurotransmitter genes to see if they could find similarities among individuals with similar developmental backgrounds.  “This neurotransmitter system additionally responds relatively well to physical activity as a management strategy for aggression in some individuals. We are looking at variations in this system that might explain this,” says Murray.

 

Genetic counselling

Apart from the genetic contribution, we also know that the developmental environment plays a very important role. Many people observe anger while growing up – it was thus part of their developmental environment. For them, it is appropriate behaviour in specific situations.

To understand this contribution from the developmental environment, a background in psychology is necessary.  The undergraduate degree in Behavioural Genetics at the UFS has Genetics and Psychology as majors, and this is where the link to genetic counselling comes in.

Murray explains that genetic counselling is a field in medical sciences focusing on helping patients affected by medical conditions to understand the underlying genetics.  For individuals with a family history of genetic conditions (such as specific cancers) or pregnant mothers with foetuses affected by genetic abnormalities (such as Down syndrome), the services of a genetic counsellor are invaluable.  A genetic counsellor will help these individuals understand the cause of the disorder, how it was diagnosed, what the symptoms are, what the progression will look like, if any treatment is available, and what the possible options are (if any) for alternatives.

Genetic counsellors need a strong background in both Genetics and Psychology. To become a registered genetic counsellor, a student completes a BSc degree in Biological Sciences (Behavioural Genetics at the UFS would be ideal).  Thereafter an honours degree in either Genetics or Psychology (though Genetics is preferable).  The student can then apply at either the University of the Witwatersrand or the University of Cape Town for a master’s degree in Genetic Counselling.  This entails two years of study, followed by two years of practical internship. Only after this you will be able to register with the Health Professions Council of South Africa (HPCSA) as a genetic counsellor.

Students studying Behavioural Genetics at the UFS are off to a great start. Murray’s teaching philosophy is to always strive to deliver students who are better than she is. “I can only really do this by sharing my passion for my research. I hope to inspire my students to also always be hungrily curious, to always question, and to find the joy in knowledge and learning.”

News Archive

Using sugar to make the world a sweeter place
2017-10-13

Description: Deepback sugar Tags: Sugarcane, Dr Deepack Santchurn, Mauritius Sugar Industry Research Institute (MSIRI), Department of Plant Sciences 

Dr Deepack Santchurn, former PhD student in the
Department of Plant Sciences at the UFS,
and plant breeder in the  Mauritius Sugar Industry
Research Institute, with Prof Maryke Labuschagne, left,
Dr Santchurn’s study leader.
Photo: Charl Devenish



Besides it mainly being used for sugar production, sugarcane has emerged as an important alternative for providing clean renewable energy. Dr Deepack Santchurn, who works in the sugarcane breeding department of the Mauritius Sugar Industry Research Institute (MSIRI), believes if he could contribute towards a more environment-friendly and renewable energy through the use of sugarcane biomass, he would consider himself having made a great leap towards a better world. 

Sugarcane is mostly known and exploited for the sugar in its cane stem. According to Dr Santchurn it is not the only thing the crop does well. “Together with certain grasses, it is the finest living collector of sunlight energy and a producer of biomass in unit time. Sugarcane is now recognised worldwide as a potential renewable and environment-friendly bioenergy crop.” 

Significantly more bioenergy can be produced from sugarcane if the production system is not focused on the production and recovery of sucrose alone but on the maximum use to the total above-ground biomass. Diversification within the sugarcane industry is of paramount importance. 

He has been able to identify a few high biomass varieties that can be exploited industrially. One of the varieties is a commercial type with relatively high sugar and low fibre in the cane stem. Dr Santchurn explains: “Its sucrose content is about 0.5% less than the most cultivated commercial variety in Mauritius. Nevertheless, its sugar yield and above-ground biomass yield surpass those of the commercial varieties by more than 24%. The genetic gains compared to commercial varieties were around +50% for total biomass yield and +100% for fibre yield. Its cultivation is strictly related to bio-energy production and the extracted juice can be used as a feed-stock for ethanol and other high-value products.”

Dr Santchurn received his PhD at the UFS’s Department of Plant Sciences during the Winter Graduation Ceremonies in June this year. His study leader was Prof Maryke Labuschagne from the Department of Plant Sciences. 

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