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15 June 2021 | Story Leonie Bolleurs | Photo Supplied
Zurika Murray says the study of Behavioural Genetics at the UFS focuses on human behaviour, specifically neurotransmitter systems, such as serotonin that may contribute to specific behavioural patterns.
Zurika Murray says the study of Behavioural Genetics at the UFS focuses on human behaviour, specifically neurotransmitter systems, such as serotonin that may contribute to specific behavioural patterns.

Hi. I am John. I have anger issues.

Just like John, there are thousands of South Africans with anger issues, often leading to violent crimes such as the more than 21 000 murder cases and 165 000 plus assault cases reported in 2020, according to a study by the South African Police Service and Statistics South Africa.

Aggression can be a great threat to society when it leads to violence. However, it can also be an absolute necessity when it leads to perseverance and a drive towards success and survival. This is according to Zurika Murray, a lecturer in the Department of Genetics at the University of the Free State (UFS), who is doing research on behavioural genetics.

 

Behavioural genetics

She explains behavioural genetics as a study of genetic variation contributing to how an organism interacts with and within its environment. “At the UFS, we focus on human behaviour, and specifically neurotransmitter systems, such as serotonin that may contribute to specific behavioural patterns.”

When one has the right amount of serotonin in your body, it is easier to have stable moods and a sense of well-being.

She says the neurotransmitter (which plays a role in, among others, emotional regulation) acts as a mediator, relaying messages and influencing response to environmental stimuli.  “This system is very adaptable, facilitating our functioning in an ever-changing emotional environment; but when dysfunctional, it can cause quite a number of abnormalities, from anxiety and depression to dysfunctional impulse control and violence. When some individuals are exposed to adverse developmental environments such as abuse and neglect, they can develop aggression and violence.”

“One of our current projects looks specifically at male juvenile delinquency and monoamine neurotransmitter systems (such as serotonin) that may contribute to specific characteristics (such as impulsivity) of delinquency.”

According to Murray, their research is also looking at the genetic variation within specific neurotransmitter genes to see if they could find similarities among individuals with similar developmental backgrounds.  “This neurotransmitter system additionally responds relatively well to physical activity as a management strategy for aggression in some individuals. We are looking at variations in this system that might explain this,” says Murray.

 

Genetic counselling

Apart from the genetic contribution, we also know that the developmental environment plays a very important role. Many people observe anger while growing up – it was thus part of their developmental environment. For them, it is appropriate behaviour in specific situations.

To understand this contribution from the developmental environment, a background in psychology is necessary.  The undergraduate degree in Behavioural Genetics at the UFS has Genetics and Psychology as majors, and this is where the link to genetic counselling comes in.

Murray explains that genetic counselling is a field in medical sciences focusing on helping patients affected by medical conditions to understand the underlying genetics.  For individuals with a family history of genetic conditions (such as specific cancers) or pregnant mothers with foetuses affected by genetic abnormalities (such as Down syndrome), the services of a genetic counsellor are invaluable.  A genetic counsellor will help these individuals understand the cause of the disorder, how it was diagnosed, what the symptoms are, what the progression will look like, if any treatment is available, and what the possible options are (if any) for alternatives.

Genetic counsellors need a strong background in both Genetics and Psychology. To become a registered genetic counsellor, a student completes a BSc degree in Biological Sciences (Behavioural Genetics at the UFS would be ideal).  Thereafter an honours degree in either Genetics or Psychology (though Genetics is preferable).  The student can then apply at either the University of the Witwatersrand or the University of Cape Town for a master’s degree in Genetic Counselling.  This entails two years of study, followed by two years of practical internship. Only after this you will be able to register with the Health Professions Council of South Africa (HPCSA) as a genetic counsellor.

Students studying Behavioural Genetics at the UFS are off to a great start. Murray’s teaching philosophy is to always strive to deliver students who are better than she is. “I can only really do this by sharing my passion for my research. I hope to inspire my students to also always be hungrily curious, to always question, and to find the joy in knowledge and learning.”

News Archive

From lock to SA prop in six months
2017-10-26

 Description: Kwenzo Bloze Tags: Kwenzo Blose, KovsieSport’s, Junior Sportsman of 2016, World Championship, Shimla 

One of the rugby players that Kwenzo Blose looks
up to, is the Cheetah prop Ox Nche. He and Nche
are both residents of the Vishuis men’s residence.
Photo: Jóhann Thormählen


If someone told Kwenzo Blose of Glenwood High School that he would scrum as prop for the South African U/20 rugby team at the Junior World Championship, he would probably have thought it was a joke. At that time he still played lock, but only six months after the shift to prop, he represented his country at the tournament in Manchester, England.

Apart from this, KovsieSport’s Junior Sportsman of 2016 – who will probably be playing in his second World Championship this year, only became a Shimla in 2017. Last year he was still playing for the University of the Free State’s Young Guns.

Beast also played lock at first
André Tredoux, former UFS and Cheetah talent scout, said the Springbok prop Beast Mtawarira also played lock and flank at school. “Glenwood competed in the Wildeklawer Super Schools Tournament. Apparently coach André spotted me there and talked to Stephan Jacobs, another UFS coach. At that stage, I still played lock and they told each other that they had to get me to the Free State and convince me to play prop. I knew nothing of these plans,” said Blose.

According to this Paulpietersburg-native, who is 1,87 m tall and weighs 112 kg, he still has a lot to learn at prop. His greatest adjustments were in the scrums. “At prop you have to absorb the pressure of the rest of the pack in order to provide your team with front-foot ball,” he said. He said Jacobs, who was his Young Guns scrum coach, and Daan Human, the Cheetah scrum doctor, has helped him a lot.

An avid student off the field
Even though rugby has opened doors for the loose head who is studying LLB Law, he maintains a good balance. “The main reason why I came to university is to study. To be playing rugby and performing well is a great blessing, but I also have to prioritise and make sure that I obtain my degree.”

This year’s Junior World Championship was from 31 May to 18 June in Tbilisi, Georgia. Last year, the Baby Boks finished in a disappointing fourth place, but Blose believes they can improve on this. “If everything goes according to plan and if some of the guys are playing again, we would have something like nine players who played in the 2016 tournament.”

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