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15 June 2021 | Story Leonie Bolleurs | Photo Supplied
Zurika Murray says the study of Behavioural Genetics at the UFS focuses on human behaviour, specifically neurotransmitter systems, such as serotonin that may contribute to specific behavioural patterns.
Zurika Murray says the study of Behavioural Genetics at the UFS focuses on human behaviour, specifically neurotransmitter systems, such as serotonin that may contribute to specific behavioural patterns.

Hi. I am John. I have anger issues.

Just like John, there are thousands of South Africans with anger issues, often leading to violent crimes such as the more than 21 000 murder cases and 165 000 plus assault cases reported in 2020, according to a study by the South African Police Service and Statistics South Africa.

Aggression can be a great threat to society when it leads to violence. However, it can also be an absolute necessity when it leads to perseverance and a drive towards success and survival. This is according to Zurika Murray, a lecturer in the Department of Genetics at the University of the Free State (UFS), who is doing research on behavioural genetics.

 

Behavioural genetics

She explains behavioural genetics as a study of genetic variation contributing to how an organism interacts with and within its environment. “At the UFS, we focus on human behaviour, and specifically neurotransmitter systems, such as serotonin that may contribute to specific behavioural patterns.”

When one has the right amount of serotonin in your body, it is easier to have stable moods and a sense of well-being.

She says the neurotransmitter (which plays a role in, among others, emotional regulation) acts as a mediator, relaying messages and influencing response to environmental stimuli.  “This system is very adaptable, facilitating our functioning in an ever-changing emotional environment; but when dysfunctional, it can cause quite a number of abnormalities, from anxiety and depression to dysfunctional impulse control and violence. When some individuals are exposed to adverse developmental environments such as abuse and neglect, they can develop aggression and violence.”

“One of our current projects looks specifically at male juvenile delinquency and monoamine neurotransmitter systems (such as serotonin) that may contribute to specific characteristics (such as impulsivity) of delinquency.”

According to Murray, their research is also looking at the genetic variation within specific neurotransmitter genes to see if they could find similarities among individuals with similar developmental backgrounds.  “This neurotransmitter system additionally responds relatively well to physical activity as a management strategy for aggression in some individuals. We are looking at variations in this system that might explain this,” says Murray.

 

Genetic counselling

Apart from the genetic contribution, we also know that the developmental environment plays a very important role. Many people observe anger while growing up – it was thus part of their developmental environment. For them, it is appropriate behaviour in specific situations.

To understand this contribution from the developmental environment, a background in psychology is necessary.  The undergraduate degree in Behavioural Genetics at the UFS has Genetics and Psychology as majors, and this is where the link to genetic counselling comes in.

Murray explains that genetic counselling is a field in medical sciences focusing on helping patients affected by medical conditions to understand the underlying genetics.  For individuals with a family history of genetic conditions (such as specific cancers) or pregnant mothers with foetuses affected by genetic abnormalities (such as Down syndrome), the services of a genetic counsellor are invaluable.  A genetic counsellor will help these individuals understand the cause of the disorder, how it was diagnosed, what the symptoms are, what the progression will look like, if any treatment is available, and what the possible options are (if any) for alternatives.

Genetic counsellors need a strong background in both Genetics and Psychology. To become a registered genetic counsellor, a student completes a BSc degree in Biological Sciences (Behavioural Genetics at the UFS would be ideal).  Thereafter an honours degree in either Genetics or Psychology (though Genetics is preferable).  The student can then apply at either the University of the Witwatersrand or the University of Cape Town for a master’s degree in Genetic Counselling.  This entails two years of study, followed by two years of practical internship. Only after this you will be able to register with the Health Professions Council of South Africa (HPCSA) as a genetic counsellor.

Students studying Behavioural Genetics at the UFS are off to a great start. Murray’s teaching philosophy is to always strive to deliver students who are better than she is. “I can only really do this by sharing my passion for my research. I hope to inspire my students to also always be hungrily curious, to always question, and to find the joy in knowledge and learning.”

News Archive

Sarah, our own champion
2008-11-05

 
Sarah Shannon at the Paralympic Games in Beijing

 

Sarah Shannon, a second-year student in the Postgraduate Certificate in Education, has been involved in disability sport on national level for the past 12 years. Sarah has cerebral palsy.

In 1996 she participated at the South African National Championships for the physically disabled for the first time, entering for several sporting codes and winning five gold medals. In swimming she participates in the S3 class together with other swimmers that have comparable abilities to hers.

In 1997 she decided to focus on swimming competitively. She participated in her first national championships for swimming that year. After that (1998) she represented South Africa on international level at the International Paralympic Committee’s (IPC) Swimming World Championships in New Zealand where she ended 4th in the 50m backstroke and 7th in both the 50m and 100m freestyle in her class.

In 1999 she represented South Africa in Johannesburg at the 7th All Africa Games and won a silver medal for the 50m freestyle and a bronze medal for the 100m freestyle.

In 2000 she was part of the South African team at the Sydney Paralympic Games where she reached the finals and finished 7th in the 50m backstroke and 8th in the 50m freestyle. Northern-KwaZulu-Natal also awarded her the Junior Sportswoman of the Year award in 2001. In 2002 she participated at the South African Senior National swimming championships for KwaZulu-Natal in the multi-disability category.

In 2005 she completed the Midmar Mile. She also represented South Africa at the world championships for athletes with cerebral palsy in Boston in the United States of America. She won two gold medals for respectively the 50m freestyle and the 50m backstroke and two silver medals in the 100m and 200m freestyle. She was also nominated to represent South Africa as athlete’s representative on the world committee of CPISRA (Cerebral Palsy International Sports and Recreation Association). In this year Sarah also received the KwaZulu-Natal Premier’s Sportswoman with a disability award of the year.

In 2006 she qualified for the IPC world championships but could not attend.

In 2007 she represented South Africa once more at the Visa Paralympic World Cup in Manchester in the United Kingdom where she broke the South African record in the 50m backstroke, finishing 7th in the 50m freestyle and 6th in the 50m backstroke.

She was also part of the very successful Team South Africa to the Paralympic Games in Beijing. She reached the finals in both the 50m backstroke and 50m freestyle. She finished 7th in the 50m freestyle and 6th in the 50m backstroke in personal best times for both events. She has been participating in the able bodied South African National Swimming Championships since 2002. She is currently ranked 2nd in the world for short course items and 11th for the long course items. She is truly our best swimmer in the S3 class.
 

 

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