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15 June 2021 | Story Leonie Bolleurs | Photo Supplied
Zurika Murray says the study of Behavioural Genetics at the UFS focuses on human behaviour, specifically neurotransmitter systems, such as serotonin that may contribute to specific behavioural patterns.
Zurika Murray says the study of Behavioural Genetics at the UFS focuses on human behaviour, specifically neurotransmitter systems, such as serotonin that may contribute to specific behavioural patterns.

Hi. I am John. I have anger issues.

Just like John, there are thousands of South Africans with anger issues, often leading to violent crimes such as the more than 21 000 murder cases and 165 000 plus assault cases reported in 2020, according to a study by the South African Police Service and Statistics South Africa.

Aggression can be a great threat to society when it leads to violence. However, it can also be an absolute necessity when it leads to perseverance and a drive towards success and survival. This is according to Zurika Murray, a lecturer in the Department of Genetics at the University of the Free State (UFS), who is doing research on behavioural genetics.

 

Behavioural genetics

She explains behavioural genetics as a study of genetic variation contributing to how an organism interacts with and within its environment. “At the UFS, we focus on human behaviour, and specifically neurotransmitter systems, such as serotonin that may contribute to specific behavioural patterns.”

When one has the right amount of serotonin in your body, it is easier to have stable moods and a sense of well-being.

She says the neurotransmitter (which plays a role in, among others, emotional regulation) acts as a mediator, relaying messages and influencing response to environmental stimuli.  “This system is very adaptable, facilitating our functioning in an ever-changing emotional environment; but when dysfunctional, it can cause quite a number of abnormalities, from anxiety and depression to dysfunctional impulse control and violence. When some individuals are exposed to adverse developmental environments such as abuse and neglect, they can develop aggression and violence.”

“One of our current projects looks specifically at male juvenile delinquency and monoamine neurotransmitter systems (such as serotonin) that may contribute to specific characteristics (such as impulsivity) of delinquency.”

According to Murray, their research is also looking at the genetic variation within specific neurotransmitter genes to see if they could find similarities among individuals with similar developmental backgrounds.  “This neurotransmitter system additionally responds relatively well to physical activity as a management strategy for aggression in some individuals. We are looking at variations in this system that might explain this,” says Murray.

 

Genetic counselling

Apart from the genetic contribution, we also know that the developmental environment plays a very important role. Many people observe anger while growing up – it was thus part of their developmental environment. For them, it is appropriate behaviour in specific situations.

To understand this contribution from the developmental environment, a background in psychology is necessary.  The undergraduate degree in Behavioural Genetics at the UFS has Genetics and Psychology as majors, and this is where the link to genetic counselling comes in.

Murray explains that genetic counselling is a field in medical sciences focusing on helping patients affected by medical conditions to understand the underlying genetics.  For individuals with a family history of genetic conditions (such as specific cancers) or pregnant mothers with foetuses affected by genetic abnormalities (such as Down syndrome), the services of a genetic counsellor are invaluable.  A genetic counsellor will help these individuals understand the cause of the disorder, how it was diagnosed, what the symptoms are, what the progression will look like, if any treatment is available, and what the possible options are (if any) for alternatives.

Genetic counsellors need a strong background in both Genetics and Psychology. To become a registered genetic counsellor, a student completes a BSc degree in Biological Sciences (Behavioural Genetics at the UFS would be ideal).  Thereafter an honours degree in either Genetics or Psychology (though Genetics is preferable).  The student can then apply at either the University of the Witwatersrand or the University of Cape Town for a master’s degree in Genetic Counselling.  This entails two years of study, followed by two years of practical internship. Only after this you will be able to register with the Health Professions Council of South Africa (HPCSA) as a genetic counsellor.

Students studying Behavioural Genetics at the UFS are off to a great start. Murray’s teaching philosophy is to always strive to deliver students who are better than she is. “I can only really do this by sharing my passion for my research. I hope to inspire my students to also always be hungrily curious, to always question, and to find the joy in knowledge and learning.”

News Archive

UFS presents sport concussion programme for schools
2008-11-14

The Sports Medicine Clinic at the University of the Free State (UFS) will present a sports concussion programme for schools in the Free State.

“The Pharos Schools Concussion Programme makes the latest methods and technology in concussion management available to learners who play contact sport,” says Dr Louis Holtzhausen, Programme Director of Sports Medicine at the UFS.

The great risk of concussion is that there is an uncertainty about when a player can return to a sport with safety and with the minimum complications in the brain. This programme fills that gap to a large extent.

“By using this programme, no player who suffers concussion will return to play before it is medically safe to do so. The programme also educates players, parents, coaches and the medical fraternity on how to manage sports concussion,” says Dr Holtzhausen.

The programme has been designed for hockey, soccer, cricket, rugby and other contact and collision sports.

SA Rugby has used the programme for professional players for the last five years and advocates that all school rugby players should participate in the programme.

Several sports teams from schools in and around Bloemfontein as well as the University’s Shimla and Irawa rugby teams have already been tested. This will provide invaluable information in the management of possible head injuries.

“We can now give definite guidelines to players and coaches regarding the safe return of players to teams after such an injury. It takes a lot of the guesswork out of the management of concussion and provides peace of mind to coaches, parents and players regarding serious injuries,” says Dr Holtzhausen.

By enrolling in the concussion programme, learners and their parents are ensured of among others:

A baseline computer brain-function test before the start of the season.
Information on how to recognise and treat concussion, including a fieldside information card for the player’s team.
A free consultation and neurological examination by a sports physician after any suspected concussion.
As many brain-function tests and sports-physician consultations as necessary after any concussion, until complete recovery.
Referral to a network of specialists if necessary.

The Pharos Programme uses a cognitive function evaluation called Cogsport. This is a neurophysiological test that measures brain function before the season starts. In this way, a baseline standard is established and, should concussion occur during the season, the extent of it can be measured according to the baseline and rehabilitation.

“Once we have the baseline values, the concussed player’s return to those levels must be monitored. He/she can return to light exercise in the meantime and semi- and full-contact can be introduced at appropriate times,” says Dr Holtzhausen.

The cost of enrolment is R200 per learner, regardless of the number of concussions suffered or sports physician consultations received. “By enrolling in this programme, parents will ensure that their child has the best chance of avoiding the potentially serious consequences of concussion, including learning disabilities, recurrent concussions, epileptic fits and even death,” says Dr Holtzhausen.

More information on the programme can be obtained from Ms Arina Otto at 051 401 2530.

Media Release
Issued by: Lacea Loader
Assistant Director: Media Liaison
Tel: 051 401 2584
Cell: 083 645 2454
E-mail: loaderl.stg@ufs.ac.za  
14 November 2008
 

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