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15 June 2021 | Story Leonie Bolleurs | Photo Supplied
Zurika Murray says the study of Behavioural Genetics at the UFS focuses on human behaviour, specifically neurotransmitter systems, such as serotonin that may contribute to specific behavioural patterns.
Zurika Murray says the study of Behavioural Genetics at the UFS focuses on human behaviour, specifically neurotransmitter systems, such as serotonin that may contribute to specific behavioural patterns.

Hi. I am John. I have anger issues.

Just like John, there are thousands of South Africans with anger issues, often leading to violent crimes such as the more than 21 000 murder cases and 165 000 plus assault cases reported in 2020, according to a study by the South African Police Service and Statistics South Africa.

Aggression can be a great threat to society when it leads to violence. However, it can also be an absolute necessity when it leads to perseverance and a drive towards success and survival. This is according to Zurika Murray, a lecturer in the Department of Genetics at the University of the Free State (UFS), who is doing research on behavioural genetics.

 

Behavioural genetics

She explains behavioural genetics as a study of genetic variation contributing to how an organism interacts with and within its environment. “At the UFS, we focus on human behaviour, and specifically neurotransmitter systems, such as serotonin that may contribute to specific behavioural patterns.”

When one has the right amount of serotonin in your body, it is easier to have stable moods and a sense of well-being.

She says the neurotransmitter (which plays a role in, among others, emotional regulation) acts as a mediator, relaying messages and influencing response to environmental stimuli.  “This system is very adaptable, facilitating our functioning in an ever-changing emotional environment; but when dysfunctional, it can cause quite a number of abnormalities, from anxiety and depression to dysfunctional impulse control and violence. When some individuals are exposed to adverse developmental environments such as abuse and neglect, they can develop aggression and violence.”

“One of our current projects looks specifically at male juvenile delinquency and monoamine neurotransmitter systems (such as serotonin) that may contribute to specific characteristics (such as impulsivity) of delinquency.”

According to Murray, their research is also looking at the genetic variation within specific neurotransmitter genes to see if they could find similarities among individuals with similar developmental backgrounds.  “This neurotransmitter system additionally responds relatively well to physical activity as a management strategy for aggression in some individuals. We are looking at variations in this system that might explain this,” says Murray.

 

Genetic counselling

Apart from the genetic contribution, we also know that the developmental environment plays a very important role. Many people observe anger while growing up – it was thus part of their developmental environment. For them, it is appropriate behaviour in specific situations.

To understand this contribution from the developmental environment, a background in psychology is necessary.  The undergraduate degree in Behavioural Genetics at the UFS has Genetics and Psychology as majors, and this is where the link to genetic counselling comes in.

Murray explains that genetic counselling is a field in medical sciences focusing on helping patients affected by medical conditions to understand the underlying genetics.  For individuals with a family history of genetic conditions (such as specific cancers) or pregnant mothers with foetuses affected by genetic abnormalities (such as Down syndrome), the services of a genetic counsellor are invaluable.  A genetic counsellor will help these individuals understand the cause of the disorder, how it was diagnosed, what the symptoms are, what the progression will look like, if any treatment is available, and what the possible options are (if any) for alternatives.

Genetic counsellors need a strong background in both Genetics and Psychology. To become a registered genetic counsellor, a student completes a BSc degree in Biological Sciences (Behavioural Genetics at the UFS would be ideal).  Thereafter an honours degree in either Genetics or Psychology (though Genetics is preferable).  The student can then apply at either the University of the Witwatersrand or the University of Cape Town for a master’s degree in Genetic Counselling.  This entails two years of study, followed by two years of practical internship. Only after this you will be able to register with the Health Professions Council of South Africa (HPCSA) as a genetic counsellor.

Students studying Behavioural Genetics at the UFS are off to a great start. Murray’s teaching philosophy is to always strive to deliver students who are better than she is. “I can only really do this by sharing my passion for my research. I hope to inspire my students to also always be hungrily curious, to always question, and to find the joy in knowledge and learning.”

News Archive

Kovsies shine at USSA Cross Country Championships
2009-10-15

Thandi Malindi (far left) from the UFS and two Matie athletes, Elene Lourens and Mia Pienaar.
Photo: Supplied

Kovsie cross-country athletes Boy Soke and Thandi Malindi were included in the USSA squad for 2010 at the World Student Cross-Country Championships in Canada. The final team will be announced after the SA Cross-Country Championships. They recently participated in the USSA Cross-Country Championships that were held at the University of Johannesburg. According to Mr DB Prinsloo from KovsieSport at the University of the Free State, the UFS team did extremely well at the recent USSA Cross-Country Championships.

Kovsies won the women long-race team competition (8 km), while the men came second in the men’s long-race team (10 km) competition. In the short-race team competitions (4 km for men and women) the UFS men finished fourth and women ended in fifth place respectively.

Thandi Malindi, the UFS Women Cross-Country captain, was the first Kovsie over the line (third place), followed by Nelmarie Loubser (4th) and Maryna Swanepoel (6th), who also won the team competition in the 8 km (long race) with 13 penalty points against the 14 penalty points of the Maties who finished second.

Mr DB Prinsloo from KovsieSport at the UFS praised the Kovsie athletes for the manner in which they ran the race. “Thandi gave her all; so much so that she had to be admitted to hospital due to dehydration. Nelmaré ran the hills with a smile on her face and Maryna, who suffered from low blood sugar, persevered until the end so that a Matie athlete could not pass her. You all showed to us what ‘vasbyt’ really means,” Mr Prinsloo said.

Kovsies performed above expectation in the short race (4 km) for women. “Our women finished fifth in the team competition. If one takes into consideration that the Kovsies were represented by 400/800 athletes, i.e. Elri Richter (400/800), who came seventh, Anneri Ebersohn (400/400 hurdles), who ended in sixteenth place and Yvonne Eyssen (heptathlon) who ended in twentieth place, it makes this performance even better,” Mr Prinsloo commented.

In the men’s short race (4 km) where the Kovsies were represented by young first-year 800 m athletes, the UFS did excellently by finishing in fourth place. Hanne Naudé (18th), Lebohang Mpure (19th), Abri Horak (26th) and Gerrit Viljoen (34st) ran their hearts out!

The long race (10 km) for men, which was run on an extremely difficult course, was another highlight – also for the Kovsies. The Kovsies finished second in the team competition. Boy Soke (4th), Windy Jonas (8th), Schadrach Mochelenyane (10th) en Michael Tlhoro (21st) represented the Kovsies with honours. Unfortunately Johan Cronjé and Dumisane Hlaselo had to withdraw from the race due to injuries.

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