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15 June 2021 | Story Leonie Bolleurs | Photo Supplied
Zurika Murray says the study of Behavioural Genetics at the UFS focuses on human behaviour, specifically neurotransmitter systems, such as serotonin that may contribute to specific behavioural patterns.
Zurika Murray says the study of Behavioural Genetics at the UFS focuses on human behaviour, specifically neurotransmitter systems, such as serotonin that may contribute to specific behavioural patterns.

Hi. I am John. I have anger issues.

Just like John, there are thousands of South Africans with anger issues, often leading to violent crimes such as the more than 21 000 murder cases and 165 000 plus assault cases reported in 2020, according to a study by the South African Police Service and Statistics South Africa.

Aggression can be a great threat to society when it leads to violence. However, it can also be an absolute necessity when it leads to perseverance and a drive towards success and survival. This is according to Zurika Murray, a lecturer in the Department of Genetics at the University of the Free State (UFS), who is doing research on behavioural genetics.

 

Behavioural genetics

She explains behavioural genetics as a study of genetic variation contributing to how an organism interacts with and within its environment. “At the UFS, we focus on human behaviour, and specifically neurotransmitter systems, such as serotonin that may contribute to specific behavioural patterns.”

When one has the right amount of serotonin in your body, it is easier to have stable moods and a sense of well-being.

She says the neurotransmitter (which plays a role in, among others, emotional regulation) acts as a mediator, relaying messages and influencing response to environmental stimuli.  “This system is very adaptable, facilitating our functioning in an ever-changing emotional environment; but when dysfunctional, it can cause quite a number of abnormalities, from anxiety and depression to dysfunctional impulse control and violence. When some individuals are exposed to adverse developmental environments such as abuse and neglect, they can develop aggression and violence.”

“One of our current projects looks specifically at male juvenile delinquency and monoamine neurotransmitter systems (such as serotonin) that may contribute to specific characteristics (such as impulsivity) of delinquency.”

According to Murray, their research is also looking at the genetic variation within specific neurotransmitter genes to see if they could find similarities among individuals with similar developmental backgrounds.  “This neurotransmitter system additionally responds relatively well to physical activity as a management strategy for aggression in some individuals. We are looking at variations in this system that might explain this,” says Murray.

 

Genetic counselling

Apart from the genetic contribution, we also know that the developmental environment plays a very important role. Many people observe anger while growing up – it was thus part of their developmental environment. For them, it is appropriate behaviour in specific situations.

To understand this contribution from the developmental environment, a background in psychology is necessary.  The undergraduate degree in Behavioural Genetics at the UFS has Genetics and Psychology as majors, and this is where the link to genetic counselling comes in.

Murray explains that genetic counselling is a field in medical sciences focusing on helping patients affected by medical conditions to understand the underlying genetics.  For individuals with a family history of genetic conditions (such as specific cancers) or pregnant mothers with foetuses affected by genetic abnormalities (such as Down syndrome), the services of a genetic counsellor are invaluable.  A genetic counsellor will help these individuals understand the cause of the disorder, how it was diagnosed, what the symptoms are, what the progression will look like, if any treatment is available, and what the possible options are (if any) for alternatives.

Genetic counsellors need a strong background in both Genetics and Psychology. To become a registered genetic counsellor, a student completes a BSc degree in Biological Sciences (Behavioural Genetics at the UFS would be ideal).  Thereafter an honours degree in either Genetics or Psychology (though Genetics is preferable).  The student can then apply at either the University of the Witwatersrand or the University of Cape Town for a master’s degree in Genetic Counselling.  This entails two years of study, followed by two years of practical internship. Only after this you will be able to register with the Health Professions Council of South Africa (HPCSA) as a genetic counsellor.

Students studying Behavioural Genetics at the UFS are off to a great start. Murray’s teaching philosophy is to always strive to deliver students who are better than she is. “I can only really do this by sharing my passion for my research. I hope to inspire my students to also always be hungrily curious, to always question, and to find the joy in knowledge and learning.”

News Archive

UFS awards its innovative thinkers
2009-11-18

Here are, from the left: Prof. Van Wyk with first-prize winners Precious Setlaba and Themba Motsoeneng and Prof. Muriel Meiring, the students’ promoter.
Photo: Stephen Collett


The University of the Free State (UFS) recently announced the winners of the Innovation Fund Competition. This national competition, which is organised by the Department of Science and Technology aims to promote entrepreneurship through the commercialisation of the innovative ideas of young entrepreneurs.

Every participating educational institution first has an in-house competition in which a total prize money of R100 000 is at stake. At the UFS 14 business plans from students were received and evaluated by six external adjudicators. The three winners now have to take part in Phase II of the competition where 60 competitors from 20 universities will compete. The winners of the National Competition will receive prizes of up to R300 000. This money must be used for the development of the innovative idea with which the prize was won.

The first prize in the UFS’s Innovation Fund Competition of R50 000 was won by Themba Motsoeneng and Precious Setlaba from the Department of Haematology for the development of low-cost diagnostic assays for thrombotic diseases and bleeding disorders with the aim of supplying these test assays at a much lower cost to pathology laboratories all over the country. “This exciting idea appealed to many of the judges, especially because it can contribute to low cost health care in the country,” says Prof. Gerrit van Wyk, organiser of the Innovation Fund Competition at the UFS. The second prize of R30 000 was won by Charl Jaftha, MSc student in Physics. He has developed a low-cost hearing aid the size of a cigarette box. It contains a microphone and electronics to amplify the sound. The third prize of R20 000 was won by Adriaan Taylor and Jaco Brink, both MBA students. They designed a two-in-one lawnmower that would enable the average gardener with a bulky garden to shred the garden refuse and recycle it through composting or disposal through the normal disposal system. “One judge called this a novel use of existing technology,” says Prof. Van Wyk.
 

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