Latest News Archive

Please select Category, Year, and then Month to display items
Previous Archive
15 June 2021 | Story Leonie Bolleurs | Photo Supplied
Zurika Murray says the study of Behavioural Genetics at the UFS focuses on human behaviour, specifically neurotransmitter systems, such as serotonin that may contribute to specific behavioural patterns.
Zurika Murray says the study of Behavioural Genetics at the UFS focuses on human behaviour, specifically neurotransmitter systems, such as serotonin that may contribute to specific behavioural patterns.

Hi. I am John. I have anger issues.

Just like John, there are thousands of South Africans with anger issues, often leading to violent crimes such as the more than 21 000 murder cases and 165 000 plus assault cases reported in 2020, according to a study by the South African Police Service and Statistics South Africa.

Aggression can be a great threat to society when it leads to violence. However, it can also be an absolute necessity when it leads to perseverance and a drive towards success and survival. This is according to Zurika Murray, a lecturer in the Department of Genetics at the University of the Free State (UFS), who is doing research on behavioural genetics.

 

Behavioural genetics

She explains behavioural genetics as a study of genetic variation contributing to how an organism interacts with and within its environment. “At the UFS, we focus on human behaviour, and specifically neurotransmitter systems, such as serotonin that may contribute to specific behavioural patterns.”

When one has the right amount of serotonin in your body, it is easier to have stable moods and a sense of well-being.

She says the neurotransmitter (which plays a role in, among others, emotional regulation) acts as a mediator, relaying messages and influencing response to environmental stimuli.  “This system is very adaptable, facilitating our functioning in an ever-changing emotional environment; but when dysfunctional, it can cause quite a number of abnormalities, from anxiety and depression to dysfunctional impulse control and violence. When some individuals are exposed to adverse developmental environments such as abuse and neglect, they can develop aggression and violence.”

“One of our current projects looks specifically at male juvenile delinquency and monoamine neurotransmitter systems (such as serotonin) that may contribute to specific characteristics (such as impulsivity) of delinquency.”

According to Murray, their research is also looking at the genetic variation within specific neurotransmitter genes to see if they could find similarities among individuals with similar developmental backgrounds.  “This neurotransmitter system additionally responds relatively well to physical activity as a management strategy for aggression in some individuals. We are looking at variations in this system that might explain this,” says Murray.

 

Genetic counselling

Apart from the genetic contribution, we also know that the developmental environment plays a very important role. Many people observe anger while growing up – it was thus part of their developmental environment. For them, it is appropriate behaviour in specific situations.

To understand this contribution from the developmental environment, a background in psychology is necessary.  The undergraduate degree in Behavioural Genetics at the UFS has Genetics and Psychology as majors, and this is where the link to genetic counselling comes in.

Murray explains that genetic counselling is a field in medical sciences focusing on helping patients affected by medical conditions to understand the underlying genetics.  For individuals with a family history of genetic conditions (such as specific cancers) or pregnant mothers with foetuses affected by genetic abnormalities (such as Down syndrome), the services of a genetic counsellor are invaluable.  A genetic counsellor will help these individuals understand the cause of the disorder, how it was diagnosed, what the symptoms are, what the progression will look like, if any treatment is available, and what the possible options are (if any) for alternatives.

Genetic counsellors need a strong background in both Genetics and Psychology. To become a registered genetic counsellor, a student completes a BSc degree in Biological Sciences (Behavioural Genetics at the UFS would be ideal).  Thereafter an honours degree in either Genetics or Psychology (though Genetics is preferable).  The student can then apply at either the University of the Witwatersrand or the University of Cape Town for a master’s degree in Genetic Counselling.  This entails two years of study, followed by two years of practical internship. Only after this you will be able to register with the Health Professions Council of South Africa (HPCSA) as a genetic counsellor.

Students studying Behavioural Genetics at the UFS are off to a great start. Murray’s teaching philosophy is to always strive to deliver students who are better than she is. “I can only really do this by sharing my passion for my research. I hope to inspire my students to also always be hungrily curious, to always question, and to find the joy in knowledge and learning.”

News Archive

UFS scientists involved in groundbreaking research to protect rhino horns
2010-07-27

Pictured from the left are: Prof. Paul Grobler (UFS), Prof. Antoinette Kotze (NZG) and Ms. Karen Ehlers (UFS).
Photo: Supplied

Scientists at the University of the Free State (UFS) are involved in a research study that will help to trace the source of any southern white rhino product to a specific geographic location.

This is an initiative of the National Zoological Gardens of South Africa (NZG).

Prof. Paul Grobler, who is heading the project in the Department of Genetics at the UFS, said that the research might even allow the identification of the individual animal from which a product was derived. This would allow law enforcement agencies not only to determine with certainty whether rhino horn, traded illegally on the international black market, had its origin in South Africa, but also from which region of South Africa the product came.

This additional knowledge is expected to have a major impact on the illicit trade in rhino horn and provide a potent legal club to get at rhino horn smugglers and traders.

The full research team consists of Prof. Grobler; Christiaan Labuschagne, a Ph.D. student at the UFS; Prof. Antoinette Kotze from the NZG, who is also an affiliated professor at the UFS; and Dr Desire Dalton, also from the NZG.

The team’s research involves the identification of small differences in the genetic code among white rhino populations in different regions of South Africa. The genetic code of every species is unique, and is composed of a sequence of the four nucleotide bases G, A, T and C that are inherited from one generation to the next. When one nucleotide base is changed or mutated in an individual, this mutated base is also inherited by the individual's progeny.

If, after many generations, this changed base is present in at least 1% of the individuals of a group, it is described as a single nucleotide polymorphism (SNP), pronounced "snip". Breeding populations that are geographically and reproductively isolated often contain different patterns of such SNPs, which act as a unique genetic signature for each population.

The team is assembling a detailed list of all SNPs found in white rhinos from different regions in South Africa. The work is done in collaboration with the Pretoria-based company, Inqaba Biotech, who is performing the nucleotide sequencing that is required for the identification of the SNPs.

Financial support for the project is provided by the Advanced Biomolecular Research cluster at the UFS.

The southern white rhino was once thought to be extinct, but in a conservation success story the species was boosted from an initial population of about 100 individuals located in KwaZulu-Natal at the end of the 19th century, to the present population of about 15 000 individuals. The southern white rhino is still, however, listed as “near threatened” by the World Wildlife Fund (WWF).

Media Release:
Mangaliso Radebe
Assistant Director: Media Liaison
Tel: 051 401 2828
Cell: 078 460 3320
E-mail: radebemt@ufs.ac.za 
27 July 2010



 

We use cookies to make interactions with our websites and services easy and meaningful. To better understand how they are used, read more about the UFS cookie policy. By continuing to use this site you are giving us your consent to do this.

Accept