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15 June 2021 | Story Leonie Bolleurs | Photo Supplied
Zurika Murray says the study of Behavioural Genetics at the UFS focuses on human behaviour, specifically neurotransmitter systems, such as serotonin that may contribute to specific behavioural patterns.
Zurika Murray says the study of Behavioural Genetics at the UFS focuses on human behaviour, specifically neurotransmitter systems, such as serotonin that may contribute to specific behavioural patterns.

Hi. I am John. I have anger issues.

Just like John, there are thousands of South Africans with anger issues, often leading to violent crimes such as the more than 21 000 murder cases and 165 000 plus assault cases reported in 2020, according to a study by the South African Police Service and Statistics South Africa.

Aggression can be a great threat to society when it leads to violence. However, it can also be an absolute necessity when it leads to perseverance and a drive towards success and survival. This is according to Zurika Murray, a lecturer in the Department of Genetics at the University of the Free State (UFS), who is doing research on behavioural genetics.

 

Behavioural genetics

She explains behavioural genetics as a study of genetic variation contributing to how an organism interacts with and within its environment. “At the UFS, we focus on human behaviour, and specifically neurotransmitter systems, such as serotonin that may contribute to specific behavioural patterns.”

When one has the right amount of serotonin in your body, it is easier to have stable moods and a sense of well-being.

She says the neurotransmitter (which plays a role in, among others, emotional regulation) acts as a mediator, relaying messages and influencing response to environmental stimuli.  “This system is very adaptable, facilitating our functioning in an ever-changing emotional environment; but when dysfunctional, it can cause quite a number of abnormalities, from anxiety and depression to dysfunctional impulse control and violence. When some individuals are exposed to adverse developmental environments such as abuse and neglect, they can develop aggression and violence.”

“One of our current projects looks specifically at male juvenile delinquency and monoamine neurotransmitter systems (such as serotonin) that may contribute to specific characteristics (such as impulsivity) of delinquency.”

According to Murray, their research is also looking at the genetic variation within specific neurotransmitter genes to see if they could find similarities among individuals with similar developmental backgrounds.  “This neurotransmitter system additionally responds relatively well to physical activity as a management strategy for aggression in some individuals. We are looking at variations in this system that might explain this,” says Murray.

 

Genetic counselling

Apart from the genetic contribution, we also know that the developmental environment plays a very important role. Many people observe anger while growing up – it was thus part of their developmental environment. For them, it is appropriate behaviour in specific situations.

To understand this contribution from the developmental environment, a background in psychology is necessary.  The undergraduate degree in Behavioural Genetics at the UFS has Genetics and Psychology as majors, and this is where the link to genetic counselling comes in.

Murray explains that genetic counselling is a field in medical sciences focusing on helping patients affected by medical conditions to understand the underlying genetics.  For individuals with a family history of genetic conditions (such as specific cancers) or pregnant mothers with foetuses affected by genetic abnormalities (such as Down syndrome), the services of a genetic counsellor are invaluable.  A genetic counsellor will help these individuals understand the cause of the disorder, how it was diagnosed, what the symptoms are, what the progression will look like, if any treatment is available, and what the possible options are (if any) for alternatives.

Genetic counsellors need a strong background in both Genetics and Psychology. To become a registered genetic counsellor, a student completes a BSc degree in Biological Sciences (Behavioural Genetics at the UFS would be ideal).  Thereafter an honours degree in either Genetics or Psychology (though Genetics is preferable).  The student can then apply at either the University of the Witwatersrand or the University of Cape Town for a master’s degree in Genetic Counselling.  This entails two years of study, followed by two years of practical internship. Only after this you will be able to register with the Health Professions Council of South Africa (HPCSA) as a genetic counsellor.

Students studying Behavioural Genetics at the UFS are off to a great start. Murray’s teaching philosophy is to always strive to deliver students who are better than she is. “I can only really do this by sharing my passion for my research. I hope to inspire my students to also always be hungrily curious, to always question, and to find the joy in knowledge and learning.”

News Archive

UFS hosts the first Southern African Young Scientists Summer Programme
2012-11-26

The University of the Free State is to host the first Southern African Young Scientists Summer Programme (SA-YSSP) from 1 December 2012 to 28 February 2013. 

This will form part of an annual three-month education, academic training and research capacity-building programme jointly organised by the National Research Foundation (NRF), the Department of Science and Technology (DST), and the International Institute for Applied Systems Analysis (IIASA), based in Austria.
 
The NRF, as the National Member Organisation (NMO), in collaboration with DST, has developed a novel and innovative initiative with IIASA to establish the SA-YSSP. This programme was officially launched by the Minister of Science and Technology during November 2011.
 
IIASA is an international research organisation that conducts policy-oriented scientific research in the three global problem areas of energy and climate change, food and water and poverty and equity (www.iiasa.ac.at). South Africa’s engagements with IIASA, and specifically with regard to the SA-YSSP, relate primarily to the DST’s Ten-Year Innovation Plan.
 
Aligned with the YSSP model that is presented by IIASA in Austria annually, the SA-YSSP offers scientific seminars covering themes in both the social and natural sciences. These seminars often have policy dimensions and aim to broaden the participants’ perspectives and strengthen their analytical and modelling skills, further enriching a demanding academic and research programme (www.ufs.ac.za/sa-yssp).
 
Keynote lectures are to be delivered by national and international leaders in their respective research fields, partly drawn from IIASA’s widespread network of alumni and collaborators, as well as from the NRF’s extensive international networks of excellence.
 
The programme is to be enhanced with specific field trips and cultural and heritage excursions that will involve networking with locally based research programmes. Supervisory teams of both IIASA and South African experts will guide a cohort of competitively selected South African and international advanced Ph.D candidates.
 
The programme will be opened on 2 December 2012 at the Centenary Complex by the Minister of Science and Technology, Mr Derek Hanekom, the Director/CEO of IIASA, Prof Pavel Kabat and the Vice-Chancellor and Rector of the UFS, Prof Jonathan Jansen. They will be joined by a number of Nobel Prize Laureates and luminaries representing the government, the diplomatic sector and Higher Education.
 
The programme is directed by a multidisciplinary team at the UFS that includes:
Prof Aldo Stroebel and Prof Neil Roos (Co-Directors)
Prof André Roodt (Dean of SA-YSSP)
Prof Martin Ntwaeaborwa and Dr Henriëtte van den Berg (Deputy-Deans of SA-YSSP)
Dr Priscilla Mensah and Dr Sonja Loots (Strategic Managers)

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