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15 June 2021 | Story Leonie Bolleurs | Photo Supplied
Zurika Murray says the study of Behavioural Genetics at the UFS focuses on human behaviour, specifically neurotransmitter systems, such as serotonin that may contribute to specific behavioural patterns.
Zurika Murray says the study of Behavioural Genetics at the UFS focuses on human behaviour, specifically neurotransmitter systems, such as serotonin that may contribute to specific behavioural patterns.

Hi. I am John. I have anger issues.

Just like John, there are thousands of South Africans with anger issues, often leading to violent crimes such as the more than 21 000 murder cases and 165 000 plus assault cases reported in 2020, according to a study by the South African Police Service and Statistics South Africa.

Aggression can be a great threat to society when it leads to violence. However, it can also be an absolute necessity when it leads to perseverance and a drive towards success and survival. This is according to Zurika Murray, a lecturer in the Department of Genetics at the University of the Free State (UFS), who is doing research on behavioural genetics.

 

Behavioural genetics

She explains behavioural genetics as a study of genetic variation contributing to how an organism interacts with and within its environment. “At the UFS, we focus on human behaviour, and specifically neurotransmitter systems, such as serotonin that may contribute to specific behavioural patterns.”

When one has the right amount of serotonin in your body, it is easier to have stable moods and a sense of well-being.

She says the neurotransmitter (which plays a role in, among others, emotional regulation) acts as a mediator, relaying messages and influencing response to environmental stimuli.  “This system is very adaptable, facilitating our functioning in an ever-changing emotional environment; but when dysfunctional, it can cause quite a number of abnormalities, from anxiety and depression to dysfunctional impulse control and violence. When some individuals are exposed to adverse developmental environments such as abuse and neglect, they can develop aggression and violence.”

“One of our current projects looks specifically at male juvenile delinquency and monoamine neurotransmitter systems (such as serotonin) that may contribute to specific characteristics (such as impulsivity) of delinquency.”

According to Murray, their research is also looking at the genetic variation within specific neurotransmitter genes to see if they could find similarities among individuals with similar developmental backgrounds.  “This neurotransmitter system additionally responds relatively well to physical activity as a management strategy for aggression in some individuals. We are looking at variations in this system that might explain this,” says Murray.

 

Genetic counselling

Apart from the genetic contribution, we also know that the developmental environment plays a very important role. Many people observe anger while growing up – it was thus part of their developmental environment. For them, it is appropriate behaviour in specific situations.

To understand this contribution from the developmental environment, a background in psychology is necessary.  The undergraduate degree in Behavioural Genetics at the UFS has Genetics and Psychology as majors, and this is where the link to genetic counselling comes in.

Murray explains that genetic counselling is a field in medical sciences focusing on helping patients affected by medical conditions to understand the underlying genetics.  For individuals with a family history of genetic conditions (such as specific cancers) or pregnant mothers with foetuses affected by genetic abnormalities (such as Down syndrome), the services of a genetic counsellor are invaluable.  A genetic counsellor will help these individuals understand the cause of the disorder, how it was diagnosed, what the symptoms are, what the progression will look like, if any treatment is available, and what the possible options are (if any) for alternatives.

Genetic counsellors need a strong background in both Genetics and Psychology. To become a registered genetic counsellor, a student completes a BSc degree in Biological Sciences (Behavioural Genetics at the UFS would be ideal).  Thereafter an honours degree in either Genetics or Psychology (though Genetics is preferable).  The student can then apply at either the University of the Witwatersrand or the University of Cape Town for a master’s degree in Genetic Counselling.  This entails two years of study, followed by two years of practical internship. Only after this you will be able to register with the Health Professions Council of South Africa (HPCSA) as a genetic counsellor.

Students studying Behavioural Genetics at the UFS are off to a great start. Murray’s teaching philosophy is to always strive to deliver students who are better than she is. “I can only really do this by sharing my passion for my research. I hope to inspire my students to also always be hungrily curious, to always question, and to find the joy in knowledge and learning.”

News Archive

Researchers urged to re-emphasise regeneration of grassroots
2013-10-23

23 October 2013

Institutions of higher learning have a critical role to play in the promotion and protection of indigenous knowledge systems. This is according to Dr Mogomme Masoga, UFS alumnus and Senior Researcher with the Development Bank of Southern Africa (DBSA).

Dr Masoga was addressing the 6th annual Indigenous Knowledge Systems (IKS) Symposium at the University of the Free State’s Qwaqwa Campus.

“The time has come for local communities rich with knowledge to be taken seriously by the researchers doing their work in those respective communities,” argued Dr Masoga.

“Power relations between the researcher and the communities involved in the research process should be clarified. The same applies to the ownership and control of knowledge generated and documented in a community.

“There is an increasing need for democratic and participatory development in our communities. This can be achieved by giving primacy to the interests, values and aspirations of the people at large. There must be a radical move from prevailing paradigm of development that suffers from relying on coercion and authoritarianism. There is a need to associate development with social needs. This will give validity and integrity to the local communities, thereby giving confidence to the leaders and their constituencies.”

Dr Masoga said that the time has come for African universities in particular to “de-emphasise factors that monopolise attention today. Factors like debt crisis, commodity prices and foreign investment, among others, must be replaced by emphasis on the regeneration of the grassroots. Many African universities and research institutions have not lived up to their responsibilities as guiding lights to the continent. However, all is not lost.

“The current global race for knowledge works against so-called developing countries, especially in Africa. There is a far greater need to have a code of ethics drawn up for researchers engaging with local communities, to ensure the promotion and protection of indigenous knowledge systems.”

Meanwhile, a cross-section of papers were also delivered during the symposium. These ranged from Moshoeshoe’s lessons in dealing with poverty alleviation as presented by Dr Samuel Mensah, Department of Economics, to indigenous grasses of Qwaqwa by Prof Rodney Moffett, Department of Plant Sciences. Also presenting lectures were Phephani Gumbi, African Languages; Tshele Moloi, School of Mathematics; Natural Sciences and Technology Education and Dr Tom Ashafa (Plant Sciences).

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