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15 June 2021 | Story Leonie Bolleurs | Photo Supplied
Zurika Murray says the study of Behavioural Genetics at the UFS focuses on human behaviour, specifically neurotransmitter systems, such as serotonin that may contribute to specific behavioural patterns.
Zurika Murray says the study of Behavioural Genetics at the UFS focuses on human behaviour, specifically neurotransmitter systems, such as serotonin that may contribute to specific behavioural patterns.

Hi. I am John. I have anger issues.

Just like John, there are thousands of South Africans with anger issues, often leading to violent crimes such as the more than 21 000 murder cases and 165 000 plus assault cases reported in 2020, according to a study by the South African Police Service and Statistics South Africa.

Aggression can be a great threat to society when it leads to violence. However, it can also be an absolute necessity when it leads to perseverance and a drive towards success and survival. This is according to Zurika Murray, a lecturer in the Department of Genetics at the University of the Free State (UFS), who is doing research on behavioural genetics.

 

Behavioural genetics

She explains behavioural genetics as a study of genetic variation contributing to how an organism interacts with and within its environment. “At the UFS, we focus on human behaviour, and specifically neurotransmitter systems, such as serotonin that may contribute to specific behavioural patterns.”

When one has the right amount of serotonin in your body, it is easier to have stable moods and a sense of well-being.

She says the neurotransmitter (which plays a role in, among others, emotional regulation) acts as a mediator, relaying messages and influencing response to environmental stimuli.  “This system is very adaptable, facilitating our functioning in an ever-changing emotional environment; but when dysfunctional, it can cause quite a number of abnormalities, from anxiety and depression to dysfunctional impulse control and violence. When some individuals are exposed to adverse developmental environments such as abuse and neglect, they can develop aggression and violence.”

“One of our current projects looks specifically at male juvenile delinquency and monoamine neurotransmitter systems (such as serotonin) that may contribute to specific characteristics (such as impulsivity) of delinquency.”

According to Murray, their research is also looking at the genetic variation within specific neurotransmitter genes to see if they could find similarities among individuals with similar developmental backgrounds.  “This neurotransmitter system additionally responds relatively well to physical activity as a management strategy for aggression in some individuals. We are looking at variations in this system that might explain this,” says Murray.

 

Genetic counselling

Apart from the genetic contribution, we also know that the developmental environment plays a very important role. Many people observe anger while growing up – it was thus part of their developmental environment. For them, it is appropriate behaviour in specific situations.

To understand this contribution from the developmental environment, a background in psychology is necessary.  The undergraduate degree in Behavioural Genetics at the UFS has Genetics and Psychology as majors, and this is where the link to genetic counselling comes in.

Murray explains that genetic counselling is a field in medical sciences focusing on helping patients affected by medical conditions to understand the underlying genetics.  For individuals with a family history of genetic conditions (such as specific cancers) or pregnant mothers with foetuses affected by genetic abnormalities (such as Down syndrome), the services of a genetic counsellor are invaluable.  A genetic counsellor will help these individuals understand the cause of the disorder, how it was diagnosed, what the symptoms are, what the progression will look like, if any treatment is available, and what the possible options are (if any) for alternatives.

Genetic counsellors need a strong background in both Genetics and Psychology. To become a registered genetic counsellor, a student completes a BSc degree in Biological Sciences (Behavioural Genetics at the UFS would be ideal).  Thereafter an honours degree in either Genetics or Psychology (though Genetics is preferable).  The student can then apply at either the University of the Witwatersrand or the University of Cape Town for a master’s degree in Genetic Counselling.  This entails two years of study, followed by two years of practical internship. Only after this you will be able to register with the Health Professions Council of South Africa (HPCSA) as a genetic counsellor.

Students studying Behavioural Genetics at the UFS are off to a great start. Murray’s teaching philosophy is to always strive to deliver students who are better than she is. “I can only really do this by sharing my passion for my research. I hope to inspire my students to also always be hungrily curious, to always question, and to find the joy in knowledge and learning.”

News Archive

SA-YSSP scholars attend high level colloquium with policy makers and research stakeholders
2014-02-12

From the left are: Prof Frans Swanepoel, Deputy-Director of the African Doctoral Academy, Drs Aldo Stroebel, Executive Director: International Relations and Cooperation at the National Research Foundation, Priscilla Mensah, co-director of the SA-YSSP, and Ulf Dieckmann from the International Institute for Applied Systems Analysis and Dean of the SA-YSSP.
Photo: Renè-Jean van den Berg

Scholars taking part in the 2nd Southern African Young Scientists Summer Programme (SA-YSSP), attended a one-week seminar hosted by the African Doctoral Academy at the Stellenbosch University, which concluded with a colloquium at the Stellenbosch Institute for Advanced Study.

This was part of the final leg of their three-month stay and studies at the University of the Free State.

This seminar was a capacity development intervention with the purpose of equipping SA-YSSP young scholars with the skills to communicate their research work effectively with different audiences.

The 36 scholars were hand-picked from some of the world’s most promising and top researchers to take part in the novel three-month programme for advanced doctoral candidates. Their research interests closely aligned with the Department of Science and Technology’s (DST) grand challenges and the International Institute for Applied Systems Analysis’ (IIASA) current research programmes regarding global environmental, economic and social change.

The SA-YSSP is an initiative that contributes to the establishment, growth and enhancement of high-level strategic networks internationally. At the same time it develops capacity in systems analysis at the PhD and supervisory levels through research conducted in the areas of the Department of Science and Technology’s (DST) grand challenges.

At the colloquium, students were expected to showcase their work and research according to their various fields of expertise. High-profile policy makers and policy funders, as well as academia and fellow researchers judged and critiqued the work.

Dr Priscilla Mensah from the UFS and co-director of the programme, says it is important for the young scientists to frame their findings in a way that will be relevant to policy makers and the public at large.

“The partnership with the African Doctoral Academy was crucial in this regard since it is a capacity development entity aimed at strengthening and advancing doctoral education, training and scholarship on the African continent. The objective of this week-long capacity strengthening intervention is to equip the young scientists to be able to communicate their research effectively with different audiences, including potential funders and policy makers.

“I am convinced that the young scientists will no longer view policy makers as abstract entities, but as stakeholders who must be engaged to facilitate implementation of evidence-based policy.”

Dr Aldo Stroebel, Executive Director: International Relations and Cooperation, National Research Foundation, says the purpose of the colloquium is to bring together different sectors in one room to look at different challenges holistically, with an emphasis on systems analysis for a common goal.

The SA-YSSP forms part of an annual three-month education, academic training and research capacity-building programme jointly organised by IIASA, based in Austria, the National Research Foundation (NRF) and the DST. IIASA is an international research organisation that conducts policy-oriented scientific research in the three global problem areas of energy and climate change, food and water, and poverty and equity. South Africa’s engagements with IIASA, specifically with regard to the SA-YSSP, relate primarily to the DST’s Ten-Year Innovation Plan.

The UFS is the first institution outside Austria to host the summer programme. Researchers in the programme are, among others, from South Africa and the rest of the African continent, the USA, the Netherlands, India, Hungary, Austria and Germany.

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