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15 June 2021 | Story Leonie Bolleurs | Photo Supplied
Zurika Murray says the study of Behavioural Genetics at the UFS focuses on human behaviour, specifically neurotransmitter systems, such as serotonin that may contribute to specific behavioural patterns.
Zurika Murray says the study of Behavioural Genetics at the UFS focuses on human behaviour, specifically neurotransmitter systems, such as serotonin that may contribute to specific behavioural patterns.

Hi. I am John. I have anger issues.

Just like John, there are thousands of South Africans with anger issues, often leading to violent crimes such as the more than 21 000 murder cases and 165 000 plus assault cases reported in 2020, according to a study by the South African Police Service and Statistics South Africa.

Aggression can be a great threat to society when it leads to violence. However, it can also be an absolute necessity when it leads to perseverance and a drive towards success and survival. This is according to Zurika Murray, a lecturer in the Department of Genetics at the University of the Free State (UFS), who is doing research on behavioural genetics.

 

Behavioural genetics

She explains behavioural genetics as a study of genetic variation contributing to how an organism interacts with and within its environment. “At the UFS, we focus on human behaviour, and specifically neurotransmitter systems, such as serotonin that may contribute to specific behavioural patterns.”

When one has the right amount of serotonin in your body, it is easier to have stable moods and a sense of well-being.

She says the neurotransmitter (which plays a role in, among others, emotional regulation) acts as a mediator, relaying messages and influencing response to environmental stimuli.  “This system is very adaptable, facilitating our functioning in an ever-changing emotional environment; but when dysfunctional, it can cause quite a number of abnormalities, from anxiety and depression to dysfunctional impulse control and violence. When some individuals are exposed to adverse developmental environments such as abuse and neglect, they can develop aggression and violence.”

“One of our current projects looks specifically at male juvenile delinquency and monoamine neurotransmitter systems (such as serotonin) that may contribute to specific characteristics (such as impulsivity) of delinquency.”

According to Murray, their research is also looking at the genetic variation within specific neurotransmitter genes to see if they could find similarities among individuals with similar developmental backgrounds.  “This neurotransmitter system additionally responds relatively well to physical activity as a management strategy for aggression in some individuals. We are looking at variations in this system that might explain this,” says Murray.

 

Genetic counselling

Apart from the genetic contribution, we also know that the developmental environment plays a very important role. Many people observe anger while growing up – it was thus part of their developmental environment. For them, it is appropriate behaviour in specific situations.

To understand this contribution from the developmental environment, a background in psychology is necessary.  The undergraduate degree in Behavioural Genetics at the UFS has Genetics and Psychology as majors, and this is where the link to genetic counselling comes in.

Murray explains that genetic counselling is a field in medical sciences focusing on helping patients affected by medical conditions to understand the underlying genetics.  For individuals with a family history of genetic conditions (such as specific cancers) or pregnant mothers with foetuses affected by genetic abnormalities (such as Down syndrome), the services of a genetic counsellor are invaluable.  A genetic counsellor will help these individuals understand the cause of the disorder, how it was diagnosed, what the symptoms are, what the progression will look like, if any treatment is available, and what the possible options are (if any) for alternatives.

Genetic counsellors need a strong background in both Genetics and Psychology. To become a registered genetic counsellor, a student completes a BSc degree in Biological Sciences (Behavioural Genetics at the UFS would be ideal).  Thereafter an honours degree in either Genetics or Psychology (though Genetics is preferable).  The student can then apply at either the University of the Witwatersrand or the University of Cape Town for a master’s degree in Genetic Counselling.  This entails two years of study, followed by two years of practical internship. Only after this you will be able to register with the Health Professions Council of South Africa (HPCSA) as a genetic counsellor.

Students studying Behavioural Genetics at the UFS are off to a great start. Murray’s teaching philosophy is to always strive to deliver students who are better than she is. “I can only really do this by sharing my passion for my research. I hope to inspire my students to also always be hungrily curious, to always question, and to find the joy in knowledge and learning.”

News Archive

Prof Oriel Thekisoe receives prestigious TW Kambule NRF-NSTF Award
2014-07-07

 Prof Oriel Thekisoe
Photo: Sonia Small
Prof Oriel Thekisoe from the UFS was named recipient of the prestigious TW Kambule NRF-NSTF Award. The announcement was made during the 16th Annual NSTF-BHP Billiton 2013/2014 Awards Gala Dinner held in Johannesburg on Thursday 3 July 2014.

Prof Thekisoe is an Associate Professor in the university's Department of Zoology and Entomology at the Qwaqwa Campus.

He has been recognised as an emerging researcher for his outstanding contribution to Science, Engineering and Technology (SET).

"It is a great honour for the university to learn that Prof Thekisoe has won the award of the National Science and Technology Forum. This is a very competitive award and speaks of the quality and depth of talent at the UFS as we prepare the next generation of scientists and scholars,” said Vice-Chancellor and Rector of the UFS, Prof Jonathan Jansen.

"I hope that the award will inspire our current science students to work harder in pursuing the discovery of new methods and techniques which will improve our livelihoods,” Prof Thekisoe said after receiving the award from the Minister of Science and Technology, Ms Naledi Pandor. “I am grateful to the Dean of the Faculty of Natural and Agricultural Sciences, Prof Neil Heideman, for believing in me. I am also grateful to my former lecturers, Profs Peter Mbati, who is now the Rector of the University of Venda, and Noboru Inoue, from Japan’s Obihiro University, for grooming and inspiring the scientist in me.”

"Prof Thekisoe is at the forefront of the research development activities at the Qwaqwa Campus,” said Prof Corli Witthuhn, Vice-Rector: Research at the UFS. “He serves as a mentor to many of the younger scholars on the campus. As one of the Vice-Chancellor's Prestige Scholars at the university, he has the potential to become one of the most prominent researchers in his field in the country."

The Vice-Chancellor’s Prestige Programme (PSP) supports the accelerated scholarship of junior UFS researchers in the first five years after obtaining their PhDs. The prestige scholars participate in an intensive programme of support that includes international placement and intensive mentorship.

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