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15 June 2021 | Story Leonie Bolleurs | Photo Supplied
Zurika Murray says the study of Behavioural Genetics at the UFS focuses on human behaviour, specifically neurotransmitter systems, such as serotonin that may contribute to specific behavioural patterns.
Zurika Murray says the study of Behavioural Genetics at the UFS focuses on human behaviour, specifically neurotransmitter systems, such as serotonin that may contribute to specific behavioural patterns.

Hi. I am John. I have anger issues.

Just like John, there are thousands of South Africans with anger issues, often leading to violent crimes such as the more than 21 000 murder cases and 165 000 plus assault cases reported in 2020, according to a study by the South African Police Service and Statistics South Africa.

Aggression can be a great threat to society when it leads to violence. However, it can also be an absolute necessity when it leads to perseverance and a drive towards success and survival. This is according to Zurika Murray, a lecturer in the Department of Genetics at the University of the Free State (UFS), who is doing research on behavioural genetics.

 

Behavioural genetics

She explains behavioural genetics as a study of genetic variation contributing to how an organism interacts with and within its environment. “At the UFS, we focus on human behaviour, and specifically neurotransmitter systems, such as serotonin that may contribute to specific behavioural patterns.”

When one has the right amount of serotonin in your body, it is easier to have stable moods and a sense of well-being.

She says the neurotransmitter (which plays a role in, among others, emotional regulation) acts as a mediator, relaying messages and influencing response to environmental stimuli.  “This system is very adaptable, facilitating our functioning in an ever-changing emotional environment; but when dysfunctional, it can cause quite a number of abnormalities, from anxiety and depression to dysfunctional impulse control and violence. When some individuals are exposed to adverse developmental environments such as abuse and neglect, they can develop aggression and violence.”

“One of our current projects looks specifically at male juvenile delinquency and monoamine neurotransmitter systems (such as serotonin) that may contribute to specific characteristics (such as impulsivity) of delinquency.”

According to Murray, their research is also looking at the genetic variation within specific neurotransmitter genes to see if they could find similarities among individuals with similar developmental backgrounds.  “This neurotransmitter system additionally responds relatively well to physical activity as a management strategy for aggression in some individuals. We are looking at variations in this system that might explain this,” says Murray.

 

Genetic counselling

Apart from the genetic contribution, we also know that the developmental environment plays a very important role. Many people observe anger while growing up – it was thus part of their developmental environment. For them, it is appropriate behaviour in specific situations.

To understand this contribution from the developmental environment, a background in psychology is necessary.  The undergraduate degree in Behavioural Genetics at the UFS has Genetics and Psychology as majors, and this is where the link to genetic counselling comes in.

Murray explains that genetic counselling is a field in medical sciences focusing on helping patients affected by medical conditions to understand the underlying genetics.  For individuals with a family history of genetic conditions (such as specific cancers) or pregnant mothers with foetuses affected by genetic abnormalities (such as Down syndrome), the services of a genetic counsellor are invaluable.  A genetic counsellor will help these individuals understand the cause of the disorder, how it was diagnosed, what the symptoms are, what the progression will look like, if any treatment is available, and what the possible options are (if any) for alternatives.

Genetic counsellors need a strong background in both Genetics and Psychology. To become a registered genetic counsellor, a student completes a BSc degree in Biological Sciences (Behavioural Genetics at the UFS would be ideal).  Thereafter an honours degree in either Genetics or Psychology (though Genetics is preferable).  The student can then apply at either the University of the Witwatersrand or the University of Cape Town for a master’s degree in Genetic Counselling.  This entails two years of study, followed by two years of practical internship. Only after this you will be able to register with the Health Professions Council of South Africa (HPCSA) as a genetic counsellor.

Students studying Behavioural Genetics at the UFS are off to a great start. Murray’s teaching philosophy is to always strive to deliver students who are better than she is. “I can only really do this by sharing my passion for my research. I hope to inspire my students to also always be hungrily curious, to always question, and to find the joy in knowledge and learning.”

News Archive

UFS researcher runner-up in 2014 Women in Science Awards
2014-08-18

 

Prof Jeanet Conradie
Photo: Supplied

Prof Jeanet Conradie, professor in the Department of Chemistry at the University of the Free State (UFS), was the runner up in the senior category for Distinguished Women Researchers: Physical and Engineering Science in the Department of Science and Technology’s 2014 Women in Science Awards. With this award, female scientists and researchers are encouraged and rewarded, and also profiled as role models for younger women. 
 
Science and research, by which new concepts are discovered, is her great passion. Due to this keen interest in science, Prof Conradie studied a variety of subjects during her undergraduate years, providing her with a vast knowledge and the necessary background for her current main research interest, which is a combination of various scientific fields. Her PhD in Chemistry, as well as her strong background in Physics, Computer Science, Mathematics and Applied Maths, influenced her choice of research interest and expertise to gradually develop in the direction of computational chemistry, which is a beautiful combination of chemistry and physics. 
 
Today, Prof Conradie’s research expertise is in computational chemistry, using the super computer and appropriate software to simulate, understand and predict the behaviour of atoms and molecules in real life. The use of computational chemistry makes it possible to study chemical reactions and phenomena that are impossible or too dangerous to study experimentally. Her research team also performs experimental work in the laboratory to combine and compare with the computational analysis. Based on the results obtained, new materials with specific properties are developed. 
 
“We are very proud of Prof Conradie. This award is the result of 14 years of hard word, a lot of it after hours. We are fortunate to have someone like you as colleague who puts guidance to students and learners first in research, teaching and community service,” said Prof André Roodt, Head of the Department of Chemistry at the UFS. 
 
Prof Corli Witthuhn, Vice-Rector: Research said: “Prof Conradie serves as a role model for younger academic scholars in higher education through her motivation, productivity and drive. She also serves as an example of how female scientist can reach the top of their profession while juggling both professional and family responsibilities. This is well deserved recognition for her outstanding research achievements”

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