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15 June 2021 | Story Leonie Bolleurs | Photo Supplied
Zurika Murray says the study of Behavioural Genetics at the UFS focuses on human behaviour, specifically neurotransmitter systems, such as serotonin that may contribute to specific behavioural patterns.
Zurika Murray says the study of Behavioural Genetics at the UFS focuses on human behaviour, specifically neurotransmitter systems, such as serotonin that may contribute to specific behavioural patterns.

Hi. I am John. I have anger issues.

Just like John, there are thousands of South Africans with anger issues, often leading to violent crimes such as the more than 21 000 murder cases and 165 000 plus assault cases reported in 2020, according to a study by the South African Police Service and Statistics South Africa.

Aggression can be a great threat to society when it leads to violence. However, it can also be an absolute necessity when it leads to perseverance and a drive towards success and survival. This is according to Zurika Murray, a lecturer in the Department of Genetics at the University of the Free State (UFS), who is doing research on behavioural genetics.

 

Behavioural genetics

She explains behavioural genetics as a study of genetic variation contributing to how an organism interacts with and within its environment. “At the UFS, we focus on human behaviour, and specifically neurotransmitter systems, such as serotonin that may contribute to specific behavioural patterns.”

When one has the right amount of serotonin in your body, it is easier to have stable moods and a sense of well-being.

She says the neurotransmitter (which plays a role in, among others, emotional regulation) acts as a mediator, relaying messages and influencing response to environmental stimuli.  “This system is very adaptable, facilitating our functioning in an ever-changing emotional environment; but when dysfunctional, it can cause quite a number of abnormalities, from anxiety and depression to dysfunctional impulse control and violence. When some individuals are exposed to adverse developmental environments such as abuse and neglect, they can develop aggression and violence.”

“One of our current projects looks specifically at male juvenile delinquency and monoamine neurotransmitter systems (such as serotonin) that may contribute to specific characteristics (such as impulsivity) of delinquency.”

According to Murray, their research is also looking at the genetic variation within specific neurotransmitter genes to see if they could find similarities among individuals with similar developmental backgrounds.  “This neurotransmitter system additionally responds relatively well to physical activity as a management strategy for aggression in some individuals. We are looking at variations in this system that might explain this,” says Murray.

 

Genetic counselling

Apart from the genetic contribution, we also know that the developmental environment plays a very important role. Many people observe anger while growing up – it was thus part of their developmental environment. For them, it is appropriate behaviour in specific situations.

To understand this contribution from the developmental environment, a background in psychology is necessary.  The undergraduate degree in Behavioural Genetics at the UFS has Genetics and Psychology as majors, and this is where the link to genetic counselling comes in.

Murray explains that genetic counselling is a field in medical sciences focusing on helping patients affected by medical conditions to understand the underlying genetics.  For individuals with a family history of genetic conditions (such as specific cancers) or pregnant mothers with foetuses affected by genetic abnormalities (such as Down syndrome), the services of a genetic counsellor are invaluable.  A genetic counsellor will help these individuals understand the cause of the disorder, how it was diagnosed, what the symptoms are, what the progression will look like, if any treatment is available, and what the possible options are (if any) for alternatives.

Genetic counsellors need a strong background in both Genetics and Psychology. To become a registered genetic counsellor, a student completes a BSc degree in Biological Sciences (Behavioural Genetics at the UFS would be ideal).  Thereafter an honours degree in either Genetics or Psychology (though Genetics is preferable).  The student can then apply at either the University of the Witwatersrand or the University of Cape Town for a master’s degree in Genetic Counselling.  This entails two years of study, followed by two years of practical internship. Only after this you will be able to register with the Health Professions Council of South Africa (HPCSA) as a genetic counsellor.

Students studying Behavioural Genetics at the UFS are off to a great start. Murray’s teaching philosophy is to always strive to deliver students who are better than she is. “I can only really do this by sharing my passion for my research. I hope to inspire my students to also always be hungrily curious, to always question, and to find the joy in knowledge and learning.”

News Archive

Juan Odendaal on his way to World Champs
2015-03-23

Juan Odendaal
Photo: BOOGS Photography, Andrew McFadden

UFS’s athletes with disabilities are currently excelling in cycling and athletics.

The UFS Para-cyclist, Juan Odendaal, will soon make his debut for South Africa at the 2015 Union Cyclist International (UCI) Para-cycling Track World Championships in Apeldoorn, The Netherlands, from 26-29 March 2015.

The Championship event will provide an excellent foundation for re-building the international competitiveness of South Africa’s Para-cycling track team in the build-up to Rio 2016. In a situation where the UCI has hosted relatively few international track competitions over the past three years, the 2015 World Championships will serve as a stepping-stone to the 2016 grand season, when it is expected that the country’s top riders will reach their peak competitive condition.

As the youngest member of the South African team, Odendaal will use the opportunity of competing in the individual time trial and team sprint events to build a platform for an international career will certainly span many years to come.

Another UFS student, Musa Simelane, are excelling and was chosen for the SA Wheelchair Rugby tean, known as the "Wheelboks". They will compete in the 2015 World Wheelchair Rugby Challenge in London in October and after that head to Japan to compete in the 2015 Asia Oceania Championships.

On a local level, earlier in March this year, other UFS athletes with disabilities also performed well on the athletics track.

Blind athlete and member of the Bloemfontein Campus Student Representative Council (SRC), Louzanne Coetzee, also had a good 1500m race in the beginning of March when she qualified easily for the World Championships, which will take place in Toronto, Canada, later this year. Coetzee and her guide, Rouxné Jacobs, set up a time of 5:45.86, which is well under the required standard of 6 minutes.

The other blind UFS athlete, Danie Breitenbach, alongside his guide Marius Wessels, broke his own national record for the 800m again on Friday 6 March 2015. In November 2014, Breitenbach’s record stood at 2:15.17. This record now stands at 2:13.57. Chances now are that Breitenbach will reach his goal of running the 800m under 2:10 at the Nedbank National Championship for the Physically Disabled at the end of March 2015.

The other Kovsie stars who will be participating at the Nedbank National Championship for the Physically Disabled are as follows:

Athletes:
• Dineo Mokhosoa
• Louzanne Coetzee
• Danie Breitenbach
• Juanré Jenkinson
• Diederich Kleynhans
• Jacques de Bruyn

Swimmer:
• Johann van Heerden

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