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15 June 2021 | Story Leonie Bolleurs | Photo Supplied
Zurika Murray says the study of Behavioural Genetics at the UFS focuses on human behaviour, specifically neurotransmitter systems, such as serotonin that may contribute to specific behavioural patterns.
Zurika Murray says the study of Behavioural Genetics at the UFS focuses on human behaviour, specifically neurotransmitter systems, such as serotonin that may contribute to specific behavioural patterns.

Hi. I am John. I have anger issues.

Just like John, there are thousands of South Africans with anger issues, often leading to violent crimes such as the more than 21 000 murder cases and 165 000 plus assault cases reported in 2020, according to a study by the South African Police Service and Statistics South Africa.

Aggression can be a great threat to society when it leads to violence. However, it can also be an absolute necessity when it leads to perseverance and a drive towards success and survival. This is according to Zurika Murray, a lecturer in the Department of Genetics at the University of the Free State (UFS), who is doing research on behavioural genetics.

 

Behavioural genetics

She explains behavioural genetics as a study of genetic variation contributing to how an organism interacts with and within its environment. “At the UFS, we focus on human behaviour, and specifically neurotransmitter systems, such as serotonin that may contribute to specific behavioural patterns.”

When one has the right amount of serotonin in your body, it is easier to have stable moods and a sense of well-being.

She says the neurotransmitter (which plays a role in, among others, emotional regulation) acts as a mediator, relaying messages and influencing response to environmental stimuli.  “This system is very adaptable, facilitating our functioning in an ever-changing emotional environment; but when dysfunctional, it can cause quite a number of abnormalities, from anxiety and depression to dysfunctional impulse control and violence. When some individuals are exposed to adverse developmental environments such as abuse and neglect, they can develop aggression and violence.”

“One of our current projects looks specifically at male juvenile delinquency and monoamine neurotransmitter systems (such as serotonin) that may contribute to specific characteristics (such as impulsivity) of delinquency.”

According to Murray, their research is also looking at the genetic variation within specific neurotransmitter genes to see if they could find similarities among individuals with similar developmental backgrounds.  “This neurotransmitter system additionally responds relatively well to physical activity as a management strategy for aggression in some individuals. We are looking at variations in this system that might explain this,” says Murray.

 

Genetic counselling

Apart from the genetic contribution, we also know that the developmental environment plays a very important role. Many people observe anger while growing up – it was thus part of their developmental environment. For them, it is appropriate behaviour in specific situations.

To understand this contribution from the developmental environment, a background in psychology is necessary.  The undergraduate degree in Behavioural Genetics at the UFS has Genetics and Psychology as majors, and this is where the link to genetic counselling comes in.

Murray explains that genetic counselling is a field in medical sciences focusing on helping patients affected by medical conditions to understand the underlying genetics.  For individuals with a family history of genetic conditions (such as specific cancers) or pregnant mothers with foetuses affected by genetic abnormalities (such as Down syndrome), the services of a genetic counsellor are invaluable.  A genetic counsellor will help these individuals understand the cause of the disorder, how it was diagnosed, what the symptoms are, what the progression will look like, if any treatment is available, and what the possible options are (if any) for alternatives.

Genetic counsellors need a strong background in both Genetics and Psychology. To become a registered genetic counsellor, a student completes a BSc degree in Biological Sciences (Behavioural Genetics at the UFS would be ideal).  Thereafter an honours degree in either Genetics or Psychology (though Genetics is preferable).  The student can then apply at either the University of the Witwatersrand or the University of Cape Town for a master’s degree in Genetic Counselling.  This entails two years of study, followed by two years of practical internship. Only after this you will be able to register with the Health Professions Council of South Africa (HPCSA) as a genetic counsellor.

Students studying Behavioural Genetics at the UFS are off to a great start. Murray’s teaching philosophy is to always strive to deliver students who are better than she is. “I can only really do this by sharing my passion for my research. I hope to inspire my students to also always be hungrily curious, to always question, and to find the joy in knowledge and learning.”

News Archive

UFS Autumn Graduation inspires perseverance
2015-04-20

 

Louzanne Coetzee and her guide dog, Oakley after she received her degree at the UFS’s Autumn Graduation.
Photo: Gerhardus Bosch

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Prof Himla Soodyall
Mr Ndumiso Hadebe
Leanne Manas
Dr Maria Phalime
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Autumn has seen the UFS’s first graduation ceremonies of the year on the Bloemfontein Campus. From 14 to 17 April 2015, a total of 3 660 graduates were rewarded for their hard work while top speakers addressed them in the Callie Human Centre.

UFS Chancellor, Dr Khotso Mokhele, commented the more than 250 students who passed their degrees with distinctions at the autumn graduation.

Prof Soodyall, a Medical Scientist at the South African Institute for Medical Research as well as  Principal Medical Scientist for the National Health Laboratory Service, and Director for the Human Genome Diversity and Disease Research Unit at the University of Witwatersrand delivered the first motivational message of the April Graduation. The group of graduates in the Faculty of Natural and Agricultural Sciences listened as she shared her story with them.
 
"My own career – with no grand design or script – steered me into conducting genetic research on human populations from sub-Saharan Africa with a focus on a better understanding of human evolution, and to reconstruct the prehistory of African populations. While giving graduates a glimpse on how her career progressed, Prof Soodyall said: "I share these stories with you to give you some reassurance that you do not need feel that you have to figure out every minute detail of where to from here. Things fall into place with hard work, dedication, and dreams.

The developed world is forging ahead with interventions, so the gap between the developed world and the developing world continues to grow bigger. Prof Soodyall said: “You have the unenviable opportunity to think strategically, and to use the modern tools in your respective fields to make significant advances to transform our society, and to contribute to making it a better place for all. We need to embrace the current challenges, and build networks and bridges across disciplines to close the gaps, to work beyond the cultural barriers, and to ensure equity in access to health, water, education, etc, for all, as we would wish these things for ourselves and our families.

Read the full story of the Autumn Graduation 2015

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