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15 June 2021 | Story Leonie Bolleurs | Photo Supplied
Zurika Murray says the study of Behavioural Genetics at the UFS focuses on human behaviour, specifically neurotransmitter systems, such as serotonin that may contribute to specific behavioural patterns.
Zurika Murray says the study of Behavioural Genetics at the UFS focuses on human behaviour, specifically neurotransmitter systems, such as serotonin that may contribute to specific behavioural patterns.

Hi. I am John. I have anger issues.

Just like John, there are thousands of South Africans with anger issues, often leading to violent crimes such as the more than 21 000 murder cases and 165 000 plus assault cases reported in 2020, according to a study by the South African Police Service and Statistics South Africa.

Aggression can be a great threat to society when it leads to violence. However, it can also be an absolute necessity when it leads to perseverance and a drive towards success and survival. This is according to Zurika Murray, a lecturer in the Department of Genetics at the University of the Free State (UFS), who is doing research on behavioural genetics.

 

Behavioural genetics

She explains behavioural genetics as a study of genetic variation contributing to how an organism interacts with and within its environment. “At the UFS, we focus on human behaviour, and specifically neurotransmitter systems, such as serotonin that may contribute to specific behavioural patterns.”

When one has the right amount of serotonin in your body, it is easier to have stable moods and a sense of well-being.

She says the neurotransmitter (which plays a role in, among others, emotional regulation) acts as a mediator, relaying messages and influencing response to environmental stimuli.  “This system is very adaptable, facilitating our functioning in an ever-changing emotional environment; but when dysfunctional, it can cause quite a number of abnormalities, from anxiety and depression to dysfunctional impulse control and violence. When some individuals are exposed to adverse developmental environments such as abuse and neglect, they can develop aggression and violence.”

“One of our current projects looks specifically at male juvenile delinquency and monoamine neurotransmitter systems (such as serotonin) that may contribute to specific characteristics (such as impulsivity) of delinquency.”

According to Murray, their research is also looking at the genetic variation within specific neurotransmitter genes to see if they could find similarities among individuals with similar developmental backgrounds.  “This neurotransmitter system additionally responds relatively well to physical activity as a management strategy for aggression in some individuals. We are looking at variations in this system that might explain this,” says Murray.

 

Genetic counselling

Apart from the genetic contribution, we also know that the developmental environment plays a very important role. Many people observe anger while growing up – it was thus part of their developmental environment. For them, it is appropriate behaviour in specific situations.

To understand this contribution from the developmental environment, a background in psychology is necessary.  The undergraduate degree in Behavioural Genetics at the UFS has Genetics and Psychology as majors, and this is where the link to genetic counselling comes in.

Murray explains that genetic counselling is a field in medical sciences focusing on helping patients affected by medical conditions to understand the underlying genetics.  For individuals with a family history of genetic conditions (such as specific cancers) or pregnant mothers with foetuses affected by genetic abnormalities (such as Down syndrome), the services of a genetic counsellor are invaluable.  A genetic counsellor will help these individuals understand the cause of the disorder, how it was diagnosed, what the symptoms are, what the progression will look like, if any treatment is available, and what the possible options are (if any) for alternatives.

Genetic counsellors need a strong background in both Genetics and Psychology. To become a registered genetic counsellor, a student completes a BSc degree in Biological Sciences (Behavioural Genetics at the UFS would be ideal).  Thereafter an honours degree in either Genetics or Psychology (though Genetics is preferable).  The student can then apply at either the University of the Witwatersrand or the University of Cape Town for a master’s degree in Genetic Counselling.  This entails two years of study, followed by two years of practical internship. Only after this you will be able to register with the Health Professions Council of South Africa (HPCSA) as a genetic counsellor.

Students studying Behavioural Genetics at the UFS are off to a great start. Murray’s teaching philosophy is to always strive to deliver students who are better than she is. “I can only really do this by sharing my passion for my research. I hope to inspire my students to also always be hungrily curious, to always question, and to find the joy in knowledge and learning.”

News Archive

Plant-strengthening agent a result of joint effort between UFS and German company
2015-07-27

Research over the past few years has showed that the agent applied mostly as a foliar spray subsequently leads to better seedlings as well as growth and yield enhancement of various crops.

The application of a plant-strengthening agent in the agricultural industry has, until recently, been largely ignored, says Dr Elmarie van der Watt of the Department of Soil, Crop, and Climate Sciences at the University of the Free State (UFS). The agent was co-developed by researchers at the UFS and a German company.

The product is moving into new markets, such as China, Vietnam, the USA, and Australia.

ComCat® was the result of extensive research by the German company Agraforum AG. Commercialisation was limited initially to Europe, while research was expanded to other parts of the world, with the University of the Free State as the main research centre.  ComCat® is a unique, non-toxic plant strengthening agent derived from wild plants. It enhances plant growth and yield, as well as resistance against abiotic and biotic stress factors.

Dr Van der Watt says that, in nature, plants communicate and interact by means of allelochemicals (the inherent silent tool of self-protection among plants) and other phytochemicals (chemical compounds that occur naturally in plants), as part of their resistance mechanisms towards biotic and abiotic stress conditions.

Most wild-plant varieties are usually well-adapted to resist these stress factors. However, monoculture crops have lost this ability to a large extent. “Active compounds contained in extracts from wild plants applied to monoculture crops can potentially supply the signal for the latter to activate their dormant resistance mechanisms.” 

Research over the past few years has showed that the agent applied mostly as a foliar spray subsequently leads to better seedlings as well as growth and yield enhancement of various crops.  A major advantage is that, despite its enhancing effects on root development and yield, it does not induce unwanted early vegetative growth that could jeopardise the final yield, as happened in the past for nitrogen application at an early growth stage. 

Dr Van der Watt says, “Physiological data on the effect of the natural bio-stimulant product on photosynthesis, respiration, and resistance towards biotic stress conditions indicate that it can be regarded as a useful tool to manipulate agricultural crops. Research also showed that the field of application for this natural product is never-ending, and new applications are being investigated every day.”

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