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15 June 2021 | Story Leonie Bolleurs | Photo Supplied
Zurika Murray says the study of Behavioural Genetics at the UFS focuses on human behaviour, specifically neurotransmitter systems, such as serotonin that may contribute to specific behavioural patterns.
Zurika Murray says the study of Behavioural Genetics at the UFS focuses on human behaviour, specifically neurotransmitter systems, such as serotonin that may contribute to specific behavioural patterns.

Hi. I am John. I have anger issues.

Just like John, there are thousands of South Africans with anger issues, often leading to violent crimes such as the more than 21 000 murder cases and 165 000 plus assault cases reported in 2020, according to a study by the South African Police Service and Statistics South Africa.

Aggression can be a great threat to society when it leads to violence. However, it can also be an absolute necessity when it leads to perseverance and a drive towards success and survival. This is according to Zurika Murray, a lecturer in the Department of Genetics at the University of the Free State (UFS), who is doing research on behavioural genetics.

 

Behavioural genetics

She explains behavioural genetics as a study of genetic variation contributing to how an organism interacts with and within its environment. “At the UFS, we focus on human behaviour, and specifically neurotransmitter systems, such as serotonin that may contribute to specific behavioural patterns.”

When one has the right amount of serotonin in your body, it is easier to have stable moods and a sense of well-being.

She says the neurotransmitter (which plays a role in, among others, emotional regulation) acts as a mediator, relaying messages and influencing response to environmental stimuli.  “This system is very adaptable, facilitating our functioning in an ever-changing emotional environment; but when dysfunctional, it can cause quite a number of abnormalities, from anxiety and depression to dysfunctional impulse control and violence. When some individuals are exposed to adverse developmental environments such as abuse and neglect, they can develop aggression and violence.”

“One of our current projects looks specifically at male juvenile delinquency and monoamine neurotransmitter systems (such as serotonin) that may contribute to specific characteristics (such as impulsivity) of delinquency.”

According to Murray, their research is also looking at the genetic variation within specific neurotransmitter genes to see if they could find similarities among individuals with similar developmental backgrounds.  “This neurotransmitter system additionally responds relatively well to physical activity as a management strategy for aggression in some individuals. We are looking at variations in this system that might explain this,” says Murray.

 

Genetic counselling

Apart from the genetic contribution, we also know that the developmental environment plays a very important role. Many people observe anger while growing up – it was thus part of their developmental environment. For them, it is appropriate behaviour in specific situations.

To understand this contribution from the developmental environment, a background in psychology is necessary.  The undergraduate degree in Behavioural Genetics at the UFS has Genetics and Psychology as majors, and this is where the link to genetic counselling comes in.

Murray explains that genetic counselling is a field in medical sciences focusing on helping patients affected by medical conditions to understand the underlying genetics.  For individuals with a family history of genetic conditions (such as specific cancers) or pregnant mothers with foetuses affected by genetic abnormalities (such as Down syndrome), the services of a genetic counsellor are invaluable.  A genetic counsellor will help these individuals understand the cause of the disorder, how it was diagnosed, what the symptoms are, what the progression will look like, if any treatment is available, and what the possible options are (if any) for alternatives.

Genetic counsellors need a strong background in both Genetics and Psychology. To become a registered genetic counsellor, a student completes a BSc degree in Biological Sciences (Behavioural Genetics at the UFS would be ideal).  Thereafter an honours degree in either Genetics or Psychology (though Genetics is preferable).  The student can then apply at either the University of the Witwatersrand or the University of Cape Town for a master’s degree in Genetic Counselling.  This entails two years of study, followed by two years of practical internship. Only after this you will be able to register with the Health Professions Council of South Africa (HPCSA) as a genetic counsellor.

Students studying Behavioural Genetics at the UFS are off to a great start. Murray’s teaching philosophy is to always strive to deliver students who are better than she is. “I can only really do this by sharing my passion for my research. I hope to inspire my students to also always be hungrily curious, to always question, and to find the joy in knowledge and learning.”

News Archive

TEDxUFS conference - the highlight of the university’s innovative calendar
2015-08-11


Mmusi Maimane, leader of the Democratic Alliance with co-organisers of TEDxUFS Bonginkosi Leeuw and Lerothodi Molete after his inspirational talk at the event.
Photo: Curtis Nhlamulo Mashimbye

This year’s TEDxUFS speaker lineup persuaded the audience unanimously to question the nature of reality. The Albert Wessels Auditorium on the Bloemfontein Campus was packed with about 200 attendees on Saturday 1 August 2015.

Speakers shared a multiplicity of profound theories and inquisitions, challenging society in general to think out of the box. Melody Mentz, Gil Oved, Ricardo Peach, Pamela Nomvete, Pepe Marais, Mmusi Maimane, Brian Kally, Pieter Geldenhuys, Philippa Tumubweinee, Gareth Cliff, and Angelo Mockie took on to the stage to tackle multidisciplinary concepts as part of the broad ‘Ask Why’ theme.

Innovation mouthpieces share their worldview

Pieter Geldenhuys, the internationally-renowned futurist and Director of the Institute for Technology Strategy, and Innovation proposed that we change our mindsets by neglecting predictability. “We need to look at different models to understand the world around us,” he said. He challenged the linear and familiar ways humans make sense of the universe.

Speaking to the dire need for transformation, Philippa Tumubweinee suggested that university spaces merge with the communities they serve in terms of policies, social atmosphere, and physical structure. Tumubweinee is a senior Lecturer at the Department of Architecture at our university, and co-Founder and Director of Izuba In Africa architects.

“Only we can give permission to be intimidated; so don’t give in,” said Brian Kally, the CEO of Arrow Logistics (Pty) Ltd. Kally underscored the power of believing in our individual ideas.

Guidelines from TEDxUFS organisers

Bonginkosi Leeuw: “If you take your brainchild and implement it, and make it a reality, that’s when you can achieve great things, not before that.”

Lerothodi Molete: “You should ask questions; the moment you ask the question you will understand more.”

Real-time social media feedback

These are some of the comments audience members published on Twitter at the event:

IG: mispertanzy ?@MiesperTanzy  Aug 1

A huge shout-out to @TEDxUFS for hosting such a great conference!The team has really made the event an unmissable one on the UFS calendar.

Celebrabitur? ?@HatsuMphatsoe  Aug 1

Proximity that allows us to experience our broader society. Truly engaged by Philippa Tumbweinee's talk! @TEDxUFS

TEDxJohannesburg ?@TEDxJoburg  Aug 1

A big shoutout to @TEDxUFS from for a fantastic event. Wish we were there.

RicardoPeach ?@ricardopeach  Aug 1

Africa is rich with potential  #TEDXUFS @MmusiMaimane Yes!

 

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