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15 June 2021 | Story Leonie Bolleurs | Photo Supplied
Zurika Murray says the study of Behavioural Genetics at the UFS focuses on human behaviour, specifically neurotransmitter systems, such as serotonin that may contribute to specific behavioural patterns.
Zurika Murray says the study of Behavioural Genetics at the UFS focuses on human behaviour, specifically neurotransmitter systems, such as serotonin that may contribute to specific behavioural patterns.

Hi. I am John. I have anger issues.

Just like John, there are thousands of South Africans with anger issues, often leading to violent crimes such as the more than 21 000 murder cases and 165 000 plus assault cases reported in 2020, according to a study by the South African Police Service and Statistics South Africa.

Aggression can be a great threat to society when it leads to violence. However, it can also be an absolute necessity when it leads to perseverance and a drive towards success and survival. This is according to Zurika Murray, a lecturer in the Department of Genetics at the University of the Free State (UFS), who is doing research on behavioural genetics.

 

Behavioural genetics

She explains behavioural genetics as a study of genetic variation contributing to how an organism interacts with and within its environment. “At the UFS, we focus on human behaviour, and specifically neurotransmitter systems, such as serotonin that may contribute to specific behavioural patterns.”

When one has the right amount of serotonin in your body, it is easier to have stable moods and a sense of well-being.

She says the neurotransmitter (which plays a role in, among others, emotional regulation) acts as a mediator, relaying messages and influencing response to environmental stimuli.  “This system is very adaptable, facilitating our functioning in an ever-changing emotional environment; but when dysfunctional, it can cause quite a number of abnormalities, from anxiety and depression to dysfunctional impulse control and violence. When some individuals are exposed to adverse developmental environments such as abuse and neglect, they can develop aggression and violence.”

“One of our current projects looks specifically at male juvenile delinquency and monoamine neurotransmitter systems (such as serotonin) that may contribute to specific characteristics (such as impulsivity) of delinquency.”

According to Murray, their research is also looking at the genetic variation within specific neurotransmitter genes to see if they could find similarities among individuals with similar developmental backgrounds.  “This neurotransmitter system additionally responds relatively well to physical activity as a management strategy for aggression in some individuals. We are looking at variations in this system that might explain this,” says Murray.

 

Genetic counselling

Apart from the genetic contribution, we also know that the developmental environment plays a very important role. Many people observe anger while growing up – it was thus part of their developmental environment. For them, it is appropriate behaviour in specific situations.

To understand this contribution from the developmental environment, a background in psychology is necessary.  The undergraduate degree in Behavioural Genetics at the UFS has Genetics and Psychology as majors, and this is where the link to genetic counselling comes in.

Murray explains that genetic counselling is a field in medical sciences focusing on helping patients affected by medical conditions to understand the underlying genetics.  For individuals with a family history of genetic conditions (such as specific cancers) or pregnant mothers with foetuses affected by genetic abnormalities (such as Down syndrome), the services of a genetic counsellor are invaluable.  A genetic counsellor will help these individuals understand the cause of the disorder, how it was diagnosed, what the symptoms are, what the progression will look like, if any treatment is available, and what the possible options are (if any) for alternatives.

Genetic counsellors need a strong background in both Genetics and Psychology. To become a registered genetic counsellor, a student completes a BSc degree in Biological Sciences (Behavioural Genetics at the UFS would be ideal).  Thereafter an honours degree in either Genetics or Psychology (though Genetics is preferable).  The student can then apply at either the University of the Witwatersrand or the University of Cape Town for a master’s degree in Genetic Counselling.  This entails two years of study, followed by two years of practical internship. Only after this you will be able to register with the Health Professions Council of South Africa (HPCSA) as a genetic counsellor.

Students studying Behavioural Genetics at the UFS are off to a great start. Murray’s teaching philosophy is to always strive to deliver students who are better than she is. “I can only really do this by sharing my passion for my research. I hope to inspire my students to also always be hungrily curious, to always question, and to find the joy in knowledge and learning.”

News Archive

UFS launches expansions to Biotechnology Building
2015-11-04

     

Biotechnology Building
Photo: Leonie Bolleurs

To support the strategic focus of the University of the Free State (UFS) on teaching and learning in the field of Biotechnology, the Department of Microbial, Biochemical, and Food Biotechnology introduced upgrades and additions to the value of R23 million to the existing Biotechnology Building on its Bloemfontein Campus. The funding was provided by the Department of Higher Education and Training.

The new section, together with renovations to the existing part of the Biotechnology Building, was opened on Thursday 29 October 2015.

The Department, consisting of three disciplines - Microbiology, Biochemistry, and Food Biotechnology - is extremely diverse. Two of the three disciplines – Microbiology and Biochemistry – are housed in the Biotechnology Building.

Additions and renovations to the Biotechnology Building include:
-    Four new research laboratories
-    Nine revamped research laboratories

      

At the launch of the Biotechnology Building were,
from the left: Nico Janse van Rensburg,
Senior Director: University Estates;
Maureen Khati, University Estates,
Prof Nicky Morgan, Vice Rector: Operations
and Ria Deysel, Director: Facilities Management.
Photo: Leonie Bolleurs

The work to the building will have dramatic effects on the quality, as well as the quantity, of postgraduate students. Given the national priority to deliver students, this is very important, particularly at the doctorate level.

Prof Koos Albertyn from the Department said these were the first renovations and expansions done to the building since 1 January 1990. “We welcome the extra space. Forty-six more postgraduate students can now be accommodated in the department,” he said.

Construction took place on the south-western corner of the existing building. Further developments to the building include:
-    Six new offices
-    A lecture hall for 70 students
-    Laboratories that can accommodate 56 postgraduate students

Prof Martie Smit, Academic Head of the Department, said: “This new and refurbished facility enables us to give our best. As academics, we are committed to doing our part in delivering high-quality education at both undergraduate and postgraduate levels to students envisaging a future in biotechnology.”

The James Charles du Preez Seminar Room was also opened at the event. The seminar room is dedicated to Prof Du Preez – who was Head of the Department from October 2002 until the end of 2014. He played a major role in raising funds for upgrading the Biotechnology Building, including the addition of a new wing.



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