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15 June 2021 | Story Leonie Bolleurs | Photo Supplied
Zurika Murray says the study of Behavioural Genetics at the UFS focuses on human behaviour, specifically neurotransmitter systems, such as serotonin that may contribute to specific behavioural patterns.
Zurika Murray says the study of Behavioural Genetics at the UFS focuses on human behaviour, specifically neurotransmitter systems, such as serotonin that may contribute to specific behavioural patterns.

Hi. I am John. I have anger issues.

Just like John, there are thousands of South Africans with anger issues, often leading to violent crimes such as the more than 21 000 murder cases and 165 000 plus assault cases reported in 2020, according to a study by the South African Police Service and Statistics South Africa.

Aggression can be a great threat to society when it leads to violence. However, it can also be an absolute necessity when it leads to perseverance and a drive towards success and survival. This is according to Zurika Murray, a lecturer in the Department of Genetics at the University of the Free State (UFS), who is doing research on behavioural genetics.

 

Behavioural genetics

She explains behavioural genetics as a study of genetic variation contributing to how an organism interacts with and within its environment. “At the UFS, we focus on human behaviour, and specifically neurotransmitter systems, such as serotonin that may contribute to specific behavioural patterns.”

When one has the right amount of serotonin in your body, it is easier to have stable moods and a sense of well-being.

She says the neurotransmitter (which plays a role in, among others, emotional regulation) acts as a mediator, relaying messages and influencing response to environmental stimuli.  “This system is very adaptable, facilitating our functioning in an ever-changing emotional environment; but when dysfunctional, it can cause quite a number of abnormalities, from anxiety and depression to dysfunctional impulse control and violence. When some individuals are exposed to adverse developmental environments such as abuse and neglect, they can develop aggression and violence.”

“One of our current projects looks specifically at male juvenile delinquency and monoamine neurotransmitter systems (such as serotonin) that may contribute to specific characteristics (such as impulsivity) of delinquency.”

According to Murray, their research is also looking at the genetic variation within specific neurotransmitter genes to see if they could find similarities among individuals with similar developmental backgrounds.  “This neurotransmitter system additionally responds relatively well to physical activity as a management strategy for aggression in some individuals. We are looking at variations in this system that might explain this,” says Murray.

 

Genetic counselling

Apart from the genetic contribution, we also know that the developmental environment plays a very important role. Many people observe anger while growing up – it was thus part of their developmental environment. For them, it is appropriate behaviour in specific situations.

To understand this contribution from the developmental environment, a background in psychology is necessary.  The undergraduate degree in Behavioural Genetics at the UFS has Genetics and Psychology as majors, and this is where the link to genetic counselling comes in.

Murray explains that genetic counselling is a field in medical sciences focusing on helping patients affected by medical conditions to understand the underlying genetics.  For individuals with a family history of genetic conditions (such as specific cancers) or pregnant mothers with foetuses affected by genetic abnormalities (such as Down syndrome), the services of a genetic counsellor are invaluable.  A genetic counsellor will help these individuals understand the cause of the disorder, how it was diagnosed, what the symptoms are, what the progression will look like, if any treatment is available, and what the possible options are (if any) for alternatives.

Genetic counsellors need a strong background in both Genetics and Psychology. To become a registered genetic counsellor, a student completes a BSc degree in Biological Sciences (Behavioural Genetics at the UFS would be ideal).  Thereafter an honours degree in either Genetics or Psychology (though Genetics is preferable).  The student can then apply at either the University of the Witwatersrand or the University of Cape Town for a master’s degree in Genetic Counselling.  This entails two years of study, followed by two years of practical internship. Only after this you will be able to register with the Health Professions Council of South Africa (HPCSA) as a genetic counsellor.

Students studying Behavioural Genetics at the UFS are off to a great start. Murray’s teaching philosophy is to always strive to deliver students who are better than she is. “I can only really do this by sharing my passion for my research. I hope to inspire my students to also always be hungrily curious, to always question, and to find the joy in knowledge and learning.”

News Archive

Linguistic resourcefulness impresses at 15th Student Symposium on the Natural Sciences
2015-11-26


UFS students walk away with more than half the prizes at this year’s Student Symposium on the Natural Sciences.

This year, the fifteenth annual Student Symposium on the Natural Sciences was hosted on the Bloemfontein Campus by the UFS Departments of Chemistry and Physics, together with the South African Academy for Science and Arts (SAAWK).

According to Dr Ernie Langner, Senior Lecturer in the Department of Chemistry, this symposium provides postgraduate students from all over South Africa the opportunity to present their research in Afrikaans, to learn from each other, receive feedback on their work through the review process, and to build networks. If their abstracts are selected for publication in the Suid-Afrikaanse Tydskrif vir Natuurwetenskap en Tegnologie, it also provides them with further exposure in the broader academic context.

Besides research of the highest quality, this year's symposium had no shortage of linguistic resourcefulness. “Students, accustomed to writing and expressing their research in English, astonished everybody with their beautiful Afrikaans. Outstanding research from honours, master's, and doctoral students was expressed in scientific terminology of the highest standard,” Dr Langner said.

The Student Symposium is the only event (worldwide) where the development of 'elektrostatiese potensiaalkaarte', 'femtosekonde pomp-proef spektroskopie', or 'endokrien-ontwrigtende chemikalieë' is explained step by step. This is where one hears enthusiastic students talking about how hard they are working on 'geïntegreerde drywende sonkragstelsels', or 'geneste virtuele rekenaars binne die wolkstelsel'. The results of hours of hard work in the lab, cold nights behind a telescope, or long midnight sessions in front of the computer, had to be condensed into 15-minute presentations on the synthesis of metal-organic networks, or metal-carbene complexes, the identification of pulsar rhythms, or the refining of rapid-eye technology.

Of approximately forty participants from five universities, eighteen were awarded prizes for their papers and posters. Students from the UFS walked away with more than half of the awards. Jacques Maritz (Physics) and his wife, Elizabeth, (Mathematics and Applied Mathematics) from the UFS were both awarded first place in their respective sessions.

 

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