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15 June 2021 | Story Leonie Bolleurs | Photo Supplied
Zurika Murray says the study of Behavioural Genetics at the UFS focuses on human behaviour, specifically neurotransmitter systems, such as serotonin that may contribute to specific behavioural patterns.
Zurika Murray says the study of Behavioural Genetics at the UFS focuses on human behaviour, specifically neurotransmitter systems, such as serotonin that may contribute to specific behavioural patterns.

Hi. I am John. I have anger issues.

Just like John, there are thousands of South Africans with anger issues, often leading to violent crimes such as the more than 21 000 murder cases and 165 000 plus assault cases reported in 2020, according to a study by the South African Police Service and Statistics South Africa.

Aggression can be a great threat to society when it leads to violence. However, it can also be an absolute necessity when it leads to perseverance and a drive towards success and survival. This is according to Zurika Murray, a lecturer in the Department of Genetics at the University of the Free State (UFS), who is doing research on behavioural genetics.

 

Behavioural genetics

She explains behavioural genetics as a study of genetic variation contributing to how an organism interacts with and within its environment. “At the UFS, we focus on human behaviour, and specifically neurotransmitter systems, such as serotonin that may contribute to specific behavioural patterns.”

When one has the right amount of serotonin in your body, it is easier to have stable moods and a sense of well-being.

She says the neurotransmitter (which plays a role in, among others, emotional regulation) acts as a mediator, relaying messages and influencing response to environmental stimuli.  “This system is very adaptable, facilitating our functioning in an ever-changing emotional environment; but when dysfunctional, it can cause quite a number of abnormalities, from anxiety and depression to dysfunctional impulse control and violence. When some individuals are exposed to adverse developmental environments such as abuse and neglect, they can develop aggression and violence.”

“One of our current projects looks specifically at male juvenile delinquency and monoamine neurotransmitter systems (such as serotonin) that may contribute to specific characteristics (such as impulsivity) of delinquency.”

According to Murray, their research is also looking at the genetic variation within specific neurotransmitter genes to see if they could find similarities among individuals with similar developmental backgrounds.  “This neurotransmitter system additionally responds relatively well to physical activity as a management strategy for aggression in some individuals. We are looking at variations in this system that might explain this,” says Murray.

 

Genetic counselling

Apart from the genetic contribution, we also know that the developmental environment plays a very important role. Many people observe anger while growing up – it was thus part of their developmental environment. For them, it is appropriate behaviour in specific situations.

To understand this contribution from the developmental environment, a background in psychology is necessary.  The undergraduate degree in Behavioural Genetics at the UFS has Genetics and Psychology as majors, and this is where the link to genetic counselling comes in.

Murray explains that genetic counselling is a field in medical sciences focusing on helping patients affected by medical conditions to understand the underlying genetics.  For individuals with a family history of genetic conditions (such as specific cancers) or pregnant mothers with foetuses affected by genetic abnormalities (such as Down syndrome), the services of a genetic counsellor are invaluable.  A genetic counsellor will help these individuals understand the cause of the disorder, how it was diagnosed, what the symptoms are, what the progression will look like, if any treatment is available, and what the possible options are (if any) for alternatives.

Genetic counsellors need a strong background in both Genetics and Psychology. To become a registered genetic counsellor, a student completes a BSc degree in Biological Sciences (Behavioural Genetics at the UFS would be ideal).  Thereafter an honours degree in either Genetics or Psychology (though Genetics is preferable).  The student can then apply at either the University of the Witwatersrand or the University of Cape Town for a master’s degree in Genetic Counselling.  This entails two years of study, followed by two years of practical internship. Only after this you will be able to register with the Health Professions Council of South Africa (HPCSA) as a genetic counsellor.

Students studying Behavioural Genetics at the UFS are off to a great start. Murray’s teaching philosophy is to always strive to deliver students who are better than she is. “I can only really do this by sharing my passion for my research. I hope to inspire my students to also always be hungrily curious, to always question, and to find the joy in knowledge and learning.”

News Archive

Researcher in Otorhinolaryngology advocates education in deafness and hearing loss
2015-12-17

Description: Dr Magteld Smith  Tags: Dr Magteld Smith

Dr Magteld Smith

The annual International Day of Persons with Disabilities falls on 3 December. Statistics reveal that 7.5% of the South African population suffer from some form of physical disability.

More than 17 million people in South Africa are dealing with depression, substance abuse, anxiety, bipolar disorder, and schizophrenia - illnesses that round out the top five mental health diagnoses, according to the Mental Health Federation of South Africa. The South African Federation for Mental Health is the umbrella body for 17 mental health societies and numerous member organisations throughout the country.

On disability, world-renowned author Helen Keller, who was both deaf and blind, once said that the problems that come with being deaf are deeper and more complex than those of blindness, and is a much worse misfortune. For it means the loss of the most vital stimulus - the sound of the voice that brings language, sets thoughts astir, and keeps us in the intellectual company of man.

According to Dr Magteld Smith, lecturer and researcher in the Department of Otorhinolaryngology at the University of the Free State (UFS), hearing loss of any degree at any age can have far-reaching psychological and sociological implications which affect an individual’s day-to-day functioning, and might prevent him or her from reaching their full potential. She says that even though advancements have been made in aiding deaf persons, there’s still considerable room for improvement. She’s making it her mission to bring about changing the stigmatisation around deafness, and the different choices of rehabilitation.

Dr Smith was born with bilateral (both ears) severe hearing loss, and became profoundly deaf, receiving a cochlear implant in 2008. Not letting this hinder her quality of life, she matriculated in 1985 at a School for the Deaf in Worcester. Today she is the only deaf medical-social researcher in South Africa.

Her research focuses on all aspects of deafness and hearing loss. Through first-hand experience, she knows that a loss of hearing can be traumatic as it requires adjustments in many areas of life which affect a person’s entire development. However, she has not let her deafness become a stumbling block. She has become the first deaf South African to obtain two Master’s degrees and a PhD, together with various other achievements.

Her work is aimed at informing and educating people in the medical profession, parents with children, and persons with various degrees and types of hearing loss about the complexities of deafness and hearing loss. She believes that, with the technological advancements that have been made in the world, deaf people can become self-sufficient and independent world changers with much to contribute to humanity.

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