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15 June 2021 | Story Leonie Bolleurs | Photo Supplied
Zurika Murray says the study of Behavioural Genetics at the UFS focuses on human behaviour, specifically neurotransmitter systems, such as serotonin that may contribute to specific behavioural patterns.
Zurika Murray says the study of Behavioural Genetics at the UFS focuses on human behaviour, specifically neurotransmitter systems, such as serotonin that may contribute to specific behavioural patterns.

Hi. I am John. I have anger issues.

Just like John, there are thousands of South Africans with anger issues, often leading to violent crimes such as the more than 21 000 murder cases and 165 000 plus assault cases reported in 2020, according to a study by the South African Police Service and Statistics South Africa.

Aggression can be a great threat to society when it leads to violence. However, it can also be an absolute necessity when it leads to perseverance and a drive towards success and survival. This is according to Zurika Murray, a lecturer in the Department of Genetics at the University of the Free State (UFS), who is doing research on behavioural genetics.

 

Behavioural genetics

She explains behavioural genetics as a study of genetic variation contributing to how an organism interacts with and within its environment. “At the UFS, we focus on human behaviour, and specifically neurotransmitter systems, such as serotonin that may contribute to specific behavioural patterns.”

When one has the right amount of serotonin in your body, it is easier to have stable moods and a sense of well-being.

She says the neurotransmitter (which plays a role in, among others, emotional regulation) acts as a mediator, relaying messages and influencing response to environmental stimuli.  “This system is very adaptable, facilitating our functioning in an ever-changing emotional environment; but when dysfunctional, it can cause quite a number of abnormalities, from anxiety and depression to dysfunctional impulse control and violence. When some individuals are exposed to adverse developmental environments such as abuse and neglect, they can develop aggression and violence.”

“One of our current projects looks specifically at male juvenile delinquency and monoamine neurotransmitter systems (such as serotonin) that may contribute to specific characteristics (such as impulsivity) of delinquency.”

According to Murray, their research is also looking at the genetic variation within specific neurotransmitter genes to see if they could find similarities among individuals with similar developmental backgrounds.  “This neurotransmitter system additionally responds relatively well to physical activity as a management strategy for aggression in some individuals. We are looking at variations in this system that might explain this,” says Murray.

 

Genetic counselling

Apart from the genetic contribution, we also know that the developmental environment plays a very important role. Many people observe anger while growing up – it was thus part of their developmental environment. For them, it is appropriate behaviour in specific situations.

To understand this contribution from the developmental environment, a background in psychology is necessary.  The undergraduate degree in Behavioural Genetics at the UFS has Genetics and Psychology as majors, and this is where the link to genetic counselling comes in.

Murray explains that genetic counselling is a field in medical sciences focusing on helping patients affected by medical conditions to understand the underlying genetics.  For individuals with a family history of genetic conditions (such as specific cancers) or pregnant mothers with foetuses affected by genetic abnormalities (such as Down syndrome), the services of a genetic counsellor are invaluable.  A genetic counsellor will help these individuals understand the cause of the disorder, how it was diagnosed, what the symptoms are, what the progression will look like, if any treatment is available, and what the possible options are (if any) for alternatives.

Genetic counsellors need a strong background in both Genetics and Psychology. To become a registered genetic counsellor, a student completes a BSc degree in Biological Sciences (Behavioural Genetics at the UFS would be ideal).  Thereafter an honours degree in either Genetics or Psychology (though Genetics is preferable).  The student can then apply at either the University of the Witwatersrand or the University of Cape Town for a master’s degree in Genetic Counselling.  This entails two years of study, followed by two years of practical internship. Only after this you will be able to register with the Health Professions Council of South Africa (HPCSA) as a genetic counsellor.

Students studying Behavioural Genetics at the UFS are off to a great start. Murray’s teaching philosophy is to always strive to deliver students who are better than she is. “I can only really do this by sharing my passion for my research. I hope to inspire my students to also always be hungrily curious, to always question, and to find the joy in knowledge and learning.”

News Archive

Shimlas shock Tuks by staying calm
2016-02-19

Description: KL News 2016 02 19  Varsitycup Tags: KL News 2016 02 19  Varsitycup
Prop Ox Nche was one of the substitutes who had a huge impact against Tuks in Pretoria on 15 February 2016. Nche and other Shimlas substitutes helped their team wipe out a massive deficit. Photo: Johan Roux.

He has never been involved in a match like this in his rugby career.
This is what Neil Claassen had to say about his team’s performance on 15 February 2016, when the Shimlas came up with one of the biggest fight-backs in the history of the Varsity Cup in Pretoria. According to the Shimlas Captain, his bench had a great impact, and this helped in shocking Tuks with 47-46 towards the end. This came after Tuks had been leading 43-15 in the 44th minute.

Great fighting spirit
The Shimlas' fighting spirit, and a new Varsity Cup points system in which converted tries may count up to 11 points, enabled them to wipe out this deficit.
“It was a tough match, especially after being so far behind,” Neil said.
“Coach (Hendro Scholtz) told us during half-time (when we were 15-36 behind) that we should stay calm."
“We weren't completely out of the game. We knew that if we eliminated unnecessary mistakes, we could make it.”

Impact from bench
This is the second consecutive match - the other was against Ikeys in Cape Town - where the Shimlas’ substitutes swayed the match. “The bench made a big difference,” Neil said. “We also scored an 11-point try, which helped a lot.”
The Shimlas’ fullback, Marco Mason, was named Player of the Match. He succeeded with a tricky conversion to gain victory for his team.

Injuries
The eighth man, Nardus Erasmus (knee) and flanker, Fiffy Rampeta (eye socket), sustained injuries, but should be able to play in the first home game against the Madibaz on 22 February 2016. The injured scrumhalf, Zee Mkhabela (concussion), could return for this match.
Shimlas are second on the log, with nine league points after two away matches. Maties has ten league points.

Young Guns get stuck
The University of the Free State (UFS') Young Guns got stuck 8-14 against Tuks in Pretoria on 15 February 2016.
Vishuis, the UFS's residence team, will start their onslaught in the residence league against Dagbreek in Stellenbosch on 22 February 2016.

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