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15 June 2021 | Story Leonie Bolleurs | Photo Supplied
Zurika Murray says the study of Behavioural Genetics at the UFS focuses on human behaviour, specifically neurotransmitter systems, such as serotonin that may contribute to specific behavioural patterns.
Zurika Murray says the study of Behavioural Genetics at the UFS focuses on human behaviour, specifically neurotransmitter systems, such as serotonin that may contribute to specific behavioural patterns.

Hi. I am John. I have anger issues.

Just like John, there are thousands of South Africans with anger issues, often leading to violent crimes such as the more than 21 000 murder cases and 165 000 plus assault cases reported in 2020, according to a study by the South African Police Service and Statistics South Africa.

Aggression can be a great threat to society when it leads to violence. However, it can also be an absolute necessity when it leads to perseverance and a drive towards success and survival. This is according to Zurika Murray, a lecturer in the Department of Genetics at the University of the Free State (UFS), who is doing research on behavioural genetics.

 

Behavioural genetics

She explains behavioural genetics as a study of genetic variation contributing to how an organism interacts with and within its environment. “At the UFS, we focus on human behaviour, and specifically neurotransmitter systems, such as serotonin that may contribute to specific behavioural patterns.”

When one has the right amount of serotonin in your body, it is easier to have stable moods and a sense of well-being.

She says the neurotransmitter (which plays a role in, among others, emotional regulation) acts as a mediator, relaying messages and influencing response to environmental stimuli.  “This system is very adaptable, facilitating our functioning in an ever-changing emotional environment; but when dysfunctional, it can cause quite a number of abnormalities, from anxiety and depression to dysfunctional impulse control and violence. When some individuals are exposed to adverse developmental environments such as abuse and neglect, they can develop aggression and violence.”

“One of our current projects looks specifically at male juvenile delinquency and monoamine neurotransmitter systems (such as serotonin) that may contribute to specific characteristics (such as impulsivity) of delinquency.”

According to Murray, their research is also looking at the genetic variation within specific neurotransmitter genes to see if they could find similarities among individuals with similar developmental backgrounds.  “This neurotransmitter system additionally responds relatively well to physical activity as a management strategy for aggression in some individuals. We are looking at variations in this system that might explain this,” says Murray.

 

Genetic counselling

Apart from the genetic contribution, we also know that the developmental environment plays a very important role. Many people observe anger while growing up – it was thus part of their developmental environment. For them, it is appropriate behaviour in specific situations.

To understand this contribution from the developmental environment, a background in psychology is necessary.  The undergraduate degree in Behavioural Genetics at the UFS has Genetics and Psychology as majors, and this is where the link to genetic counselling comes in.

Murray explains that genetic counselling is a field in medical sciences focusing on helping patients affected by medical conditions to understand the underlying genetics.  For individuals with a family history of genetic conditions (such as specific cancers) or pregnant mothers with foetuses affected by genetic abnormalities (such as Down syndrome), the services of a genetic counsellor are invaluable.  A genetic counsellor will help these individuals understand the cause of the disorder, how it was diagnosed, what the symptoms are, what the progression will look like, if any treatment is available, and what the possible options are (if any) for alternatives.

Genetic counsellors need a strong background in both Genetics and Psychology. To become a registered genetic counsellor, a student completes a BSc degree in Biological Sciences (Behavioural Genetics at the UFS would be ideal).  Thereafter an honours degree in either Genetics or Psychology (though Genetics is preferable).  The student can then apply at either the University of the Witwatersrand or the University of Cape Town for a master’s degree in Genetic Counselling.  This entails two years of study, followed by two years of practical internship. Only after this you will be able to register with the Health Professions Council of South Africa (HPCSA) as a genetic counsellor.

Students studying Behavioural Genetics at the UFS are off to a great start. Murray’s teaching philosophy is to always strive to deliver students who are better than she is. “I can only really do this by sharing my passion for my research. I hope to inspire my students to also always be hungrily curious, to always question, and to find the joy in knowledge and learning.”

News Archive

Einstein's gravitational waves as creative as Bach's music, says UFS physicist
2016-02-19

Description: Gravitational waves  Tags: Gravitational waves

Profile of the gravitational waves of the colliding black holes.

Prof Pieter Meintjes, Affiliated Researcher in the Department of Physics at the University of the Free State, welcomed the work done by the Laser Interferometer Gravitational-Wave Observatory (LIGO) science team.
 
For the first time, researchers from two of the American Ligo centres, in Washington and Louisiana respectively, observed gravitational waves directly, 100 years after Albert Einstein said they existed. "My study field in astrophysics involves relativistic systems. Therefore, Einstein's view of gravity is crucial to me. I consider the theory as the highest form of human creativity - just like the music of JS Bach. Over the past 100 years, the theory has been tested through various experiments and in different ways.
 
“The discovery of gravitational waves was the last hurdle to overcome in making this absolutely unfaltering. I am therefore thrilled by the discovery. It is absolutely astounding to imagine that the equations used to make the predictions about the gravitational-wave emissions when two gravitational whirlpools collide - as discovered on 14 September 2015 by LIGO - are basically Einstein's original equations that were published way back in 1916 - in other words, 100 years ago.
 
“The LIGO detectors have been operational since the early 1990s, but they had to undergo several stages of upgrades before being sensitive enough to make detections. LIGO is currently in its final stage, and is expected to function at optimal sensitivity only within a year or two. To be able to conduct the measurements at this stage is therefore a fantastic achievement, since much more funding will certainly be deposited in the project,” Prof Meintjes says.

Description: Prof Pieter Meintjes Tags: Prof Pieter Meintjes

Prof Pieter Meintjes
Photo: Charl Devenish

The search for gravitational waves by means of the Square Kilometre Array (SKA) is one of the focus points in research by both Prof Meintjes and PhD student, Jacques Maritz. This involves the study of radio signals from pulsars that might show signs of effects by gravitational waves. They are looking for signs of gravitational waves. The gravitational waves discovered and studied in this manner would naturally vary much more slowly than the signal discovered from the two colliding gravitational waves.
 
The discovery will definitely provide renewed impetus to the Square Kilometre Array (SKA) Project to use the dispersion of pulsar signals, and to search for the impact of gravitational waves on signals as they travel through the universe. According to Prof Meintjes, the SKA will definitely contribute fundamentally to the Frontier research, which will provide a good deal of publicity for the UFS and South Africa, if significant contributions are made by local researchers in this field.

Video clip explaining gravitational waves

 

  • The Department of Physics will present a general, non-technical talk concerning the recent detection of gravitational waves by the 2 Laser Interferometer Gravitational Wave Observatories (LIGO):

Wednesday 24 February 2016
11:00-12:00
New lecture auditorium, Department of Physics

 

 

 

 

 

 

 

 

 

 

 

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