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15 June 2021 | Story Leonie Bolleurs | Photo Supplied
Zurika Murray says the study of Behavioural Genetics at the UFS focuses on human behaviour, specifically neurotransmitter systems, such as serotonin that may contribute to specific behavioural patterns.
Zurika Murray says the study of Behavioural Genetics at the UFS focuses on human behaviour, specifically neurotransmitter systems, such as serotonin that may contribute to specific behavioural patterns.

Hi. I am John. I have anger issues.

Just like John, there are thousands of South Africans with anger issues, often leading to violent crimes such as the more than 21 000 murder cases and 165 000 plus assault cases reported in 2020, according to a study by the South African Police Service and Statistics South Africa.

Aggression can be a great threat to society when it leads to violence. However, it can also be an absolute necessity when it leads to perseverance and a drive towards success and survival. This is according to Zurika Murray, a lecturer in the Department of Genetics at the University of the Free State (UFS), who is doing research on behavioural genetics.

 

Behavioural genetics

She explains behavioural genetics as a study of genetic variation contributing to how an organism interacts with and within its environment. “At the UFS, we focus on human behaviour, and specifically neurotransmitter systems, such as serotonin that may contribute to specific behavioural patterns.”

When one has the right amount of serotonin in your body, it is easier to have stable moods and a sense of well-being.

She says the neurotransmitter (which plays a role in, among others, emotional regulation) acts as a mediator, relaying messages and influencing response to environmental stimuli.  “This system is very adaptable, facilitating our functioning in an ever-changing emotional environment; but when dysfunctional, it can cause quite a number of abnormalities, from anxiety and depression to dysfunctional impulse control and violence. When some individuals are exposed to adverse developmental environments such as abuse and neglect, they can develop aggression and violence.”

“One of our current projects looks specifically at male juvenile delinquency and monoamine neurotransmitter systems (such as serotonin) that may contribute to specific characteristics (such as impulsivity) of delinquency.”

According to Murray, their research is also looking at the genetic variation within specific neurotransmitter genes to see if they could find similarities among individuals with similar developmental backgrounds.  “This neurotransmitter system additionally responds relatively well to physical activity as a management strategy for aggression in some individuals. We are looking at variations in this system that might explain this,” says Murray.

 

Genetic counselling

Apart from the genetic contribution, we also know that the developmental environment plays a very important role. Many people observe anger while growing up – it was thus part of their developmental environment. For them, it is appropriate behaviour in specific situations.

To understand this contribution from the developmental environment, a background in psychology is necessary.  The undergraduate degree in Behavioural Genetics at the UFS has Genetics and Psychology as majors, and this is where the link to genetic counselling comes in.

Murray explains that genetic counselling is a field in medical sciences focusing on helping patients affected by medical conditions to understand the underlying genetics.  For individuals with a family history of genetic conditions (such as specific cancers) or pregnant mothers with foetuses affected by genetic abnormalities (such as Down syndrome), the services of a genetic counsellor are invaluable.  A genetic counsellor will help these individuals understand the cause of the disorder, how it was diagnosed, what the symptoms are, what the progression will look like, if any treatment is available, and what the possible options are (if any) for alternatives.

Genetic counsellors need a strong background in both Genetics and Psychology. To become a registered genetic counsellor, a student completes a BSc degree in Biological Sciences (Behavioural Genetics at the UFS would be ideal).  Thereafter an honours degree in either Genetics or Psychology (though Genetics is preferable).  The student can then apply at either the University of the Witwatersrand or the University of Cape Town for a master’s degree in Genetic Counselling.  This entails two years of study, followed by two years of practical internship. Only after this you will be able to register with the Health Professions Council of South Africa (HPCSA) as a genetic counsellor.

Students studying Behavioural Genetics at the UFS are off to a great start. Murray’s teaching philosophy is to always strive to deliver students who are better than she is. “I can only really do this by sharing my passion for my research. I hope to inspire my students to also always be hungrily curious, to always question, and to find the joy in knowledge and learning.”

News Archive

nGAP lecturers welcomed by the UFS academic community
2016-06-30

Description: nGAP lecturers group photo Tags: nGAP lecturers group photo

University of the Free State’s newly-appointed nGAP
lecturers. From the left, Neo Mathinya,
Phumudzo Tharaga, and Kelebogile Boleu.

The University of the Free State (UFS) was allocated six positions as part of the Department of Higher Education and Training (DHET) New Generation of Academics Programme (nGAP). Four candidates have filled positions in the Faculty of Health Sciences, Faculty of the Humanities and the Faculty of Natural and Agricultural Sciences – with two positions still vacant.

According to Minister of Higher Education and Training, Dr Blade Nzimande, nGAP is part of the Staffing South Africa's Universities Framework, which focuses on the expansion of the size and compilation of academic staff at South African universities, especially with regard to transformation. The focus of the programme is the appointment of black and coloured candidates as well as women.

The Department of Soil, Crop, and Climate Sciences in the Faculty of Natural and Agricultural Sciences welcomed two nGAP lecturers, Phumudzo Tharaga and Neo Mathinya. The Faculty was allocated four positions. Two positions are filled, while two positions in the Department of Animal and Wildlife Sciences are almost ready to be filled with exceptional candidates.

Agrometeorologist with his feet on the ground
Phumudzo Tharaga holds an MSc from the UFS, and is currently pursuing a PhD. Tharaga’s research focuses on quantifying the water use efficiency of sweet cherry orchards under different climate conditions in the Eastern Free State. Tharaga will offer his students a wealth of practical experience, which he began accumulating while working at ABSA as an agro-meteorologist, before moving on to become a senior scientist at the South African Weather Service. In 2015, Tharaga became a research technologist at the Council for Scientific and Industrial Research (CSIR) and then returned to the UFS as an nGAP candidate at the beginning of 2016.  

Description: Beynon Abrahams, nGap lecturer  Tags: Beynon Abrahams, nGap lecturer

Beynon Abrahams, nGap lecturer
at the Faculty of Heath Sciences
Department of Basic medicine

Motivated scholar turned academic
Neo Mathinya, who hails from Taung in the North West, has made the UFS her home. She received both her undergraduate and honours degrees from the university. Apart from joining the department as a lecturer under the nGAP initiative, she is currently studying for her MSc in Soil Physics. She will continue with this research when she comes to her PhD. Mathinya’s research focuses on soil salinity - the process of increasing salt content - which affects the ability of plants to take up water, a process, known as osmotic stress. She will investigate the effects of irrigation water salinity on the grain yield and quality of malt barley.

Researcher with a passion for crime prevention
Kelebogile Boleu joined the Department of Criminology in the Faculty of Humanities, with a fresh take on diversion and crime prevention. Boleu holds a BA Criminology (Hons) and is now pursuing her Master’s degree. She worked for NICRO a non-profit organisation specialising in social crime prevention and offender reintegration, with programmes that prevent young and first-time offenders from re-offending, thus reducing crime. Boleu said that her practical experience makes her lectures to third-year criminology students exciting. Boleu’s research focuses on analysing the value of pre-sentencing reports in assisting adjudicators to make well-balanced judgments in cases.   

Research with a winning plan for fight against breast cancer
Beynon Abrahams joined the Department of Basic Medical Sciences in the Faculty of Health Sciences. Abrahams holds a BSc, BSc (Hons), and MSc in Medical Biosciences from the University of the Western Cape. Abrahams’ Master’s research focused on breast cancer, research on which he is building in his PhD. This doctoral research involves the exploration of P-glycoprotein, a protein expressed on cancer cell and responsible for multi-drug resistance in cancer treatment. The aim of this research is to develop a therapeutic drug treatment strategy that will improve breast cancer patient survival outcomes. Abrahams’s greater vision is to look at conventional cancer therapeutic regimens, to find ways in which they can be improved.

The nGAP initiative offers these young lecturers an opportunity for growth and development as academics, while providing them with opportunities they would have not have been exposed to otherwise.

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