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15 June 2021 | Story Leonie Bolleurs | Photo Supplied
Zurika Murray says the study of Behavioural Genetics at the UFS focuses on human behaviour, specifically neurotransmitter systems, such as serotonin that may contribute to specific behavioural patterns.
Zurika Murray says the study of Behavioural Genetics at the UFS focuses on human behaviour, specifically neurotransmitter systems, such as serotonin that may contribute to specific behavioural patterns.

Hi. I am John. I have anger issues.

Just like John, there are thousands of South Africans with anger issues, often leading to violent crimes such as the more than 21 000 murder cases and 165 000 plus assault cases reported in 2020, according to a study by the South African Police Service and Statistics South Africa.

Aggression can be a great threat to society when it leads to violence. However, it can also be an absolute necessity when it leads to perseverance and a drive towards success and survival. This is according to Zurika Murray, a lecturer in the Department of Genetics at the University of the Free State (UFS), who is doing research on behavioural genetics.

 

Behavioural genetics

She explains behavioural genetics as a study of genetic variation contributing to how an organism interacts with and within its environment. “At the UFS, we focus on human behaviour, and specifically neurotransmitter systems, such as serotonin that may contribute to specific behavioural patterns.”

When one has the right amount of serotonin in your body, it is easier to have stable moods and a sense of well-being.

She says the neurotransmitter (which plays a role in, among others, emotional regulation) acts as a mediator, relaying messages and influencing response to environmental stimuli.  “This system is very adaptable, facilitating our functioning in an ever-changing emotional environment; but when dysfunctional, it can cause quite a number of abnormalities, from anxiety and depression to dysfunctional impulse control and violence. When some individuals are exposed to adverse developmental environments such as abuse and neglect, they can develop aggression and violence.”

“One of our current projects looks specifically at male juvenile delinquency and monoamine neurotransmitter systems (such as serotonin) that may contribute to specific characteristics (such as impulsivity) of delinquency.”

According to Murray, their research is also looking at the genetic variation within specific neurotransmitter genes to see if they could find similarities among individuals with similar developmental backgrounds.  “This neurotransmitter system additionally responds relatively well to physical activity as a management strategy for aggression in some individuals. We are looking at variations in this system that might explain this,” says Murray.

 

Genetic counselling

Apart from the genetic contribution, we also know that the developmental environment plays a very important role. Many people observe anger while growing up – it was thus part of their developmental environment. For them, it is appropriate behaviour in specific situations.

To understand this contribution from the developmental environment, a background in psychology is necessary.  The undergraduate degree in Behavioural Genetics at the UFS has Genetics and Psychology as majors, and this is where the link to genetic counselling comes in.

Murray explains that genetic counselling is a field in medical sciences focusing on helping patients affected by medical conditions to understand the underlying genetics.  For individuals with a family history of genetic conditions (such as specific cancers) or pregnant mothers with foetuses affected by genetic abnormalities (such as Down syndrome), the services of a genetic counsellor are invaluable.  A genetic counsellor will help these individuals understand the cause of the disorder, how it was diagnosed, what the symptoms are, what the progression will look like, if any treatment is available, and what the possible options are (if any) for alternatives.

Genetic counsellors need a strong background in both Genetics and Psychology. To become a registered genetic counsellor, a student completes a BSc degree in Biological Sciences (Behavioural Genetics at the UFS would be ideal).  Thereafter an honours degree in either Genetics or Psychology (though Genetics is preferable).  The student can then apply at either the University of the Witwatersrand or the University of Cape Town for a master’s degree in Genetic Counselling.  This entails two years of study, followed by two years of practical internship. Only after this you will be able to register with the Health Professions Council of South Africa (HPCSA) as a genetic counsellor.

Students studying Behavioural Genetics at the UFS are off to a great start. Murray’s teaching philosophy is to always strive to deliver students who are better than she is. “I can only really do this by sharing my passion for my research. I hope to inspire my students to also always be hungrily curious, to always question, and to find the joy in knowledge and learning.”

News Archive

SADoCoL receives partial reinstatement of blood sample testing by the World Anti-Doping Agency
2016-08-22

Last week, the World Anti-Doping Agency (WADA) announced the lifting of the suspension of blood sample analysis by the South African Doping Control Laboratory (SADoCoL) at the University of the Free State (UFS). Although the suspension of urine sample analysis is still under review, the UFS is appreciative of the new outcome. The initial temporary suspension of SADoCoL, announced on 3 May 2016, included the suspension of all doping-control procedures which applied to both urine and blood samples.

The main reason for the suspension involved analytical techniques relevant to urine analysis; however, the testing of blood samples was also included in the suspension. At the time of the suspension, no adverse findings were reported for the laboratory in relation to blood-sample testing for Athlete Blood Passport (ABP) assessment. 

According to the agreement with WADA, the suspension period would be utilised to implement and test new systems in order to achieve the standard presently required by WADA, as well as to perform development and improvements. SADoCoL is a specialised service laboratory of the UFS and has been in existence for more than thirty years.

Upon SADoCoL’s request to lift the suspension of only the ABP analysis, WADA agreed to allow the laboratory to apply for reaccreditation.  SADoCoL immediately applied for reaccreditation of ABP analysis on blood, so that the laboratory would be allowed to at least offer this service to the Anti-Doping community in Africa.

For this purpose, inspections were performed by the South African National Accreditation System (SANAS) and by WADA, during which all aspects of blood analysis by the laboratory were thoroughly assessed and tested.  The successful outcome of these inspections resulted in the reaccreditation of SADoCoL by WADA in order to perform ABP analysis as required by the WADA International Standard for Laboratories, with effect from 4 August 2016. 

This outcome allows the laboratory to once again perform this very essential analytical procedure.  The South African Institute for Drug-Free Sport (SAIDS) and other regular users can now continue to send blood samples to SADoCoL for ABP analysis, instead of making use of alternative laboratories.

 

Released by: Lacea Loader (Director: Communication and Brand Management)
Tel: +27 51 401 3422/2707 or +27 83 645 2454
Email: news@ufs.ac.za  | loaderl@ufs.ac.za
Fax: +27 51 444 6393

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