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15 June 2021 | Story Leonie Bolleurs | Photo Supplied
Zurika Murray says the study of Behavioural Genetics at the UFS focuses on human behaviour, specifically neurotransmitter systems, such as serotonin that may contribute to specific behavioural patterns.
Zurika Murray says the study of Behavioural Genetics at the UFS focuses on human behaviour, specifically neurotransmitter systems, such as serotonin that may contribute to specific behavioural patterns.

Hi. I am John. I have anger issues.

Just like John, there are thousands of South Africans with anger issues, often leading to violent crimes such as the more than 21 000 murder cases and 165 000 plus assault cases reported in 2020, according to a study by the South African Police Service and Statistics South Africa.

Aggression can be a great threat to society when it leads to violence. However, it can also be an absolute necessity when it leads to perseverance and a drive towards success and survival. This is according to Zurika Murray, a lecturer in the Department of Genetics at the University of the Free State (UFS), who is doing research on behavioural genetics.

 

Behavioural genetics

She explains behavioural genetics as a study of genetic variation contributing to how an organism interacts with and within its environment. “At the UFS, we focus on human behaviour, and specifically neurotransmitter systems, such as serotonin that may contribute to specific behavioural patterns.”

When one has the right amount of serotonin in your body, it is easier to have stable moods and a sense of well-being.

She says the neurotransmitter (which plays a role in, among others, emotional regulation) acts as a mediator, relaying messages and influencing response to environmental stimuli.  “This system is very adaptable, facilitating our functioning in an ever-changing emotional environment; but when dysfunctional, it can cause quite a number of abnormalities, from anxiety and depression to dysfunctional impulse control and violence. When some individuals are exposed to adverse developmental environments such as abuse and neglect, they can develop aggression and violence.”

“One of our current projects looks specifically at male juvenile delinquency and monoamine neurotransmitter systems (such as serotonin) that may contribute to specific characteristics (such as impulsivity) of delinquency.”

According to Murray, their research is also looking at the genetic variation within specific neurotransmitter genes to see if they could find similarities among individuals with similar developmental backgrounds.  “This neurotransmitter system additionally responds relatively well to physical activity as a management strategy for aggression in some individuals. We are looking at variations in this system that might explain this,” says Murray.

 

Genetic counselling

Apart from the genetic contribution, we also know that the developmental environment plays a very important role. Many people observe anger while growing up – it was thus part of their developmental environment. For them, it is appropriate behaviour in specific situations.

To understand this contribution from the developmental environment, a background in psychology is necessary.  The undergraduate degree in Behavioural Genetics at the UFS has Genetics and Psychology as majors, and this is where the link to genetic counselling comes in.

Murray explains that genetic counselling is a field in medical sciences focusing on helping patients affected by medical conditions to understand the underlying genetics.  For individuals with a family history of genetic conditions (such as specific cancers) or pregnant mothers with foetuses affected by genetic abnormalities (such as Down syndrome), the services of a genetic counsellor are invaluable.  A genetic counsellor will help these individuals understand the cause of the disorder, how it was diagnosed, what the symptoms are, what the progression will look like, if any treatment is available, and what the possible options are (if any) for alternatives.

Genetic counsellors need a strong background in both Genetics and Psychology. To become a registered genetic counsellor, a student completes a BSc degree in Biological Sciences (Behavioural Genetics at the UFS would be ideal).  Thereafter an honours degree in either Genetics or Psychology (though Genetics is preferable).  The student can then apply at either the University of the Witwatersrand or the University of Cape Town for a master’s degree in Genetic Counselling.  This entails two years of study, followed by two years of practical internship. Only after this you will be able to register with the Health Professions Council of South Africa (HPCSA) as a genetic counsellor.

Students studying Behavioural Genetics at the UFS are off to a great start. Murray’s teaching philosophy is to always strive to deliver students who are better than she is. “I can only really do this by sharing my passion for my research. I hope to inspire my students to also always be hungrily curious, to always question, and to find the joy in knowledge and learning.”

News Archive

Maize breeder rewarded for his research to enhance food security in Africa
2016-08-26

Description: Maize breeder rewarded  Tags: Maize breeder rewarded

Prof Maryke Labuschagne from the UFS Department
of Plant Sciences, Berhanu Tadesse Ertiro, a
postgraduate student in Plant breeding at the UFS,
and Dr Peg Redinbaugh of the US Department of
Agriculture in Wooster, Ohio.
Photo: Supplied

Ethiopia is one of the African countries, deeply affected by food insecurity. Berhanu Tadesse Ertiro, a citizen from Ethiopia started his career - after graduating with his undergraduate degree in 2003 - as a junior maize breeder. Today he is pursuing his doctorate degree in Plant Breeding at the University of the Free State (UFS).

His research had made some great strides in contributing to food security in Africa. He recently received a fellowship from the prestigious Norman E. Borlaug Leadership Enhancement in Agriculture Program (Borlaug LEAP).

This fellowship is only awarded to students whose research has relevance to the national development of the student’s home country or region. The aim of these fellowships are to enhance the quality of thesis research of graduate students from developing countries who show strong promise as leaders in the field of agriculture and related disciplines.

Low soil fertility a major maize production constraint
Berhanu is also a visiting student at the International Maize and Wheat Improvement Center (CIMMYT) in Kenya, where he is running field experiments for his PhD thesis dissertation. His research focuses on Nitrogen Use Efficiency (NUE) and Maize Lethal Necrosis (MLN) disease tolerance. Low soil fertility and MLN are among the major maize production constraints in eastern and southern Africa, where maize is staple food.

Such hybrids have the potential to contribute greatly
towards food security among farmers and their
families through increased productivity.

The use of new tools could increase breeding efficiency and reduce the time needed for the release of new stress tolerant hybrids. Such hybrids have the potential to contribute greatly towards food security among farmers and their families through increased productivity. Berhanu is looking at the feasibility of genome wide selection for improvement of NUE in tropical maize.

Fellowship includes mentorship and supervision across borders
The programme supports engaging a mentor at a United States university and Consortium of International Agricultural Research Centers (CGIAR). During his fellowship, he will be supervised and mentored by Prof Maryke Labuschagne of the UFS, Prof Rex Bernando, a professor of Corn Breeding and Genetics at the University of Minnesota and Dr Biswanath Das of CIMMYT, Kenya.

As a LEAP fellow, Berhanu was invited to attend the 30th Annual World Food Prize events to take place in October 2016, in Des Moines, Iowa. The week will include his attendance at the Board for International Food and Agricultural Development meeting, participation at side-events at the Borlaug Dialogue International Symposium and the World Food Prize.

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