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15 June 2021 | Story Leonie Bolleurs | Photo Supplied
Zurika Murray says the study of Behavioural Genetics at the UFS focuses on human behaviour, specifically neurotransmitter systems, such as serotonin that may contribute to specific behavioural patterns.
Zurika Murray says the study of Behavioural Genetics at the UFS focuses on human behaviour, specifically neurotransmitter systems, such as serotonin that may contribute to specific behavioural patterns.

Hi. I am John. I have anger issues.

Just like John, there are thousands of South Africans with anger issues, often leading to violent crimes such as the more than 21 000 murder cases and 165 000 plus assault cases reported in 2020, according to a study by the South African Police Service and Statistics South Africa.

Aggression can be a great threat to society when it leads to violence. However, it can also be an absolute necessity when it leads to perseverance and a drive towards success and survival. This is according to Zurika Murray, a lecturer in the Department of Genetics at the University of the Free State (UFS), who is doing research on behavioural genetics.

 

Behavioural genetics

She explains behavioural genetics as a study of genetic variation contributing to how an organism interacts with and within its environment. “At the UFS, we focus on human behaviour, and specifically neurotransmitter systems, such as serotonin that may contribute to specific behavioural patterns.”

When one has the right amount of serotonin in your body, it is easier to have stable moods and a sense of well-being.

She says the neurotransmitter (which plays a role in, among others, emotional regulation) acts as a mediator, relaying messages and influencing response to environmental stimuli.  “This system is very adaptable, facilitating our functioning in an ever-changing emotional environment; but when dysfunctional, it can cause quite a number of abnormalities, from anxiety and depression to dysfunctional impulse control and violence. When some individuals are exposed to adverse developmental environments such as abuse and neglect, they can develop aggression and violence.”

“One of our current projects looks specifically at male juvenile delinquency and monoamine neurotransmitter systems (such as serotonin) that may contribute to specific characteristics (such as impulsivity) of delinquency.”

According to Murray, their research is also looking at the genetic variation within specific neurotransmitter genes to see if they could find similarities among individuals with similar developmental backgrounds.  “This neurotransmitter system additionally responds relatively well to physical activity as a management strategy for aggression in some individuals. We are looking at variations in this system that might explain this,” says Murray.

 

Genetic counselling

Apart from the genetic contribution, we also know that the developmental environment plays a very important role. Many people observe anger while growing up – it was thus part of their developmental environment. For them, it is appropriate behaviour in specific situations.

To understand this contribution from the developmental environment, a background in psychology is necessary.  The undergraduate degree in Behavioural Genetics at the UFS has Genetics and Psychology as majors, and this is where the link to genetic counselling comes in.

Murray explains that genetic counselling is a field in medical sciences focusing on helping patients affected by medical conditions to understand the underlying genetics.  For individuals with a family history of genetic conditions (such as specific cancers) or pregnant mothers with foetuses affected by genetic abnormalities (such as Down syndrome), the services of a genetic counsellor are invaluable.  A genetic counsellor will help these individuals understand the cause of the disorder, how it was diagnosed, what the symptoms are, what the progression will look like, if any treatment is available, and what the possible options are (if any) for alternatives.

Genetic counsellors need a strong background in both Genetics and Psychology. To become a registered genetic counsellor, a student completes a BSc degree in Biological Sciences (Behavioural Genetics at the UFS would be ideal).  Thereafter an honours degree in either Genetics or Psychology (though Genetics is preferable).  The student can then apply at either the University of the Witwatersrand or the University of Cape Town for a master’s degree in Genetic Counselling.  This entails two years of study, followed by two years of practical internship. Only after this you will be able to register with the Health Professions Council of South Africa (HPCSA) as a genetic counsellor.

Students studying Behavioural Genetics at the UFS are off to a great start. Murray’s teaching philosophy is to always strive to deliver students who are better than she is. “I can only really do this by sharing my passion for my research. I hope to inspire my students to also always be hungrily curious, to always question, and to find the joy in knowledge and learning.”

News Archive

Researcher wins prize for her work to reduce environmental pollution
2016-12-26

Description: Josepha Zielke Tags: Josepha Zielke 

Prof Danie Vermeulen, Dean of the Faculty of Natural
and Agricultural Sciences, and Josepha Zielke, a
PhD student at the Institute for Groundwater studies at the
University of the Free State.
Photo: Leonie Bolleurs

Josepha Zielke, a PhD student at the Institute for Groundwater Studies at the University of the Free State (UFS), received the prize for the best student presentation at the International Mine Water Association (IMWA) symposium in Leipzig, Germany, this year. Her paper was titled Fine Ash Leaching in Tailings Dams – An Impact on the Underlying Aquifers?
 
Zielke said: “It is an honour to receive this prize as a student. IMWA is a big association which allows you to establish a network with other scientists, to exchange opinions and ideas and to gain new inspiration for your own work. It was exciting and informative to hear about the research conducted around the world and to meet the researchers themselves.”
 
Born in Germany, Zielke always wanted to study overseas. During an exchange year in Grade 11, she visited South Africa. When she had to make a decision about in which country to complete her studies, South Africa was first choice as she was familiar with the people and the country.
 
Zielke joins leading institute on groundwater research in the country
She completed her BSc Hons in Geology at the Nelson Mandela Metropolitan University. After working for a year in exploration, she decided to focus her studies on water-related problems which  has been a growing issue, not only in South Africa, but in many places around the world. Zielke heard that the UFS Institute for Groundwater Studies was the leading institute on groundwater research in the country, and decided to join the university.
 
After completing her MSc research, An analysis of the geochemical weathering profile within a fine ash tailings dam, Mpumalanga, South Africa, Zielke started the research for her PhD project on groundwater pollution along a fault system in Mpumalanga.
 
Research adding value to the environment by reducing pollution
She explains the focus of her research: “Several production plants and mine waste facilities are located on or near these geological structures which could be a possible cause of ground and surface water pollution. With the aid of geophysical ground surveys (using electromagnetics and electrical resistivity tomography), aquifer and tracer tests, we are trying to determine where the pollution is coming from, how far it has been distributed and to model the potential risks.
 
“This research will add value to the environment by preventing or at least reducing pollution leaking into the environment. Industrial sites always have a negative footprint on the environment but at least we try and contain it by finding the cause of ground and surface water pollution. Thereafter we try and solve the pollution problem or at least mitigate the damage to prevent the spreading of ground and surface water pollution in the area.”

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