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15 June 2021 | Story Leonie Bolleurs | Photo Supplied
Zurika Murray says the study of Behavioural Genetics at the UFS focuses on human behaviour, specifically neurotransmitter systems, such as serotonin that may contribute to specific behavioural patterns.
Zurika Murray says the study of Behavioural Genetics at the UFS focuses on human behaviour, specifically neurotransmitter systems, such as serotonin that may contribute to specific behavioural patterns.

Hi. I am John. I have anger issues.

Just like John, there are thousands of South Africans with anger issues, often leading to violent crimes such as the more than 21 000 murder cases and 165 000 plus assault cases reported in 2020, according to a study by the South African Police Service and Statistics South Africa.

Aggression can be a great threat to society when it leads to violence. However, it can also be an absolute necessity when it leads to perseverance and a drive towards success and survival. This is according to Zurika Murray, a lecturer in the Department of Genetics at the University of the Free State (UFS), who is doing research on behavioural genetics.

 

Behavioural genetics

She explains behavioural genetics as a study of genetic variation contributing to how an organism interacts with and within its environment. “At the UFS, we focus on human behaviour, and specifically neurotransmitter systems, such as serotonin that may contribute to specific behavioural patterns.”

When one has the right amount of serotonin in your body, it is easier to have stable moods and a sense of well-being.

She says the neurotransmitter (which plays a role in, among others, emotional regulation) acts as a mediator, relaying messages and influencing response to environmental stimuli.  “This system is very adaptable, facilitating our functioning in an ever-changing emotional environment; but when dysfunctional, it can cause quite a number of abnormalities, from anxiety and depression to dysfunctional impulse control and violence. When some individuals are exposed to adverse developmental environments such as abuse and neglect, they can develop aggression and violence.”

“One of our current projects looks specifically at male juvenile delinquency and monoamine neurotransmitter systems (such as serotonin) that may contribute to specific characteristics (such as impulsivity) of delinquency.”

According to Murray, their research is also looking at the genetic variation within specific neurotransmitter genes to see if they could find similarities among individuals with similar developmental backgrounds.  “This neurotransmitter system additionally responds relatively well to physical activity as a management strategy for aggression in some individuals. We are looking at variations in this system that might explain this,” says Murray.

 

Genetic counselling

Apart from the genetic contribution, we also know that the developmental environment plays a very important role. Many people observe anger while growing up – it was thus part of their developmental environment. For them, it is appropriate behaviour in specific situations.

To understand this contribution from the developmental environment, a background in psychology is necessary.  The undergraduate degree in Behavioural Genetics at the UFS has Genetics and Psychology as majors, and this is where the link to genetic counselling comes in.

Murray explains that genetic counselling is a field in medical sciences focusing on helping patients affected by medical conditions to understand the underlying genetics.  For individuals with a family history of genetic conditions (such as specific cancers) or pregnant mothers with foetuses affected by genetic abnormalities (such as Down syndrome), the services of a genetic counsellor are invaluable.  A genetic counsellor will help these individuals understand the cause of the disorder, how it was diagnosed, what the symptoms are, what the progression will look like, if any treatment is available, and what the possible options are (if any) for alternatives.

Genetic counsellors need a strong background in both Genetics and Psychology. To become a registered genetic counsellor, a student completes a BSc degree in Biological Sciences (Behavioural Genetics at the UFS would be ideal).  Thereafter an honours degree in either Genetics or Psychology (though Genetics is preferable).  The student can then apply at either the University of the Witwatersrand or the University of Cape Town for a master’s degree in Genetic Counselling.  This entails two years of study, followed by two years of practical internship. Only after this you will be able to register with the Health Professions Council of South Africa (HPCSA) as a genetic counsellor.

Students studying Behavioural Genetics at the UFS are off to a great start. Murray’s teaching philosophy is to always strive to deliver students who are better than she is. “I can only really do this by sharing my passion for my research. I hope to inspire my students to also always be hungrily curious, to always question, and to find the joy in knowledge and learning.”

News Archive

Investec guest speaker exhorts South Campus students to ‘give it their all’
2017-02-16

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Video clip
Photo Gallery

The South Campus of the University of the Free State (UFS) recently welcomed new first-year and returning senior students during an event in the Madiba Arena. This year marks another highlight for the campus, with the accommodation of 252 students in a brand-new residence named Legae (meaning “Home”) on the property.

Prof Daniella Coetzee, Campus Principal, reminded the gathered students, “You are a fully-fledged Kovsie, and this is the first day of the rest of your life. You are now going to really work on your dreams.”

She went on to relate the life story of Albert Einstein, renowned physicist, making the point, “When you work, when you persist, when you take it one day at a time, you never lose sight of your dreams, and you will reach your dreams. I can promise you one thing, dear Kovsies, that if you work hard, plan hard, and you put your mind to it, it will definitely be worthwhile.”

Setlogane Manchidi, Head of Investec’s Corporate Social Investments division and guest speaker, told his colourful life story and academic journey. He described his ‘a-ha moment’ in high school, “when the penny dropped and everything started making sense” on a visit to his mother’s employer in Johannesburg, after going to the cinema to watch a movie: “This is the life I want to live.”

Description: 'South Campus Opening Tags: South Campus, Opening
Andrew Tlou, Investec Social Investment; Carol Bunn,
UFS Institutional Advancement; Setlogane Manchidi,
Head of Investec’s Corporate Social Investments division;
Tshegofatso Setilo, UAP Programmes Manager; and
Francois Marais, Director: Access Programmes,
at the South Campus opening and orientation day.
Photo: Eugene Seegers


This led to a new resolve in his scholastic efforts at the rural school back home in Ga-Phahla, Limpopo, and he started studying over weekends and by candlelight at night. Mr Manchidi shared this lesson with the students, “At that point, I lost my so-called ‘friends.’ I learnt this: Peer pressure is real. If you want to deal with peer pressure, surround yourself with the right peers! Surround yourself with people who have your best interests at heart. Surround yourself with people who will not turn you back from your path.” He later succeeded in obtaining a bursary to study at the University of Cape Town (UCT).

Mr Manchidi concluded by exhorting students to aspire to greatness, “Every time you settle for what is expected, you rob yourself of the opportunity to prove yourself out of the ordinary. Choose to exceed expectations. Give it your all!”

 

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