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15 June 2021 | Story Leonie Bolleurs | Photo Supplied
Zurika Murray says the study of Behavioural Genetics at the UFS focuses on human behaviour, specifically neurotransmitter systems, such as serotonin that may contribute to specific behavioural patterns.
Zurika Murray says the study of Behavioural Genetics at the UFS focuses on human behaviour, specifically neurotransmitter systems, such as serotonin that may contribute to specific behavioural patterns.

Hi. I am John. I have anger issues.

Just like John, there are thousands of South Africans with anger issues, often leading to violent crimes such as the more than 21 000 murder cases and 165 000 plus assault cases reported in 2020, according to a study by the South African Police Service and Statistics South Africa.

Aggression can be a great threat to society when it leads to violence. However, it can also be an absolute necessity when it leads to perseverance and a drive towards success and survival. This is according to Zurika Murray, a lecturer in the Department of Genetics at the University of the Free State (UFS), who is doing research on behavioural genetics.

 

Behavioural genetics

She explains behavioural genetics as a study of genetic variation contributing to how an organism interacts with and within its environment. “At the UFS, we focus on human behaviour, and specifically neurotransmitter systems, such as serotonin that may contribute to specific behavioural patterns.”

When one has the right amount of serotonin in your body, it is easier to have stable moods and a sense of well-being.

She says the neurotransmitter (which plays a role in, among others, emotional regulation) acts as a mediator, relaying messages and influencing response to environmental stimuli.  “This system is very adaptable, facilitating our functioning in an ever-changing emotional environment; but when dysfunctional, it can cause quite a number of abnormalities, from anxiety and depression to dysfunctional impulse control and violence. When some individuals are exposed to adverse developmental environments such as abuse and neglect, they can develop aggression and violence.”

“One of our current projects looks specifically at male juvenile delinquency and monoamine neurotransmitter systems (such as serotonin) that may contribute to specific characteristics (such as impulsivity) of delinquency.”

According to Murray, their research is also looking at the genetic variation within specific neurotransmitter genes to see if they could find similarities among individuals with similar developmental backgrounds.  “This neurotransmitter system additionally responds relatively well to physical activity as a management strategy for aggression in some individuals. We are looking at variations in this system that might explain this,” says Murray.

 

Genetic counselling

Apart from the genetic contribution, we also know that the developmental environment plays a very important role. Many people observe anger while growing up – it was thus part of their developmental environment. For them, it is appropriate behaviour in specific situations.

To understand this contribution from the developmental environment, a background in psychology is necessary.  The undergraduate degree in Behavioural Genetics at the UFS has Genetics and Psychology as majors, and this is where the link to genetic counselling comes in.

Murray explains that genetic counselling is a field in medical sciences focusing on helping patients affected by medical conditions to understand the underlying genetics.  For individuals with a family history of genetic conditions (such as specific cancers) or pregnant mothers with foetuses affected by genetic abnormalities (such as Down syndrome), the services of a genetic counsellor are invaluable.  A genetic counsellor will help these individuals understand the cause of the disorder, how it was diagnosed, what the symptoms are, what the progression will look like, if any treatment is available, and what the possible options are (if any) for alternatives.

Genetic counsellors need a strong background in both Genetics and Psychology. To become a registered genetic counsellor, a student completes a BSc degree in Biological Sciences (Behavioural Genetics at the UFS would be ideal).  Thereafter an honours degree in either Genetics or Psychology (though Genetics is preferable).  The student can then apply at either the University of the Witwatersrand or the University of Cape Town for a master’s degree in Genetic Counselling.  This entails two years of study, followed by two years of practical internship. Only after this you will be able to register with the Health Professions Council of South Africa (HPCSA) as a genetic counsellor.

Students studying Behavioural Genetics at the UFS are off to a great start. Murray’s teaching philosophy is to always strive to deliver students who are better than she is. “I can only really do this by sharing my passion for my research. I hope to inspire my students to also always be hungrily curious, to always question, and to find the joy in knowledge and learning.”

News Archive

Famous mineralogists visit UFS Geology
2017-04-25

Description: Famous mineralogists visits UFS Geology Tags: Famous mineralogists visits UFS Geology

From the left: Prof Marian Tredoux, Associate
Professor at the UFS Department of Geology;
Prof Giorgio Garuti; from the University of Leoben,
Dr Federica Zaccarini, also from the
University of Leoben and Dr Freddie Roelofse,
Head of the Department of Geology at the UFS.
Photo: Rulanzen Martin


Years of academic friendship and collaboration is what makes Prof Giorgio Garuti and Dr Federica Zaccarini return to the University of the Free State (UFS) every so often.

The world-renowned academic duo from the University of Leoben in Austria were guest lecturers at the UFS Department of Geology. “We are here because we have known Professor Marian Tredoux and the Geology Department, for a long time. We are really happy to be here, and to be given the opportunity to present talks,” said Dr Zaccarini. The two are experts in platinum-group element mineralogy and each has given their surname to minerals namely, the Garutiite and Zaccariniite minerals.

Visit great advantage for research

They are acclaimed experts on very small minerals (smaller than a hundredth of a millimetre) with emphasis on platinum group elements in chrome-rich rocks. “Their visit is a great advantage for us. We also conduct research on these minerals and can learn from them,” said Prof Marian Tredoux, affiliated researcher at the Department of Geology.

Dr Zaccarini gave a lecture on Chromitites, and associated platinum-group elements, in ophiolites on Wednesday 5 April 2017 and Dr Garuti presented a lecture on Uralian-Alaskan complexes: a puzzling source of platinum, on Thursday 6 April 2017. During the talks they examined the association of the platinum-group minerals with chromite, rather than sulphide, and how this association can lead to the formation of unusual platinum-group element ores.

Collaboration on various academic papers

They and Prof Tredoux have collaborated on various research articles over the past four years, which have been published in various important international scientific journals. “These journals play an important role in calculating the H-scale which measures how important a researcher’s work is on an international scale,” said Prof Tredoux.

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