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30 March 2021 | Story Prof Francis Petersen | Photo Sonia Small (Kaleidoscope Studios)
Prof Francis Petersen.

Systems, processes, and policies are not exactly things that grab the headlines or are popular topics for dinner conversations. But they become vital in times of crisis. 
And if there is one thing that we have learnt from the COVID-19 pandemic, it is that no amount of time, effort or resources should be spared to get them in place before disaster strikes, says Prof Francis Petersen.

During my own education and training in the field of engineering, I was constantly reminded of the value of systems: a set of components working together as parts of a mechanism or an interconnecting network; a complex whole. In subsequent years, I also realised time and time again how system principles can be applied equally successfully in management. In any organisation, systems ensure unified and stable operation. And in times of crisis, they prevent hysteria, uncertainty, and unnecessary waste of time.

Lessons learned in reaction to the pandemic

At the University of the Free State (UFS), we quickly learned the value of acting proactively when it comes to the COVID-19 pandemic, as well as getting sustainable systems in place that operated in unity. Amid all the uncertainty and change, we found that it was vital not to re-act in a knee-jerk manner and steered away from implementing random measures that did not consider the entire institution, its history (how it grew and developed up to this point in time), and its future (the altered, post-COVID-19 landscape).

Early reaction and a sustained focus on the period after the pandemic, characterised our response action. A UFS COVID-19 Task Team was already formed at the end of February 2020, as news of the first infections trickled in from Wuhan, China.

When the first South African COVID-19 infection was reported on 5 March 2020, a Special Executive Group moved into action. It had several focus areas: Teaching and Learning, Staff, Operations, Re-integration of Staff and Students on Campus, Finance, Risk and Legal, COVID-19 Science, and Future Thinking. We immediately began the migration to remote teaching and learning, which involved the training of staff, getting the material online, briefing students, procuring laptops, and zero rating the learning portals.

In mid-March 2020, staff who were able to, were asked to work from home. Events were postponed, staff and students were trained to work in a remote setting, and a moratorium was placed on international travel – even before a national lockdown was put in place by government.

In retrospect, this timely, holistic, systematic approach proved to be invaluable.

Learning from a global system

The pandemic also reinforced the lesson that no country is an island. We should learn from others, not repeat their mistakes, and not ignore their successes.

A successful system never operates in isolation, but is affected by, and has an influence on the systems around it.

As we are entering the vaccine phase of the pandemic, it is more vital than ever to maintain a ‘systems’ approach.  Now is not the time for shortcuts, untested remedies, and vague claims of efficiency. Now is the time for systematic implementation of tried and tested processes, developed over time and underscored by good science.

Our part in the vaccine production system

At the UFS, we are privileged to play a role on two important fronts: 

The South African National Control Laboratory for Biological Products (NCLBP) located on our Bloemfontein Campus, is performing the all-important task of vaccine-lot release. As the sole provider of this service in the country and one of only twelve World Health Organisation (WHO)-contracted laboratories worldwide for vaccine quality-control testing, it forms part of a carefully crafted regulatory system, which has been established, fine-tuned, and tested over many years to serve the interests of the global community.

Vaccines are biological medicines and some of the most complex pharmaceuticals available today. It is vital that their regulation be governed by scientific and not commercial or political principles. It is a role that should under no circumstances simply be given to the ‘lowest bidder’ or the one who promises ‘speedy delivery’.

The NCLBP did not get to play this regulatory role overnight. It was already established in 1997 after an extremely stringent audit by the National Regulatory Authority (NRA) and subsequent recommendations by the WHO.

This means that all its operations – from the way documents are compiled and stored, to the maintenance of equipment and infrastructure, as well as staff competency – are performed according to strict international guidelines and are continuously and closely monitored.

It forms part of an involved system with checks and balances in place to ensure that no mistakes are made. 

Similarly, FARMOVS – a wholly owned clinical research company of the UFS, together with several medical and scientific experts at the university –  has submitted a clinical trial protocol for approval to the South African Health Products Regulatory Authority (SAHPRA) to determine the efficacy of Ivermectin for COVID-19.
FARMOVS was systematically prepared and shaped for this role, having been involved in countless pharmaceutical trials, proving its own efficacy consistently over a protracted period.
Not only is it the only onsite ISO- (International Organisation for Standardisation) and GLP- (Good Laboratory Practice) certified bioanalytical laboratory on the African continent – it has continuously proven itself to adhere to the most rigorous international requirements over the past 47 years.   

It is extremely satisfying – and reassuring – to see how institutions like these two, rooted in sound science, and having proven their consistency, efficiency, and accuracy over many years, are now stepping up to the plate and performing the all-important functions for which they were painstakingly and systematically designed. 

‘Vaccine nationalism’

This pandemic has shown that, through the interconnectedness of our world, one country or region has an impact (in this particular case a health-impact) on other countries and regions. In this context, it is up to rich countries to ensure fair and equitable access to vaccines for poorer countries, and that the WHO proposal to request pharmaceutical companies to waive their intellectual property rights in this regard, should be supported. 

‘Good science’ more important than ever

Another thing the pandemic has highlighted, is the importance of good, sound science amid all the hype, speculation, and false news that unfortunately also characterise the COVID-19 era. 

The co-incidental meteoric rise in the popularity of social media has fuelled the fire of unverified and unscientific claims that are so often just lapped up by information consumers in the public sphere. Unfortunately, since we have entered the vaccine phase, this has become increasingly rife. 

Here, the role of universities as education and research facilities is becoming more important than ever. Not only do we need to provide and communicate the ‘good science’ that everyone craves. But instead of simply advising from the side-line, we should also be playing a vital practical role, actively applying our knowledge, resources, and expertise within the broader society we serve, as has been aptly demonstrated in our important role of vaccine regulating.

Role of universities in the post-pandemic era

Without a doubt, the pandemic has highlighted the importance of online learning, the huge need that exists to be properly equipped for this and has given us a powerful shove in a direction we were already advancing to.

But it has also shown us that, in the midst of increasing digitisation, our need for social and physical interaction remains. The isolation brought about by COVID-19 has taught us that we cannot only function as a digital society. This will probably lead to higher-education institutions presenting a blended mode of learning and teaching in the future; a combination of online learning and face-to-face interactions, ensuring that students still get to experience campus life and the valuable interactions that go with it. 

The pandemic has also helped to crystalise the way in which we as ‘generators of knowledge’ should interact with society. The recent rhetoric of anti-scientific world leaders has caused communities to become distrustful of universities and science. 

We need to actively work on building trust within communities again. And we can only do this by working closely with other sectors of society, gauging real needs, and working together as parts of a bigger system in order to find real, practical solutions that can be seen by everyone to make a positive change in different spheres of society. 

Every organisation, business, government, and institution benefit from having both visionaries and pragmatists.  The visionaries help us to imagine a future we want to live in. The pragmatists work out practical, doable, and sustainable steps to get there. 

Sometimes it becomes necessary for the activists and orators to step aside and create space for the scientists and administrators to systematically get on with what needs to be done.
While we are all eager to move beyond this period in our collective history, back to a world that resembles more of the ‘old normal’ we long for, we should not make hasty, ill-considered moves and take shortcuts to get there.

We should also see this period as our opportunity to push our boundaries, embrace the ‘new normal’, and be innovative in our thinking on how to stay there. 


(Prof Francis Petersen is a registered professional engineer and has served on the executive managements of higher-education institutions, science councils, and industry organisations.)

News Archive

During 2011: Prestige Scholars Programme (PSP)
2011-12-01

The University has designed the Vice-Chancellor’s Prestige Scholars Programme (PSP) to promote and support the intellectual breadth and depth required of young scholars to pose questions and generate knowledge in their disciplines and hence to occupy the vanguards of contemporary intellectual enquiry. The programme specifically targets members of the academic staff who are near completion, or have newly completed, their doctoral studies.

The goal is to select no more than 100 of the most promising young scholars and to make substantial investments in their development towards becoming full professors. A tailored, intensive programme of support is designated that combines international placement working alongside leading scholars in the discipline of the prestige scholar, with intensive mentorship and support from within the university.

 Description: 2011 PSP_Thuthuka  Tags: 2011 PSP_Thuthuka

Elite young scholars on the Vice-Chancellor’s Prestige Scholars Programme generated R1,2 million in National Research Foundation Thuthuka and Blue Skies funding in 2011 alone. Dr Katinka de Wet in the Department of Sociology was awarded Blue Skies funding for her work on the Hybrid Identity of the HIV/Aids patient. Thuthuka Grant holders Drs Cilliers van den Berg, Olihile Sebolai, Dirk Opperman and Diaan van der Westhuizen work in the fields of German and Afrikaans trauma literature, microbiology, structural and evolutionary biology, and architecture, respectively. This broad disciplinary range typifies the depth and extraordinary range of scholarship present among junior academics at the UFS.


 Description: 2011 PSP_Liza Coetsee Tags: 2011 PSP_Liza Coetsee

Dr Liza Coetsee, a Y2-rated physicist, is the first of the Vice-Chancellor’s elite cohort of Prestige Scholars to submit for National Research Foundation rating. Dr Coetsee works on the latest of the Nanotechnology Surface Science systems housed in our Department of Physics. As Prestige Scholar, Dr Coetsee conducts research on phosphor solar cells. Her aim is to establish a new Phosphor Solar Cell field at the University of the Free State with Proff. Hendrik Swart and Koos Terblans. As a member of the Prestige Scholar Programme, Dr Coetsee will work in collaboration both with colleagues from the Nelson Mandela Metropolitan University and Prof. Eray Aydil from the University of Minnesota and Editor-in-Chief of the Journal of Vacuum Science & Technology.


 Description: 2011 PSP_Olihile Sebolai Tags: 2011 PSP_Olihile Sebolai

Dr Olihile Sebolai is one of the 2 Vice-Chancellor’s elite Prestige Scholars and a microbiologist. In 2011, Dr Sebolai was awarded a Thuthuka Grant for his research on the yeast pathogen Cryptococcus neoformans, the cause of life-threatening Aids-defining illnesses such as meningitis. Dr Sebolai considers how cryptococcal lipids mediate infectious processes leading to illness. An understanding of these cellular processes will offer hope for future drug development to combat the scourge of cryptococcal meningitis, annually causing the death of over half a million people in Sub-Saharan Africa. Dr Sebolai is also interested in mapping the prevalence and distribution pattern of cryptococcal meningitis in the Free State. This, in turn, will assist health authorities to manage current infections and plan appropriately for potential outbreaks. The Prestige Scholars Programme, with the assistance of the National Research Foundation, will afford Dr Sebolai the opportunity to pursue his research in laboratories in the United States and India in 2012 and 2013.


 Description: 2011 PSP_Louis Holtzhausen Tags: 2011 PSP_Louis Holtzhausen

Dr Louis Holtzhausen, member of the Vice-Chancellor’s Prestige Scholars Programme, has been named by the South African Sports Confederation and Olympic Committee (SASCOC) as team doctor for Team South Africa during the All Africa Games, the largest sports event in Africa. National teams from African countries participated in 23 sports events. As an esteemed South African academic in sports medicine Dr Holtzhausens’ participation was an extension of the work already being done under his supervision at the UFS’s Sports Performance Unit. Many of the athletes who prepared at the Unit were also part of the team. Elite athletes’ illness and injury profiles are one of Dr Holtzhausens’ research focus areas. The exposure to this group in competition was of great value in the identification and development of research niche areas.


 Description: 2011 PSP_ Chantel Swart Tags: 2011 PSP_ Chantel Swart

The South African Society for Microbiology awarded Dr Chantel Swart-Pistor, a Prestige Scholar on the Vice-Chancellor’s elite programme, the top prize for her PhD during a recent gala dinner in Cape Town. Dr Swart-Pistor accomplished a breakthrough in the field of nanotechnology with The influence of mitochondrial inhibitors on zoospore and ascospore development. Her supervisor, Prof. Lodewyk Kock and co-supervisors, Dr Carolina Pohl and Prof. Pieter van Wyk, also stressed the important collaboration with Proff. Hendrik Swart (Physics) and Pieter van Wyk (Centre for Microscopy), which made Dr Swart-Pistor’s work possible. She has presented her work in Beijing (Medichem 2011) and Philadelphia (Biotechnology-2011). She has been invited to return to China in 2012.


 Description: 2011 PSP_ Lizette Erasmus Tags: 2011 PSP_ Lizette Erasmus

Dr Lizette Erasmus, scientific chemist and one of the Vice-Chancellor’s Prestige Scholars, has just returned from a three-month-long research visit to Prof. Hans Niemantsverdriet at the Technical University of Eindhoven in The Netherlands and the University of California, Davis. Dr Erasmus specialises in heterogeneous catalysis. Her visit to Prof. Niemantsverdriet, one of the global experts in the field of surface science, served to round of existing research. In California, Dr Erasmus visited her mentor, Prof. Bruce C. Gates, as part of the objectives of the Rector’s programme for the internationalisation of young researchers. Prof. Gates, an expert in catalysis, could contribute to Dr Erasmus’ research on the characterisation of heterogeneous catalysis and catalytic reactions. In exchange, her expertise in organometallic synthesis added value to Prof. Gates’ existing research. Their continued collaboration gave availed them of the opportunity for interdisciplinary interaction between engineering (Prof. Gates’ speciality) and chemistry, and promises to contribute to increased collaboration between the two universities in future.


 Description: 2011 PSP_Dirk Opperman Tags: 2011 PSP_Dirk Opperman

Dr Dirk Opperman, specialist in structural and evolutionary biology and National Research Foundation Thuthuka Grant holder, joined the Vice-Chancellor’s Prestige Scholars Programme after his postdoctoral work at the Max Planck Institute (KOFO) in Germany. Dr Opperman is the recipient of institutional seed funding to establish a protein crystallisation unit, which in turn led to the donation in 2011 of a multi-million Rand X-ray diffractometer¬ from the University of the Western Cape to complement his existing access to international synchrotrons. Dr Opperman is spending part of 2011 at the University of Exeter (UK) to further his research into the three-dimensional structures of specific enzymes and their trajectories of evolution to specific functions.


 Description: 2011 PSP_Abiodun Ogundeji Tags: 2011 PSP_Abiodun Ogundeji

Abiodun Ogundeji is a member of the Vice-Chancellor's Prestige Scholars Programme. Abiodun's work was recently recognised when he and his co-authors received an award for the best contributed paper at the 49th annual conference of the Agricultural Economics Association of South Africa on the topic, Impact of climate change on planning and dealing with flood disasters in South Africa: A case study of Soweto on Sea. The paper was co-authored by Prof. Giel Viljoen from our Department of Agricultural Economics and Herman Booysen, as well as Gawie du T. de Villiers, Research Associates in the Department of Geography. Abiodun is currently conducting invaluable research on the quantification of the economic value of climate change impacts and the benefits and costs of adaptation in South Africa.

 

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