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17 March 2021 | Story Karen Venter
As illustrated in the infographic, the input from engaged activities delivered by the UFS resulted in 285 engaged-activity outputs, of which the majority constituted engaged citizenship, followed by engaged research, and then engaged learning and teaching.


View infographic here

At the University of the Free State (UFS), engaged scholarship activities are guided by the vision of being a research-led, student-centred, and regionally relevant university, focused on development and social justice.

For enactment of this vision, the UFS invests physical resources and funding, as well as staff and student hours to contribute to nation building. 

Demonstrating the heart of strategic partnerships

Engaged scholarship demonstrates the heart of strategic partnerships, where agreements are grounded in shared goals, designed and agreed upon in unity for socio-economic renewal to improve people’s living conditions, contributing to societal well-being. It links the best of the research and teaching skills of staff and students to specific needs of the community, including civil society, the private sector, government, non-governmental organisations, and enterprises. 

Democratic knowledge co-creation emerges from engaged learning and teaching, engaged research, and engaged citizenship through interaction between the institution, its staff and students, and the community. 

The curriculum, engaged research efforts, engaged learning and teaching, and graduate attributes are all enriched through collaborative and reciprocal learning activities. As illustrated in the infographic, the input from engaged activities delivered by the UFS resulted in 285 engaged-activity outputs, of which the majority constituted engaged citizenship, followed by engaged research, and then engaged learning and teaching. 

Deep understanding of socio-economic and environmental challenges

Our students participate in community-engaged service-learning, leading to knowledge acquisition and a deep understanding of socio-economic and environmental challenges in mutual solidarity with the community. Service-learning also gives rise to the acceptance and understanding of diverse cultures and races and advances the ability to interact meaningfully with diverse people from different backgrounds. 

Community-engaged learning increases awareness of own biases and stereotypes along the dimensions of race, ethnicity, culture, gender, sexual orientation, socio-economic status, age, physical abilities, religious beliefs, political beliefs, or other ideologies. By transcending their own comfort zones, combined with collaborative learning with diverse groups, students can gain greater appreciation of the strengths and capacities of diverse groups in the community. 

The UFS invests physical resources and funding, as well as staff and student hours to contribute to nation building. – Karen Venter

Engaged scholarship also embraces the inculcation of citizenship and the social responsibility of the UFS to society by giving effect to one of the key ‘public good’ dimensions of the UFS. 

News Archive

Nuclear Medicine on the forefront of cancer research
2017-07-10

Description: Nuclear Medicine on the forefront of cancer research Tags: Nuclear Medicine, cancer research, Dr Je’nine Horn-Lodewyk’s, tumour detection method, cancer, Department of Nuclear Medicine 

Dr Je’nine Horn-Lodewyk’s tumour detection method
could be the cost-effective breakthrough needed to decrease
the mortality rate in breast cancer patients.
Photo: Anja Aucamp

The field of Nuclear Medicine in South Africa and the rest of the world are expanding rapidly due to the development of hybrid cameras and new radiopharmaceuticals. These developments have a huge impact on the diagnosis and therapy of cancer.

The most advanced of these cameras, Positron emission tomography combined with normal CTs (PETCT), are not yet widely available in South Africa due to the cost of the cameras and the radiopharmaceuticals. A more cost-effective alternative can be of great benefit. To achieve this, the focus should be on developing new radiopharmaceuticals that can be used with the current cost-effective gamma cameras, according to University of the Free State researcher, Dr Je’nine Horn-Lodewyk from the Department of Nuclear Medicine.

Fluorodeoxyglucose (18F-FDG), a radiolabelled glucose analogue, is currently the radiopharmaceutical most commonly used in PET/CT imaging for mainly oncology indications. Although it is considered the gold standard for imaging in several malignancies, it does have certain disadvantages. An 18F-FDG PET/CT diagnostic imaging study can cost between R25 000 and R35 000 for a single patient in the private sector. The 18F-FDG is also more radioactive, which requires much stricter handling and shielding to avoid high radiation dosages to staff and patients.

Successful research potential innovative solution
In the search for the ideal radiopharmaceutical for tumour detection, the South African National Nuclear Energy Corporation (Necsa) developed a local synthesis process for ethylenedicysteine-deoxyglucose (EC-DG). EC-DG is also a glucose analogue similar to FDG. They succeeded in labelling the compound with Technetium-99-metastable-pertechnetate (99mTcO4-), the most common nuclear medicine isotope used for approximately 95% of nuclear medicine procedures, creating 99mTc-EC-DG.

In partnership with Dr Horn-Lodewyk, this compound was successfully used in various animal models and clinical scenarios, resulting in approval by the Medicine Control Council to use it in a human study. Research is also planned in order to investigate diagnostic accuracy in other cancers like lymphoma.  The end result of this research can produce a radiopharmaceutical that is cost effective, does not require the use of costly specialised equipment, has no significant side-effects, no special patient preparation, renders late imaging possible, and has decreased radiation risks.

Dr Horn-Lodewyk is grateful for the support of her mentor, Prof Anton Otto, as well as Dr Gert Engelbrecht, Head of the Department of Nuclear Medicine, Prof Jan Rijn Zeevaart from North-West University’s Preclinical Drug Development Platform and Necsa, and Judith Wagener from Necsa. This innovative research would also not have been possible without the financial assistance of Dr Glen Taylor and Eleanor van der Westhuizen in the Directorate of Research Development.

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