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01 November 2021 | Story André Damons
Digital Scholarship Centre DSC
The recently established Digital Scholarship Centre (DSC) at the UFS is playing an important role in contributing to the development of a collaborative research culture at the university.

The recently established Digital Scholarship Centre (DSC) at the University of the Free State (UFS) is playing a pivotal role in contributing to the development of a collaborative research culture at the university – from cross-faculty and international collaboration to support and administrative services for research.

The DSC was established after an investigation by the Library and Information Services (LIS) to determine the need for digital scholarship support in order to help escalate research output and quality and to support the institutional strategic aim of being a research-led university. The investigation clearly revealed that digital scholarship services would have a significant impact on the UFS' strategic purposes.

Cornelle Scheltema-Van Wyk, Manager of the DSC, says the centre is there to help increase research output, research visibility and impact, and ultimately, the reputation of the university as a research-led institution. “And we do this within the digital scholarship environment (which exists because of digital technology, the internet, and open scholarship), providing researchers with support to use digital methods to enhance their work,” says Scheltema-Van Wyk. 

A pilot project for the DSC was run last year by a work group consisting of representatives from LIS, the Directorate of Research Development (DRD), and ICT Services. An acting manager was appointed, and a web presence was created for the DSC. 

Assistance for researchers
It was clear from the investigation that the research community at the university needed help navigating the digital landscape, determining what services and support systems exist, and how to find, access, and use them. The investigation revealed that researchers are looking for
  • a one-stop shop for research support;
  • increased awareness of services at the university;
  • information, guidance, and training for researchers to enable them to discover, request, and use research support services and digital technologies;
  • creating a strong online presence, while also providing a physical hub with equipment that many researchers cannot afford, as well as a ‘haven’ with an ‘inspiring atmosphere’ to do research when offices become too distracting due to administrative tasks and students;
  • assistance with creating and using collaborative online environments for collaborative research projects;
  • assistance with the open science environment, specifically with regard to open access publishing, funding for open access publishing, and open methods in research; and
  • support for research data management, specifically the development of a research data policy and a data repository at the university.

The centre, which has its roots in the digital, open, and networked environment, also helps to maximise the effectiveness of scarce and limited resources by minimising duplication, not only in research practice with the help of research data management, for example, but also at support level with knowledge of the institutional research environment and where resources can be shared. DSC works to maintain awareness of all relevant resources and can assist with connection and coordination. It also provides information, guidance, training, support services for digital scholarship as well as technology and software, consultation, spaces, and referrals to services such as high-performance computing. 

According to Scheltema-Van Wyk, the benefit of digital scholarship services with a main hub to act as coordinator and consolidator is that the hub has a wider view of the research environment at the institution throughout the research cycle. This includes the planning stages of a research project where a researcher needs to acquire equipment, to data collection and analysis in a digital world, to the preservation of research, and publication in a new scholarly communication environment.

The pilot projects

The UFS has a good foundation of capabilities when it comes to existing research support services for digital scholarship and has developed these capabilities over the past ten years. This includes the High-Performance Computing unit in ICT Services, innovation support by the DRD via KovsieInnovation, and digitisation, digital collections infrastructure, electronic publishing, and repository services at LIS. These support services are very successful from a production standpoint, but the success of visibility and engagement with these services at the institution is more varied.

“The pilot projects illustrated the benefits of the DSC, where researchers were able to contact the centre with questions ranging from how to install research software on their computers, the process of acquiring mobile applications for research purposes (the DSC liaised with Finance to create a process), to setting up online academic seminars and getting third-party applications to work with university resources,” says Scheltema-Van Wyk. 

The knowledge gained from these service requests has already provided the DSC with a broader knowledge of the research environment at the university and allowed recommendations for collaboration and the sharing of resources and expertise in the community.

The DSC uses a hub-and-spoke service model. This model includes a strong central node that links to many other resources. Knowledge, expertise, staff, and services are embedded in academic departments, interdisciplinary units (for example, the newly established Interdisciplinary Centre for Digital Futures), libraries and other service points around the university, which are connected and coordinated through this central node.

The advantage of this model is that it allows growth to take place organically. Services and expertise develop where needed, rather than researchers depending on a centralised unit that may lack the resources to meet ever-evolving digital scholarship needs. Distributed knowledge and skills, however, make it difficult to identify where to go for specific services, training, and assistance. The DSC as a central hub combats the confusion this may cause, linking to the various spokes at the institution.

Prof Corli Witthuhn, Vice-Rector: Research and Internationalisation, says the DSC is at the forefront of providing support to our world-leading researchers on the latest developments in the digital research arena. We are committed to continuing our cutting-edge support and novel approaches to developing the UFS as a research-led university.

News Archive

UFS study on cell development in top international science journal
2008-09-16

A study from the University of the Free State (UFS) on how the change in the packaging of DNA with cell development influenced the expression of genes, will be published in this week’s early edition of the prestigious international, peer-reviewed science journal, the Proceeding of the National Academy of Sciences of the USA (PNAS).

The PNAS journal has an impact factor of 10, which means that studies published in the journal are, on average, referred to by ten other scientific studies in a two year period. The South African Journal of Science, by comparison, has an impact factor of 0.7.

The UFS study, funded by the Wellcome Trust and the National Research Foundation (NRF), looked at how the change in the packaging of DNA with cell development influenced the expression of genes. It is very relevant to research on stem cells, an area of medicine that studies the possible use of undifferentiated cells to replace damaged tissue.

Prof. Hugh Patterton, of the Department of Microbial, Biochemical and Food Biotechnology at the UFS, who led the study, said: "We are extremely proud of this study. It was conceived in South Africa, it was performed in South Africa, the data were analysed in South Africa, and it was published from South Africa."

When a gene is expressed, the information encoded in the gene is used to manufacture a specific protein. In eukaryotes, which include humans, there is approximately 1m of DNA, containing the genes, in every cell. This length of DNA has to fit into a cell nucleus with a diameter of only about 10 micrometer. In order to fit the DNA into such a small volume, eukaryotic cells wrap their DNA onto successive protein balls, termed nucleosomes. Strings of nucleosomes, resembling a bead of pearls, is folded into a helix to form a chromatin fiber. The study from the UFS investigated how the binding of a specific protein, termed a linker histone, that binds to the length of DNA between nucleosomes, influenced the formation of the chromatin fiber and also the activity of genes.

"We found that the linker histone bound to chromatin in yeast, which we use as a model eukaryote, under conditions where virtually all the genes in the organism were inactive. It was widely believed that the binding of the linker histone caused the inactivation of genes. We studied the relationship between the amount of linker histone bound in the vicinity of each gene and the expression of that gene for all the genes in yeast, using genomic techniques. We made the surprising discovery that even through the linker histone preferentially bound to genes under conditions where the genes were shut off, this inactivation of genes was not caused by the binding of the linker histone and folding of the chromatin,” said Prof. Patterton.

He said: “Instead our data strongly suggested that the observed anti-correlation was due to the movement of enzymes along the DNA molecule, involved in processing the information in genes for the eventual manufacture of proteins. This movement of enzymes displaced the linker histones from the DNA. This finding now requires a rethink on aspects of how packaging of DNA influences gene activity."

Prof. Patterton said that his research group, using the Facility for Genomics and Proteomics as well as the Bioinformatics Node at the UFS, was currently busy with follow-up studies to understand how other proteins in nucleosomes affected the activities of genes, as well as with projects to understand how chemicals found in red wine and in green tea extended lifespan. "We are certainly having a marvelous time trying to understand the fundamental mechanisms of life, and the UFS is an exciting place to be if one was interested in studying life at the level of molecules," he said.


Media Release
Issued by: Lacea Loader
Assistant Director: Media Liaison
Tel: 051 401 2584
Cell: 083 645 2454
E-mail: loaderl.stg@ufs.ac.za  
18 September 2008
 

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