Latest News Archive

Please select Category, Year, and then Month to display items
Previous Archive
01 October 2021 | Story Lunga Luthuli and Vicky Simpson | Photo Supplied
Anton Engelbrecht _ Farmovs researcher
Anton Engelbrecht, FARMOVS Bioanalysis Specialist.

“At FARMOVS, we have the opportunity to work with the world’s top pharmaceutical companies, where we form part of the evaluation of labelled and/or conjugated antigens and antibodies that are developed for accurate quantification of endogenous and pharmaceutical compounds. Alternatively, commercially available kits and reagents are also used for the same purpose if the sponsor cannot supply the customised antigens/antibodies. The developed assay methods are put through a rigorous validation assessment to confirm the selectivity, sensitivity, and robustness of the assay,” says Anton Engelbrecht, FARMOVS Bioanalysis Specialist. 

FARMOVS, affiliated to the University of the Free State and operating from the Bloemfontein Campus, is a leading clinical research organisation (CRO) with a unique advantage. As the only on-site ISO15189-accredited and GLP-certified pharmacokinetic laboratory on the African continent, with numerous successful inspections by leading international regulators, it offers the highest quality bioanalytical services in a variety of biological matrices for the development of pharmaceutical products.

Engelbrecht says: “The team of bioanalytical experts thrives on the excitement generated by new discoveries that lead to better treatment of a variety of physiological diseases.”

Advanced technology backed by 47 years of bioanalytical experience

The clinical research organisation prides itself on advanced technology, backed by 47 years of bioanalytical experience. It has developed more than 580 validated analytical methods that adhere to the International Council for Harmonisation and the US Food and Drug Administration (FDA) guidelines. FARMOVS’ analytical methods have been used in more than 3 000 pre-clinical and clinical trials, contributing to the manufacturing of pharmaceutical drugs that are now used by households across the globe.

At FARMOVS, Engelbrecht says, it is a “world filled with novel methods of analysis and subsequent technological integration that expands the horizons of clinical research forming an important part of the discovery and production of new life-saving medicines that is constantly improving the quality of life of people all over the world”.

Engelbrecht says: “New technology and innovation should be the building blocks of any laboratory, and among these are the three fastest sample production members of our Immunochemistry Laboratory team – the STARLet pipettors.”

“We chose the Microlab® STARLet apparatus by Hamilton, because of its ability to perform sample analysis in large quantities at a greater speed by means of robotic pipetting and robotic automated microplate reading, which is a semi-automated process.”

He shared his excitement about improvements in the field of immunoassay development for the purposes of pharmaceutical analysis. This involves the preparation of unique immunoanalytical reagents, analysis of new categories of compounds, methodology, and instrumentation. The most important examples in this field are the continuous development of bead-based immunoassays.

Staying competitive in the industry

Immunoassay methods, such as radioimmunoassay (RIA) and enzyme immunoassay (EIA), among others, are also used at FARMOVS to analyse macromolecules for clients. “The RIA method is used for the determination of several pharmaceutically important compounds in biological fluids. RIA requires a sample containing the antigen of interest, a complementary antibody, and a radiolabelled version of the antigen. To increase the selectivity of an assay, all samples are pre-treated to eliminate high molecular weight endogenous matrix components, including anti-drug antibodies,” explains Engelbrecht.

Although FARMOVS has adequate technology to provide market-related results, the plan is to expand the team to include a multiplex platform that is a sensitive, fully automated immunoassay platform with multiplexing and custom assay capability. “This will pave the way to use an even more sensitive method to quantify biomarkers in the fields of oncology, neurology, cardiology, inflammation, and infectious disease. We aim to remain competitive in our industry, so naturally we must recruit the brightest and most evolved to join the team,” he says.

News Archive

Beauty personified through written word
2016-07-29

Description: Zubeida Jaffer Tags: Zubeida Jaffer

Dr Thozama April, University of Fort Hare
historian, Zubeida Jaffer, current Writer-in-Residence
in the Department of Communication Sciences
at the UFS and author of Beauty of the Heart:
The life and times of Charlotte Mannya Maxeke
and Prof Jonathan Jansen, Vice-Chancellor and Rector
of the UFS at the book launch of Zubeida Jaffer.
Photo: Rulanzen Martin

“It is quite easy to write a book in a professional capacity but very difficult to write a book from the heart.”

These were the words of Prof Jonathan Jansen, Vice-Chancellor and Rector of the University of the Free State (UFS), at the launch of Beauty of the Heart: The life and times of Charlotte Mannya Maxeke by Zubeida Jaffer, the current Writer-in-Residence in the Department of Communication Sciences at the UFS.

Perseverance and dedication yields results

Writing a book from the heart is exactly what Jaffer, an award-winning South African journalist and author, set out to do. “When you make the choice to write a story, you need to be very dedicated,” she said.

As this is Jaffer’s third book, one would think that she would have no difficulty in putting pen to paper. On the contrary, she mentioned that it was, in fact, the hardest book she has written because the narrative was not easy to get hold of.

“I wanted Charlotte’s voice to come through, and it took my team and I three years of research and writing,” she said.

Maxeke’s story helps to shape South African society

The three-person panel, hosted by the UFS Sasol Library and SUN MeDIA, and chaired by Prof Jansen, included Jaffer and Dr Thozama April, University of Fort Hare historian who had done her PHD thesis on Maxeke.

Dr April said that Maxeke’s life story is an inspiring one, as it encourages a rethinking of established narratives. “These established narratives have made it possible for historians and researchers to write about the shaping of South African society,” she said.

We use cookies to make interactions with our websites and services easy and meaningful. To better understand how they are used, read more about the UFS cookie policy. By continuing to use this site you are giving us your consent to do this.

Accept