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28 October 2021 | Story Prof Sethulego Matebesi | Photo Sonia Small (Kaleidoscope Studios)
Dr Sethulego Matebesi
Prof Sethulego Matebesi is an Associate Professor and Head of the Department of Sociology at the University of the Free State (UFS)

Opinion article by Prof Sethulego Matebesi, Associate Professor and Head of Department of Sociology, University of the Free State.
When a catastrophic accident cuts the first manned mission to Jupiter’s moons short in the Astronaut: The Last Push a 2012 American science fiction film – Michael Forrest, the sole remaining astronaut, must endure the three-year return trip to Earth alone. Similarly, how will the next five-year journey of local governance in South Africa manifest itself? Again, I reckon the responses from citizens will vary widely: from widespread cynicism to hope for a better future and from distrust of a dysfunctional system to the belief that service delivery will improve.

In an all-too-familiar scenario, political party campaigns have been littered with promises of how they best represent and advance voters’ interests. In doing so, two helpful facts about these campaigns emerge. The first is that the ANC, DA, EFF, and FF+ have realised that local contexts differ significantly and have framed their messages accordingly. A cursory glance at the broadcastings of these customised campaigns reveals that they aim to provide a safe psychological outlet for community-level concerns. The second is that, in general, the election messaging and adverts of the ANC ranged from apologies to bold statements about who wields power to change the face of local governance. Opposition parties focused on improving the local government system notoriously known for the disregard of citizens’ needs and providing an active voice for the voiceless.

And guess what?

Political parties and candidates may mobilise constituencies as much as they can. However, the next five years of local governance require a significant departure from its status of dysfunctionality to a competent, legitimate political institution that produces satisfactory political outcomes. This legislative and moral mandate depends entirely on local participation in elections.

The three dimensions of increasing voter participation

Better and more meaningful political participation in elections remains a concern in South Africa. In a report for the Ford Foundation, Hahrie Han, a political science professor at the University of California, proposes a framework that details increasing participation and making it more meaningful.

Firstly, people must be able to participate. Declaring election day as a public holiday, President Cyril Ramaphosa removed an important barrier to participation. While some may believe that election day will be just another public holiday, for others – particularly those who are working – there is no need to weigh up whether to take leave for a cause that will not significantly change their lives. Furthermore, the Independent Electoral Commission (IEC) has demonstrated a sense of moral urgency by drawing unprecedented public attention to their voting processes and procedures to protect voters and election officials from spreading the virus at the polling stations.

Secondly, people must want to participate. Here, political parties and election candidates should not take voting as a taken-for-granted part of the repertoire of residents’ political activities. Election campaigns – both online (internet) and offline (door-to-door engagements, posters, and billboards) remain a powerful medium to improve visibility and deliver messages to solicit interest from citizens. But once these campaigns conclude, still, it remains an individual’s choice to want to participate in the elections. While it is difficult to assess the level of voter engagement with the election campaigns under COVID-19 restrictions, the general political climate in South Africa seems to be conducive for free and fair elections. Yet political assassinations continue to cast a dark shadow over the local government elections. This cruel feature of political life in the country serves as an ultimate intimidation tactic. It denies candidates the right to stand for election and citizens to choose their preferred public representatives.

Thirdly, Hahn argues that for people to want to participate in the political process, their participation must matter. Therefore, aside from building a sense of agency and encouraging greater participation in elections, people still need to be convinced that their vote counts and influences decisions at the local level, where voters have the chance to participate directly in the election of local councillors.

Disrupting the balance of power in local councils 

Regardless of the challenges it faces, the ANC remains in pole position to retain most of the local councils it leads. I believe there is much to be discontented about, but opposition parties – including civic forums – have yet to build the power to break the stranglehold the ANC has on elections – and that is no small task.

Interestingly, in contrast to the DA, the ANC has paradoxically avoided announcing their mayoral candidates in direct response to prevent the electoral backlash it received in the metros during the 2016 local government elections. Yet, except for a few local councils in several provinces, the metros are precisely where the most significant disruption to the balance of power will occur. 

Whether political parties will deal with the standoffs of coalition politics in hung councils, while broaching complex issues, remains a concern for South Africans. But elections remain an excellent opportunity for citizens to participate and influence local political decision-making.

News Archive

Research contributes to improving quality of life for cancer patients
2016-11-21

Description: Inorganic Chemistry supervisors  Tags: Inorganic Chemistry supervisors

Inorganic Chemistry supervisors in the Radiopharmacy
Laboratory during the preparation of a typical complex
mixture to see how fast it reacts. Here are, from the left,
front: Dr Marietjie Schutte-Smith, Dr Alice Brink
(both scholars from the UFS Prestige
Scholar Programme), and Dr Truidie Venter (all three
are Thuthuka-funded researchers).
Back: Prof André Roodt and Dr Johan Venter.
Photo: Supplied

Imagine that you have been diagnosed with bone cancer and only have six months to live. You are in a wheelchair because the pain in your legs is so immense that you can’t walk anymore – similar to a mechanism eating your bones from the inside.

You are lucky though, since you could be injected with a drug to control the pain so effective that you will be able to get out of the wheelchair within a day-and-a-half and be able to walk again. Real-life incidents like these provide intense job satisfaction to Prof André Roodt, Head of Inorganic Chemistry at the University of the Free State (UFS). The research, which is conducted by the Inorganic Group at the UFS, contributes greatly to the availability of pain therapy that does not involve drugs, but improves the quality of life for cancer patients.

The research conducted by the Inorganic Group under the leadership of Prof Roodt, plays a major role in the clever design of model medicines to better detect and treat cancer.

The Department of Chemistry is one of approximately 10 institutions worldwide that conducts research on chemical mechanisms to identify and control cancer. “The fact that we are able to cooperate with the Departments of Nuclear Medicine and Medical Physics at the UFS, the Animal Research Centre, and other collaborators in South Africa and abroad, but especially the methodology we utilise to conduct research (studying the chemical manner in which drugs are absorbed in cancer as well as the time involved), enhances the possibility of making a contribution to cancer research,” says Prof Roodt.

Technique to detect cancer spots on bone
According to the professor, there are various ways of detecting cancer in the body. Cancer can, inter alia, be identified by analysing blood, X-rays (external) or through an internal technique where the patient is injected with a radioactive isotope.

Prof Roodt explains: “The doctor suspects that the patient has bone cancer and injects the person with a drug consisting of an isotope (only emits X-rays and does no damage to tissue) that is connected to a phosphonate (similar to those used for osteoporosis). Once the drug is injected, the isotope (Technetium-99m) moves to the spot on the bone where the cancer is located. The gamma rays in the isotope illuminate the area and the doctor can see exactly where treatment should be applied. The Technetium-99m has the same intensity gamma rays as normal X-rays and therefore operates the same as an internal X-ray supply.” With this technique, the doctor can see where the cancer spots are within a few hours.

The same technique can be used to identify inactive parts of the brain in Alzheimer patients, as well as areas of the heart where there is no blood supply or where the heart muscle is dead.

Therapeutic irradiation of cancer
For the treatment of pain connected with cancer, the isotope Rhenium-186 is injected. Similar to the manner in which the Technetium-99m phosphonate compound is ingested into the body, the Rhenium-186 phosphonate travels to the cancer spots. Patients thus receive therapeutic irradiation – a technique known as palliative therapy, which is excellent for treating pain. A dosage of this therapy usually lasts for about two months.

The therapy is, however, patient specific. The dosages should correspond with the occurrence and size of cancer spots in the patient’s body. First, the location of the cancer will be determined by means of a technetium scan. After that, the size of the area where the cancer occurs has to be determined. The dosage for addressing total pain distribution will be calculated according to these results.

Technique to detect cancer spots on soft tissue
Another technique to detect cancer as spots on bone or in soft tissue and organs throughout the body is by utilising a different type of irradiation, a so-called PET isotope. The Fluor-18 isotope is currently used widely, and in Pretoria a machine called a cyclotron was produced by Dr Gerdus Kemp, who is a former PhD graduate from the Inorganic Research Group. The F-18 is then hidden within a glucose molecule and a patient will be injected with the drug after being tranquillised and after the metabolism has been lowered considerably. The glucose, which is the ‘food' that cancer needs to grow, will then travel directly to the cancer area and the specific area where the cancer is located will thus be traced and ‘illuminated’ by the Fluor-18, which emits its own 'X-rays'.

In the late 80s, Prof Roodt did his own postdoctoral study on this research in the US. He started collaborating with the Department of Nuclear Medicine at the UFS in the early 90s, when he initiated testing for this research.

Through their research of more than 15 years, the Inorganic Group in the Department of Chemistry has made a major contribution to cancer research. Research on mechanisms for the detection of cancer, by designing new clever chemical agents, and the chemical ways in which these agents are taken up in the body, especially contributes to the development in terms of cancer therapy and imaging, and has been used by a number of hospitals in South Africa.

The future holds great promise
Prof Roodt and his team are already working on a bilateral study between the UFS and Kenya. It involves the linking of radio isotopes, as mentioned above, to known natural products (such as rooibos tea), which possess anti-cancer qualities.

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