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22 October 2021 | Story Leonie Bolleurs | Photo Charl Devenish
UFS staff and students who attended the Talloires Network Leaders Conference, were from the left: Rina Widd, Occupational Therapy Student Association; Lyshea Mapaike, Social Work Student Association; Gernus Terblanche, SRC member for Civic and Social Responsibility; Relebohile Sebetoane, Eco-alliance Association; and Karen Venter.

The University of the Free State (UFS) Directorate Community Engagement was recently (30 September to 3 October 2021) among the 419 institutions and 79 countries that participated in the (virtual) Talloires Network Leaders Conference (TNLC2021).

The conference, which was a global gathering of higher education leaders and students from all regions of the world, focused on Global Institutions, Local Impact: Power and Responsibility of Engaged Universities. 

Some of the highlights of the conference were the sessions titled: Global Universities, Local Impact: Roles and Responsibilities of Universities with Philip Cotton, Head of the Mastercard Foundation Scholars Programme; and the keynote address by Secretary John Kerry, US Special Envoy on Climate, titled What can we learn from the pandemic that helps (or hinders) addressing climate change? 

Cotton, believing in the power of compassion in the transformation of young people, said: “It is possible that the more you become the kind of university that matters to our young people, because you connect with the poorest and the hardest to reach, and those most harshly oppressed by climate change, then the more serving, humane, engaged and compassionate you become. 

He added: “Listen to the young people, they are telling us what is wrong with our systems, and the solutions are in their hands.”

Addressing global challenges

According to Karen Venter, Head of the Service-Learning Division in the UFS Directorate of Community Engagement, the event provided the opportunity to critically reflect on the power and responsibility of engaged universities, to collaborate and connect in partnership with communities, and to address local and global challenges. 

“Participants shared knowledge, ideas, case studies, and built collaborations for action on important and interrelated issues, including pandemic recovery and resilience; conflict and inequality; climate justice; assessing engagement; and community engagement futures,” she says.

Some of the UFS attendees remarked that they were amazed by the work being done worldwide. They were spurred on and inspired to not only improve their modules, but also their work in the community.

Besides being exposed to world-class leaders on issues that matter, the conference also maximised engagement and forged connections on a local level. The UFS hosted a delegation of 19 academics, students, and community members from Rhodes University (RU), who not only attended the conference with them, but also an additional pre-conference digital storytelling knowledge-sharing workshop, and a mini-Engaged Learning Festival.

RU also won the McJanet Prize for Global Citizenship, following a review of 28 nominations from 15 countries and 10 finalists from 8 countries.

Sharing best practices

The digital storytelling workshop (where information about projects and people are communicated in short, multimedia tales, told from the heart), according to Venter, rekindled the UFS-RU partnership for sharing local social innovation stories globally through digital storytelling, which was born from the Common Good First EU Erasmus +-funded project.

During the learning festival, the two universities shared best practices on some of the community programmes in which they are involved, including UFS presentations from Enactus for social entrepreneurship, and the No Hungry Student initiative, which involves student residences’ community food gardens. RU reported on their active citizenship (Nine Tenths mentor mentee schools programme) and community-based research projects.

Better together

Besides international conferences such as TNLC2021, and other local engagements to always stay on top of the latest community engagement practices, the UFS and RU are both members of the South African Higher Education Community Engagement Forum (SAHECEF). According to Venter, the UFS-RU partnership showcased how different regional chapters of SAHECEF collaborated as communities of practice to advance the praxis of an engaged scholarship. 

Both the institutions are also involved in the South African Knowledge for Change (K4C) Hub within a K4C Consortium of the UNESCO Chair in Community Based Research and Social Responsibility towards training for community-based researchers in the context of community university research partnerships.

News Archive

UFS study on cell development in top international science journal
2008-09-16

A study from the University of the Free State (UFS) on how the change in the packaging of DNA with cell development influenced the expression of genes, will be published in this week’s early edition of the prestigious international, peer-reviewed science journal, the Proceeding of the National Academy of Sciences of the USA (PNAS).

The PNAS journal has an impact factor of 10, which means that studies published in the journal are, on average, referred to by ten other scientific studies in a two year period. The South African Journal of Science, by comparison, has an impact factor of 0.7.

The UFS study, funded by the Wellcome Trust and the National Research Foundation (NRF), looked at how the change in the packaging of DNA with cell development influenced the expression of genes. It is very relevant to research on stem cells, an area of medicine that studies the possible use of undifferentiated cells to replace damaged tissue.

Prof. Hugh Patterton, of the Department of Microbial, Biochemical and Food Biotechnology at the UFS, who led the study, said: "We are extremely proud of this study. It was conceived in South Africa, it was performed in South Africa, the data were analysed in South Africa, and it was published from South Africa."

When a gene is expressed, the information encoded in the gene is used to manufacture a specific protein. In eukaryotes, which include humans, there is approximately 1m of DNA, containing the genes, in every cell. This length of DNA has to fit into a cell nucleus with a diameter of only about 10 micrometer. In order to fit the DNA into such a small volume, eukaryotic cells wrap their DNA onto successive protein balls, termed nucleosomes. Strings of nucleosomes, resembling a bead of pearls, is folded into a helix to form a chromatin fiber. The study from the UFS investigated how the binding of a specific protein, termed a linker histone, that binds to the length of DNA between nucleosomes, influenced the formation of the chromatin fiber and also the activity of genes.

"We found that the linker histone bound to chromatin in yeast, which we use as a model eukaryote, under conditions where virtually all the genes in the organism were inactive. It was widely believed that the binding of the linker histone caused the inactivation of genes. We studied the relationship between the amount of linker histone bound in the vicinity of each gene and the expression of that gene for all the genes in yeast, using genomic techniques. We made the surprising discovery that even through the linker histone preferentially bound to genes under conditions where the genes were shut off, this inactivation of genes was not caused by the binding of the linker histone and folding of the chromatin,” said Prof. Patterton.

He said: “Instead our data strongly suggested that the observed anti-correlation was due to the movement of enzymes along the DNA molecule, involved in processing the information in genes for the eventual manufacture of proteins. This movement of enzymes displaced the linker histones from the DNA. This finding now requires a rethink on aspects of how packaging of DNA influences gene activity."

Prof. Patterton said that his research group, using the Facility for Genomics and Proteomics as well as the Bioinformatics Node at the UFS, was currently busy with follow-up studies to understand how other proteins in nucleosomes affected the activities of genes, as well as with projects to understand how chemicals found in red wine and in green tea extended lifespan. "We are certainly having a marvelous time trying to understand the fundamental mechanisms of life, and the UFS is an exciting place to be if one was interested in studying life at the level of molecules," he said.


Media Release
Issued by: Lacea Loader
Assistant Director: Media Liaison
Tel: 051 401 2584
Cell: 083 645 2454
E-mail: loaderl.stg@ufs.ac.za  
18 September 2008
 

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