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22 October 2021 | Story Leonie Bolleurs | Photo Charl Devenish
UFS staff and students who attended the Talloires Network Leaders Conference, were from the left: Rina Widd, Occupational Therapy Student Association; Lyshea Mapaike, Social Work Student Association; Gernus Terblanche, SRC member for Civic and Social Responsibility; Relebohile Sebetoane, Eco-alliance Association; and Karen Venter.
The University of the Free State (UFS) Directorate Community Engagement was recently (30 September to 3 October 2021) among the 419 institutions and 79 countries that participated in the (virtual) Talloires Network Leaders Conference (TNLC2021).

The conference, which was a global gathering of higher education leaders and students from all regions of the world, focused on Global Institutions, Local Impact: Power and Responsibility of Engaged Universities. 

Some of the highlights of the conference were the sessions titled: Global Universities, Local Impact: Roles and Responsibilities of Universities with Philip Cotton, Head of the Mastercard Foundation Scholars Programme; and the keynote address by Secretary John Kerry, US Special Envoy on Climate, titled What can we learn from the pandemic that helps (or hinders) addressing climate change? 

Cotton, believing in the power of compassion in the transformation of young people, said: “It is possible that the more you become the kind of university that matters to our young people, because you connect with the poorest and the hardest to reach, and those most harshly oppressed by climate change, then the more serving, humane, engaged and compassionate you become. 

He added: “Listen to the young people, they are telling us what is wrong with our systems, and the solutions are in their hands.”

Addressing global challenges

According to Karen Venter, Head of the Service-Learning Division in the UFS Directorate of Community Engagement, the event provided the opportunity to critically reflect on the power and responsibility of engaged universities, to collaborate and connect in partnership with communities, and to address local and global challenges. 

“Participants shared knowledge, ideas, case studies, and built collaborations for action on important and interrelated issues, including pandemic recovery and resilience; conflict and inequality; climate justice; assessing engagement; and community engagement futures,” she says.

Some of the UFS attendees remarked that they were amazed by the work being done worldwide. They were spurred on and inspired to not only improve their modules, but also their work in the community.

Besides being exposed to world-class leaders on issues that matter, the conference also maximised engagement and forged connections on a local level. The UFS hosted a delegation of 19 academics, students, and community members from Rhodes University (RU), who not only attended the conference with them, but also an additional pre-conference digital storytelling knowledge-sharing workshop, and a mini-Engaged Learning Festival.

RU also won the McJanet Prize for Global Citizenship, following a review of 28 nominations from 15 countries and 10 finalists from 8 countries.

Sharing best practices

The digital storytelling workshop (where information about projects and people are communicated in short, multimedia tales, told from the heart), according to Venter, rekindled the UFS-RU partnership for sharing local social innovation stories globally through digital storytelling, which was born from the Common Good First EU Erasmus +-funded project.

During the learning festival, the two universities shared best practices on some of the community programmes in which they are involved, including UFS presentations from Enactus for social entrepreneurship, and the No Hungry Student initiative, which involves student residences’ community food gardens. RU reported on their active citizenship (Nine Tenths mentor mentee schools programme) and community-based research projects.

Better together

Besides international conferences such as TNLC2021, and other local engagements to always stay on top of the latest community engagement practices, the UFS and RU are both members of the South African Higher Education Community Engagement Forum (SAHECEF). According to Venter, the UFS-RU partnership showcased how different regional chapters of SAHECEF collaborated as communities of practice to advance the praxis of an engaged scholarship. 

Both the institutions are also involved in the South African Knowledge for Change (K4C) Hub within a K4C Consortium of the UNESCO Chair in Community Based Research and Social Responsibility towards training for community-based researchers in the context of community university research partnerships.

Diana Hornby, Director of Community Engagement at Rhodes University and a speaker at the conference, with Karen Venter.
Diana Hornby, Director of Community Engagement at Rhodes University and a speaker at the conference, with Karen Venter.
A group of 45 academics, students, and community members attended the recent virtual Talloires Network Leaders Conference in the UFS Computer Laboratory on the Bloemfontein Campus.
A group of 45 academics, students, and community members attended the recent virtual Talloires Network Leaders Conference in the UFS Computer Laboratory on the Bloemfontein Campus.
UFS Community Gardens.
UFS Community Gardens.

News Archive

Cardiology Unit involved in evaluation of drug for rare genetic disease
2013-01-04

Front from the left, are: Marinda Karsten (study coordinator and registered nurse),
Laumarie de Wet (clinical technologist), Charmaine Krahenbuhl (study coordinator and radiographer),
Lorinda de Meyer (administrator), Andonia Page (study coordinator and enrolled nurse);
back Dr Gideon Visagie (sub investigator), Dr Derick Aucamp (sub investigagtor),
Prof. Hennie Theron, (principal investigator) and Dr Wilhelm Herbst (sub investigator).
Photo: Supplied
09 January 2013


The Cardiology Research Unit at the University of the Free State (UFS) contributed largely to the evaluation of the drug Juxtapid (lomitapide), which was developed by the Aegerion pharmaceutical company and approved by the FDA (Federal Drug Administration). Together with countries such as die USA, Canada and Italy, the UFS’ Unit recruited and evaluated the most patients (5 of 29) for the study since 2008.  

The drug was evaluated in persons with so-called familial homozygous hypercholesterolemia (HoFH).  

Following its approval by the FDA, Juxtapid is now a new treatment option for patients suffering from HoFH. The drug operates in a unique way which brings about dramatic improvements in cholesterol counts.  

According to Prof. Hennie Theron, Associate Professor in the Department of Cardiology at the UFS and Head of the Cardiology Contract Research Unit, HoFH is a serious, rare genetic disease which affects the function of the receptor responsible for the removal of low-density lipoprotein cholesterol (LDL-C) (“bad” cholesterol) from the body. Damage to the LDL receptor function leads to extremely high levels of blood cholesterol. HoFH patients often develop premature and progressive atherosclerosis, which is a narrowing or blockage of the arteries.  

“HoFH is a genetically transmitted disease and the most severe form of hypercholesterolemia. Patients often need a coronary artery bypass or/and aortic valve replacement before the age of 20. Mortality is extremely high and death often occurs before the third decade of life. Existing conventional cholesterol-lowering medication is unsuccessful in achieving normal target cholesterol values in this group of patients.  

“The only modality for treatment is plasmapheresis (similar to dialysis in patients with renal failure). Even with this type of therapy the results are relatively unsatisfactory because it is very expensive and the plasmapheresis has to be performed on a regular basis.  

“The drug Juxtapid, as currently evaluated, has led to a dramatic reduction in cholesterol values and normal values were achieved in several people. No existing drug is nearly as effective.  

“The drug represents a breakthrough in the treatment of familial homozygous hypercholesterolemia. The fact that it has been approved by the FDA, gives further impetus to the findings,” says Prof. Theron.  

In future further evaluation will be performed in other forms of hypocholesterolemia.  

According to Prof. Theron, the findings of the study, as well as the recent successful FDA evaluation, once again confirms the fact that the UFS’ Cardiology Contract Research Unit is doing outstanding work.  

Since its inception in 1992, the Unit has already been involved in more than 60 multi-centre, international phase 2 and 3 drug studies. Several of these studies, including the abovementioned study, really affected the way in which cardiology functions.  

The UFS’ Cardiology Contract Research Unit is being recognised nationally and internationally for its high quality of work and is constantly approached for their involvement in new studies.  

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