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16 September 2021 | Story Nonsindiso Qwabe | Photo Supplied
Dr Samantha Potgieter.

As COVID-19 vaccines continue to be a topical issue in South Africa and indeed in the world itself, the Department of Human Resources held a webinar for the UFS community on 10 September that delved deeper into the questions surrounding the vaccine. 

Dr Samantha Potgieter, infectious disease expert at the Universitas Academic Hospital and affiliated Lecturer in the Department of Internal Medicine at the University of the Free State, addressed some commonly raised concerns about the COVID-19 vaccine and how it affects us.

Dr Potgieter started off by saying that coronaviruses have been causing outbreaks among humans for millennia. While COVID-19 is relatively mild and self-limiting in 80% of patients, 20% of patients are at risk of developing severe disease.
She said before a vaccine could be introduced to a population, it had to go through rigorous testing and clinical trials. Only once safety has been confirmed, it can be released and distributed. 

“This process usually takes about ten years; this is what we are used to. But it has happened much quicker for the COVID-19 vaccine, and I think this is a fact that many people misinterpret – that the evidence might not be that robust, which is certainly not the case. COVID-19 vaccines have gone through all this rigorous testing, thousands of patients had volunteered for trial testing studies. The point is that we already had the technology, vaccination is not something new to humans. So, these preclinical trials were able to happen very quickly, and because of the large number of infections and because the focus of the entire world was on finding a cure, it was a very set process to get these trials through the adequate phases.” 

She said the COVID-19 vaccine was approved by national regulators, manufactured to exacting standards, and only thereafter distributed – as is the case for all drugs released into the market.

How does the vaccine work?

Dr Potgieter said the vaccine works by producing antibodies against the COVID-19 virus. If you are infected with the COVID-19 virus after getting vaccinated, these antibodies bind to the virus and stop it from replicating.

“When you get infected with a disease such as COVID-19, natural antibodies are produced by the immune system to fight the disease. If you get infected again, the immune system will remember how to respond, and quickly destroy the virus. A vaccine can do the same, but without the risk of disease from natural infection. Vaccines work by imitating a bacteria or virus using either mRNA in the case of the COVID-19 vaccine, or a dead or weakened version of the bacteria or virus. The vaccine raises the body’s alarm. It trains the body to recognise and fight the virus. When the body encounters the real-deal virus, it is primed and ready to fight for the body’s health.”

She said South Africa had the mRNA vaccine in the form of the Pfizer vaccine, and the adenoviral vector vaccine in the form of the Johnson & Johnson vaccine.

Why should you get the vaccine?

Dr Potgieter said vaccines are safe and effective, and the most compelling reasons for getting vaccinated are the following:

-To protect yourself from severe disease
-To protect those around you who may be at risk of severe disease
-To restore the social and economic platforms of the country, and the world at large.
She said that while the vaccine does not prevent you from getting COVID-19, it offers better protection against the development of severe disease, and vaccinated people had 50% less chance of spreading the virus.
The most common side effects of the vaccine are the following:
-Pain at the injection site
-Swollen lymph nodes
-Fever
-Fatigue
-Headache
-Myalgia (muscle pain)

“These are indications that the immune system is mounting a response. When it mounts a response, it produces antibodies,” she said.

Answers to commonly asked questions are the following:

1. Can the vaccine alter my DNA?
“No, it goes nowhere near the nucleus of the cell.”

2. What happens when you get COVID in between the first and second doses?
“Some protection is conferred after the first dose, but maximum protection is conferred two weeks after the second dose. Vaccination is still advised.” 

Dr Potgieter said patients who were between vaccinations still show better recovery results than those without.

3. What about natural immunity?
“Natural immunity might confer better protection, but it runs the risk of severe disease. Yes, immunity can be gained through natural immunity, it can be gained through vaccination, and it can certainly be gained by a combination of the two.”

4. What about long-term side effects?
“Serious side effects that cause long-term health problems following any vaccination are very rare, including the COVID-19 vaccination.”

To get the answers to more of your questions, the webinar can be accessed via the following link: https://event.webinarjam.com/go/replay/43/053q6a8vay9a0qa2

News Archive

UFS awards its innovative thinkers
2009-11-18

Here are, from the left: Prof. Van Wyk with first-prize winners Precious Setlaba and Themba Motsoeneng and Prof. Muriel Meiring, the students’ promoter.
Photo: Stephen Collett


The University of the Free State (UFS) recently announced the winners of the Innovation Fund Competition. This national competition, which is organised by the Department of Science and Technology aims to promote entrepreneurship through the commercialisation of the innovative ideas of young entrepreneurs.

Every participating educational institution first has an in-house competition in which a total prize money of R100 000 is at stake. At the UFS 14 business plans from students were received and evaluated by six external adjudicators. The three winners now have to take part in Phase II of the competition where 60 competitors from 20 universities will compete. The winners of the National Competition will receive prizes of up to R300 000. This money must be used for the development of the innovative idea with which the prize was won.

The first prize in the UFS’s Innovation Fund Competition of R50 000 was won by Themba Motsoeneng and Precious Setlaba from the Department of Haematology for the development of low-cost diagnostic assays for thrombotic diseases and bleeding disorders with the aim of supplying these test assays at a much lower cost to pathology laboratories all over the country. “This exciting idea appealed to many of the judges, especially because it can contribute to low cost health care in the country,” says Prof. Gerrit van Wyk, organiser of the Innovation Fund Competition at the UFS. The second prize of R30 000 was won by Charl Jaftha, MSc student in Physics. He has developed a low-cost hearing aid the size of a cigarette box. It contains a microphone and electronics to amplify the sound. The third prize of R20 000 was won by Adriaan Taylor and Jaco Brink, both MBA students. They designed a two-in-one lawnmower that would enable the average gardener with a bulky garden to shred the garden refuse and recycle it through composting or disposal through the normal disposal system. “One judge called this a novel use of existing technology,” says Prof. Van Wyk.
 

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