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20 September 2021 | Story Leonie Bolleurs | Photo Supplied
Prince Matova, a PhD student in the Department of Plant Sciences, has been working on breeding a maize that can resist the fall armyworm (FAW) – a maize-eating pest. Later in September, he will receive the Young Scientist Award from the Plant Mutation Breeding Division of the International Atomic Energy Agency (IAEA) and the Food and Agriculture Organisation of the United Nations (FAO).

Prince Matova, a PhD student in Plant Breeding at the University of the Free State (UFS), received the Young Scientist Award from the Joint Food and Agriculture Organisation of the United Nations (FAO)/International Atomic Energy Agency (IAEA) Division of Nuclear Techniques in Food and Agriculture for excellence in plant mutation breeding.

The IAEA Director-General, Mr Rafael Mariano Grossi, will officially announce the award at the 65th regular session of the IAEA General Conference that will take place later in September this year.

The award is given to scientists younger than 40, who have made a significant contribution and impact in the field of mutation breeding.

Matova, a researcher, research and agronomy manager, and maize and legumes breeder at Mukushi Seeds (Pvt) Ltd in Harare, Zimbabwe, says: “People have seen the little work that I have done, and they were happy with it. That makes me happy too.”

Other contributions

In the ten years collaborating with the IAEA, practising mutation breeding, Matova – who believes innovative thinking and self-motivation to be contributing factors to a successful scientist – has also been recognised for other outstanding contributions. These include the release of a cowpea mutant variety in 2017 and its wide dissemination across Zimbabwe, as well as the modernisation of the maize and cowpea national breeding programmes. He has also contributed two publications and appeared twice at IAEA Plant Mutation Breeding symposia. Furthermore, Matova has trained other scientists and fellows across Africa and collaborated with centres of excellence in plant breeding, research, and development.

Growing up, he never guessed that he would one day become an agricultural scientist. Matova was, however, very good at biology and believes that this is one of the reasons why he ended up in crop science. “I am enjoying every moment of it. I love innovativeness and inventions and I view hybrid maize variety development as the greatest innovation in plant breeding. Working for Mukushi Seeds is inspiring; I have a young and dedicated team and the environment allows me to explore my full potential.”

“I feel science solves problems and every day as I do my breeding work, I have this desire to achieve greatness by developing a super maize hybrid,” he says.

Displaying excellence

For the past three to four years, Matova has been working to breed maize varieties that can resist fall armyworm (FAW) – a maize-eating pest. He says the pest has caused significant maize crop yield and economic losses across Africa.

More than 300 million smallholder farmers across sub-Saharan Africa rely on maize for food and livelihoods. “These farmers have limited capacities to control the pest. They are using insecticides, which we have seen to effectively provide immediate control of the pest.” However, these pesticides have environmental and health issues. “It is against this background that we, as plant breeders, felt it was important to develop varieties that are resistant to the pest. It is a more environmentally friendly, less expensive, and more sustainable solution,” explains Matova.
In his research, he evaluated the breeding potential of exotic FAW-resistant donor lines with local lines. He also investigated the resistance response and stability of local cultivars and inbred lines against FAW. 

While working at the Zimbabwean Department of Research and Specialist Services (DR&SS), Matova collaborated with the International Maize and Wheat Improvement Center (CIMMYT), the University of Zimbabwe, the UFS, and the IAEA to look into the possibility of using mutation breeding in maize crop improvement, with the intention to enhance FAW-resistance in maize genotypes.

He introgressed FAW resistance into the elite breeding materials at both DR&SS and Mukushi Seeds, where he is currently working. Matova believes that although FAW resistance is currently a nice-to-have trait, going forward, all maize varieties released should have a baseline resistance to FAW.

Ultimately, his work generated important information that can guide research and maize breeding for FAW resistance in Southern Africa. All this information is free for researchers to use for the betterment of Africa and the world.

Inspired by greatness

There are a number of people in the industry and academia who have inspired Matova. The list includes Dr Cosmos Magorokosho (CIMMYT), Prof Hussein Shimelis (University of KwaZulu-Natal), Dr Fatma Sarsu (IAEA), Dr Marilyn Warburton (Agricultural Research Service in the United States Department of Agriculture), Dr Amsal Terekegne (ZAMSEED), and Dr John MacRobert (Mukushi Seeds). They all contributed in one way or another to influence Matova in a positive way towards becoming the passionate scientist he is today.

Besides this list of prominent names, Matova says that he was more recently also motivated and encouraged by his PhD supervisor and mentor, Prof Maryke Labuschagne, Professor in Plant Sciences at the UFS. “She is a very special person doing a wonderful job. Prof Labuschagne is kind, thorough, hardworking, and a good mentor,” he states.

Prof Labuschagne is very proud of Matova for receiving this award. “He has been working really hard, and this is a wonderful recognition of the time and effort that he has invested in his research,” she says.


News Archive

UFS study on cell development in top international science journal
2008-09-16

A study from the University of the Free State (UFS) on how the change in the packaging of DNA with cell development influenced the expression of genes, will be published in this week’s early edition of the prestigious international, peer-reviewed science journal, the Proceeding of the National Academy of Sciences of the USA (PNAS).

The PNAS journal has an impact factor of 10, which means that studies published in the journal are, on average, referred to by ten other scientific studies in a two year period. The South African Journal of Science, by comparison, has an impact factor of 0.7.

The UFS study, funded by the Wellcome Trust and the National Research Foundation (NRF), looked at how the change in the packaging of DNA with cell development influenced the expression of genes. It is very relevant to research on stem cells, an area of medicine that studies the possible use of undifferentiated cells to replace damaged tissue.

Prof. Hugh Patterton, of the Department of Microbial, Biochemical and Food Biotechnology at the UFS, who led the study, said: "We are extremely proud of this study. It was conceived in South Africa, it was performed in South Africa, the data were analysed in South Africa, and it was published from South Africa."

When a gene is expressed, the information encoded in the gene is used to manufacture a specific protein. In eukaryotes, which include humans, there is approximately 1m of DNA, containing the genes, in every cell. This length of DNA has to fit into a cell nucleus with a diameter of only about 10 micrometer. In order to fit the DNA into such a small volume, eukaryotic cells wrap their DNA onto successive protein balls, termed nucleosomes. Strings of nucleosomes, resembling a bead of pearls, is folded into a helix to form a chromatin fiber. The study from the UFS investigated how the binding of a specific protein, termed a linker histone, that binds to the length of DNA between nucleosomes, influenced the formation of the chromatin fiber and also the activity of genes.

"We found that the linker histone bound to chromatin in yeast, which we use as a model eukaryote, under conditions where virtually all the genes in the organism were inactive. It was widely believed that the binding of the linker histone caused the inactivation of genes. We studied the relationship between the amount of linker histone bound in the vicinity of each gene and the expression of that gene for all the genes in yeast, using genomic techniques. We made the surprising discovery that even through the linker histone preferentially bound to genes under conditions where the genes were shut off, this inactivation of genes was not caused by the binding of the linker histone and folding of the chromatin,” said Prof. Patterton.

He said: “Instead our data strongly suggested that the observed anti-correlation was due to the movement of enzymes along the DNA molecule, involved in processing the information in genes for the eventual manufacture of proteins. This movement of enzymes displaced the linker histones from the DNA. This finding now requires a rethink on aspects of how packaging of DNA influences gene activity."

Prof. Patterton said that his research group, using the Facility for Genomics and Proteomics as well as the Bioinformatics Node at the UFS, was currently busy with follow-up studies to understand how other proteins in nucleosomes affected the activities of genes, as well as with projects to understand how chemicals found in red wine and in green tea extended lifespan. "We are certainly having a marvelous time trying to understand the fundamental mechanisms of life, and the UFS is an exciting place to be if one was interested in studying life at the level of molecules," he said.


Media Release
Issued by: Lacea Loader
Assistant Director: Media Liaison
Tel: 051 401 2584
Cell: 083 645 2454
E-mail: loaderl.stg@ufs.ac.za  
18 September 2008
 

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