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14 September 2021 | Story Leonie Bolleurs | Photo Supplied
Ofhani Mavhungu, Carina le Roux, Dr Foch de Witt , and Andries van der Merwe.

The Department of Animal Science at the University of the Free State (UFS) walked away with numerous awards at the 52nd congress of the South African Society for Animal Science (SASAS).

Dr Foch de Witt, Senior Lecturer in the department, explains that the SASAS congress is an annual event where scientists, academics, students, and various industry role players come together to share the latest research findings regarding different aspects of animal science and production. 

Acknowledging greatness

The SASAS Gold Medal was awarded to Prof Michiel Scholtz, affiliated professor in the department. “He was presented with this award for his honourable lifelong service to animal science. His scientific contributions and achievements have been recognised as exceptionally meritorious by both national and international animal scientists,” says Prof Frikkie Neser, Head of the Department of Animal Science.

Andries van der Merwe, a postgraduate student, received the SASAS Student Postgraduate Merit Award. According to Prof Neser, this is an annual national merit award to postgraduate students for exceptional academic achievement in Animal Science during undergraduate studies at any South African university.

Dr Sinobongo Mdyogolo, a PhD student of Prof Neser, was presented with the SASAS Bronze Medal in respect of her PhD achievements in the research and technology transfer categories. This is the highest honour a student can get after completion of their PhD degree.

During the SASAS congress, a total of 22 oral and poster contributions were delivered by staff and students from the Department of Animal Science.

A great networking opportunity 

Another highlight for the department was when three of its students – Carina le Roux, Ofhani Mavhungu, and Andries van der Merwe – participated in and won the SASAS national student quiz. Team UFS was one of 13 student teams from various tertiary institutions participating in the competition. The external panel of judges complemented the team on how they integrated theoretical principles in a practical and applied manner.

According to Dr De Witt, UFS Animal Science graduates compare very favourably with other students from tertiary institutions in South Africa. “Many of our students seek employment in the animal feed industry and they excel in their professional career development. It is clear that the curriculum updates of the past few years were successful in ensuring that students are able to integrate theoretical and practical concepts in an applied manner – a skill that is sought after in the industry,” he says. 

He also believes that an event such as the SASAS congress is an ideal network opportunity where students can get exposure to congress presentations, while having the opportunity to meet potential employers and/or sponsors.

“The SASAS congress creates a platform for students to measure themselves in terms of scientific development and career preparedness by interacting directly with other students from different tertiary institutions as well as industry members. Exposure to events such as this furthermore prepares them for their professional registration with the South African Council for Natural Scientific Professions (SACNASP),” adds Dr De Witt. 

News Archive

UFS study on cell development in top international science journal
2008-09-16

A study from the University of the Free State (UFS) on how the change in the packaging of DNA with cell development influenced the expression of genes, will be published in this week’s early edition of the prestigious international, peer-reviewed science journal, the Proceeding of the National Academy of Sciences of the USA (PNAS).

The PNAS journal has an impact factor of 10, which means that studies published in the journal are, on average, referred to by ten other scientific studies in a two year period. The South African Journal of Science, by comparison, has an impact factor of 0.7.

The UFS study, funded by the Wellcome Trust and the National Research Foundation (NRF), looked at how the change in the packaging of DNA with cell development influenced the expression of genes. It is very relevant to research on stem cells, an area of medicine that studies the possible use of undifferentiated cells to replace damaged tissue.

Prof. Hugh Patterton, of the Department of Microbial, Biochemical and Food Biotechnology at the UFS, who led the study, said: "We are extremely proud of this study. It was conceived in South Africa, it was performed in South Africa, the data were analysed in South Africa, and it was published from South Africa."

When a gene is expressed, the information encoded in the gene is used to manufacture a specific protein. In eukaryotes, which include humans, there is approximately 1m of DNA, containing the genes, in every cell. This length of DNA has to fit into a cell nucleus with a diameter of only about 10 micrometer. In order to fit the DNA into such a small volume, eukaryotic cells wrap their DNA onto successive protein balls, termed nucleosomes. Strings of nucleosomes, resembling a bead of pearls, is folded into a helix to form a chromatin fiber. The study from the UFS investigated how the binding of a specific protein, termed a linker histone, that binds to the length of DNA between nucleosomes, influenced the formation of the chromatin fiber and also the activity of genes.

"We found that the linker histone bound to chromatin in yeast, which we use as a model eukaryote, under conditions where virtually all the genes in the organism were inactive. It was widely believed that the binding of the linker histone caused the inactivation of genes. We studied the relationship between the amount of linker histone bound in the vicinity of each gene and the expression of that gene for all the genes in yeast, using genomic techniques. We made the surprising discovery that even through the linker histone preferentially bound to genes under conditions where the genes were shut off, this inactivation of genes was not caused by the binding of the linker histone and folding of the chromatin,” said Prof. Patterton.

He said: “Instead our data strongly suggested that the observed anti-correlation was due to the movement of enzymes along the DNA molecule, involved in processing the information in genes for the eventual manufacture of proteins. This movement of enzymes displaced the linker histones from the DNA. This finding now requires a rethink on aspects of how packaging of DNA influences gene activity."

Prof. Patterton said that his research group, using the Facility for Genomics and Proteomics as well as the Bioinformatics Node at the UFS, was currently busy with follow-up studies to understand how other proteins in nucleosomes affected the activities of genes, as well as with projects to understand how chemicals found in red wine and in green tea extended lifespan. "We are certainly having a marvelous time trying to understand the fundamental mechanisms of life, and the UFS is an exciting place to be if one was interested in studying life at the level of molecules," he said.


Media Release
Issued by: Lacea Loader
Assistant Director: Media Liaison
Tel: 051 401 2584
Cell: 083 645 2454
E-mail: loaderl.stg@ufs.ac.za  
18 September 2008
 

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