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09 September 2021 | Story Dr Nitha Ramnath

The university of the Free State is pleased to invite you to a lunchtime webinar titled, The impact of political influences on university governance structures
  
The political turmoil that disrupted different regions in South Africa in July 2021 has resulted in a renewed focus on the collective responsibility of higher education institutions to assist in solving the key challenges of poverty, inequality, unemployment, and violence in societies. We believe a specific area that needs to be explored more deeply, is how political complexities influence university governance structures. Join our panel of experts for what promises to be an insightful discussion.

Facilitator:

Vuyo Mvoko
Anchor: SABC

Panel:

Prof Mohamed Saleem Badat
Research Professor: College of Humanities, University of KwaZulu-Natal

Prof Thuli Madonsela
Law Trust Chair, Professor: Social Justice and Law,  Stellenbosch University 

Prof Chitja Twala
Vice-Dean: Faculty of the Humanities, University of the Free State

Prof Hermann Giliomee
Internationally renowned historian
 
Date: Wednesday, 22 September 2021
Time: 14:30
RSVP: Alicia Pienaar, pienaaran1@ufs.ac.za by 20 September 2021


Biographies of facilitator and speakers:


Mvoko is the anchor of The Watchdog, a prime-time current affairs show that attracts the biggest names in politics and public policy. It airs weekdays 20:00-21:00 on the SABC News channel (404 on the DSTV platform).
A seasoned journalist with almost 30 years of experience, he previously occupied several senior editorial positions, including stints as political editor for broadcasters such as the SABC and ENCA. He has also written columns for publications such as Business Day, Forbes Africa, and The Herald. 

Mvoko holds BA and MA degrees, and as part of the ‘SABC 8’, was the co-recipient of the 2016 Nat Nakasa Award for ‘courageous and fearless journalism’.

Saleem Badat is Research Professor in the College of Humanities, University of KwaZulu-Natal. He is the former vice-chancellor of the university currently known as Rhodes University and was the first chief executive officer of the Council on Higher Education. Between 2014 and 2018, he was the programme director of International Higher Education and Strategic Projects at the Andrew W. Mellon Foundation in New York. 

Saleem’s books include The Forgotten People: Political Banishment under Apartheid, Black Student Politics: Higher Education and Apartheid, and Black Man, You are on Your Own; the co-authored National Policy and a Regional Response in South African Higher Education, and the co-edited Apartheid Education and Popular Struggles in South Africa. His book chapters, journal articles, policy reports, and newspaper opinion pieces concern questions of equity, redress, and social justice in and through universities, and the decolonisation and transformation of universities in colonised societies. 

Prof Thulisile ‘Thuli’ Madonsela is the Law Trust Chair in Social Justice and a Law professor at Stellenbosch University. She is also the founder of the Thuma Foundation, an independent democracy leadership and literacy public benefit organisation, and is a widely published author.
 
A multiple award-winning legal professional with more than 50 national and global awards, and an advocate of the High Court of South Africa, Prof Madonsela served a seven-year term as the Public Protector of South Africa. She is credited for transforming the institution by enhancing its effectiveness in promoting good governance and integrity, and anticorruption in state affairs. Prof Madonsela has a global reputation for integrity, and strongly advocates for fearlessly enforcing accountability and justice in the exercise of public power and the use of public resources. 

Named one of the TIME100 most influential people in the world, Prof Madonsela is one of the drafters of the South African Constitution, and co-architect of several laws that have sought to anchor South Africa’s democracy. Among the laws she has helped draft are the Promotion of Equality and Prevention of Unfair Discrimination Act (PEPUDA), the Employment Equity Act (EEA), and the Recognition of Customary Marriages Act. She is also a co-architect and founding Chairperson of the African Ombudsman Research Centre and is also co-founder and one of the inaugural leaders of the South African Women Lawyers Association (SAWLA). 

Among numerous accolades, Prof Madonsela is a Paul Harris Fellow, recipient of Transparency International’s Integrity Award, the German Africa Prize, and African Anticorruption Crusader Award. She also spent a year at Harvard as an Advanced Leadership Fellow and is a Tallberg Global Leader, among others.


 

Prof Chitja Twala

Prof Chitja Twala is Associate Professor (Department of History) and Vice-Dean (Faculty of the Humanities) at the University of the Free State (UFS). He holds a PhD (History) from the same university. Twala has a substantial publication record on the history of liberation movements. He is the author of eight chapters (co-author of two) in The Road to Democracy in South Africa: Vol. 4 (1970-1990) and the Road to Democracy in South Africa: Vol. 6 (1990-1996), published in 2010, 2013, and 2019 respectively. He is the recipient of a Mellon Foundation grant and a National Institute for the Humanities and Social Sciences (NIHSS) grant.  He had the following visiting/research fellowships: Harvard University (USA); Kwame Nkrumah Chair in the Institute of African Studies at the University of Ghana (Accra); and the University of California, Los Angeles (USA).
Hermann Giliomee was born in Sterkstroom in 1938 and grew up in the Western Cape. He first taught History at Stellenbosch University and then Political Studies at the University of Cape Town. He has been a visiting fellow at Yale University, the University of Cambridge, and the Woodrow Wilson Centre in Washington DC. He has often published opinion pieces in South African newspapers. He is married to Annette van Coller. 

News Archive

UFS study on cell development in top international science journal
2008-09-16

A study from the University of the Free State (UFS) on how the change in the packaging of DNA with cell development influenced the expression of genes, will be published in this week’s early edition of the prestigious international, peer-reviewed science journal, the Proceeding of the National Academy of Sciences of the USA (PNAS).

The PNAS journal has an impact factor of 10, which means that studies published in the journal are, on average, referred to by ten other scientific studies in a two year period. The South African Journal of Science, by comparison, has an impact factor of 0.7.

The UFS study, funded by the Wellcome Trust and the National Research Foundation (NRF), looked at how the change in the packaging of DNA with cell development influenced the expression of genes. It is very relevant to research on stem cells, an area of medicine that studies the possible use of undifferentiated cells to replace damaged tissue.

Prof. Hugh Patterton, of the Department of Microbial, Biochemical and Food Biotechnology at the UFS, who led the study, said: "We are extremely proud of this study. It was conceived in South Africa, it was performed in South Africa, the data were analysed in South Africa, and it was published from South Africa."

When a gene is expressed, the information encoded in the gene is used to manufacture a specific protein. In eukaryotes, which include humans, there is approximately 1m of DNA, containing the genes, in every cell. This length of DNA has to fit into a cell nucleus with a diameter of only about 10 micrometer. In order to fit the DNA into such a small volume, eukaryotic cells wrap their DNA onto successive protein balls, termed nucleosomes. Strings of nucleosomes, resembling a bead of pearls, is folded into a helix to form a chromatin fiber. The study from the UFS investigated how the binding of a specific protein, termed a linker histone, that binds to the length of DNA between nucleosomes, influenced the formation of the chromatin fiber and also the activity of genes.

"We found that the linker histone bound to chromatin in yeast, which we use as a model eukaryote, under conditions where virtually all the genes in the organism were inactive. It was widely believed that the binding of the linker histone caused the inactivation of genes. We studied the relationship between the amount of linker histone bound in the vicinity of each gene and the expression of that gene for all the genes in yeast, using genomic techniques. We made the surprising discovery that even through the linker histone preferentially bound to genes under conditions where the genes were shut off, this inactivation of genes was not caused by the binding of the linker histone and folding of the chromatin,” said Prof. Patterton.

He said: “Instead our data strongly suggested that the observed anti-correlation was due to the movement of enzymes along the DNA molecule, involved in processing the information in genes for the eventual manufacture of proteins. This movement of enzymes displaced the linker histones from the DNA. This finding now requires a rethink on aspects of how packaging of DNA influences gene activity."

Prof. Patterton said that his research group, using the Facility for Genomics and Proteomics as well as the Bioinformatics Node at the UFS, was currently busy with follow-up studies to understand how other proteins in nucleosomes affected the activities of genes, as well as with projects to understand how chemicals found in red wine and in green tea extended lifespan. "We are certainly having a marvelous time trying to understand the fundamental mechanisms of life, and the UFS is an exciting place to be if one was interested in studying life at the level of molecules," he said.


Media Release
Issued by: Lacea Loader
Assistant Director: Media Liaison
Tel: 051 401 2584
Cell: 083 645 2454
E-mail: loaderl.stg@ufs.ac.za  
18 September 2008
 

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