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09 September 2021 | Story Dr Nitha Ramnath

The university of the Free State is pleased to invite you to a lunchtime webinar titled, The impact of political influences on university governance structures
  
The political turmoil that disrupted different regions in South Africa in July 2021 has resulted in a renewed focus on the collective responsibility of higher education institutions to assist in solving the key challenges of poverty, inequality, unemployment, and violence in societies. We believe a specific area that needs to be explored more deeply, is how political complexities influence university governance structures. Join our panel of experts for what promises to be an insightful discussion.

Facilitator:

Vuyo Mvoko
Anchor: SABC

Panel:

Prof Mohamed Saleem Badat
Research Professor: College of Humanities, University of KwaZulu-Natal

Prof Thuli Madonsela
Law Trust Chair, Professor: Social Justice and Law,  Stellenbosch University 

Prof Chitja Twala
Vice-Dean: Faculty of the Humanities, University of the Free State

Prof Hermann Giliomee
Internationally renowned historian
 
Date: Wednesday, 22 September 2021
Time: 14:30
RSVP: Alicia Pienaar, pienaaran1@ufs.ac.za by 20 September 2021


Biographies of facilitator and speakers:


Mvoko is the anchor of The Watchdog, a prime-time current affairs show that attracts the biggest names in politics and public policy. It airs weekdays 20:00-21:00 on the SABC News channel (404 on the DSTV platform).
A seasoned journalist with almost 30 years of experience, he previously occupied several senior editorial positions, including stints as political editor for broadcasters such as the SABC and ENCA. He has also written columns for publications such as Business Day, Forbes Africa, and The Herald. 

Mvoko holds BA and MA degrees, and as part of the ‘SABC 8’, was the co-recipient of the 2016 Nat Nakasa Award for ‘courageous and fearless journalism’.

Saleem Badat is Research Professor in the College of Humanities, University of KwaZulu-Natal. He is the former vice-chancellor of the university currently known as Rhodes University and was the first chief executive officer of the Council on Higher Education. Between 2014 and 2018, he was the programme director of International Higher Education and Strategic Projects at the Andrew W. Mellon Foundation in New York. 

Saleem’s books include The Forgotten People: Political Banishment under Apartheid, Black Student Politics: Higher Education and Apartheid, and Black Man, You are on Your Own; the co-authored National Policy and a Regional Response in South African Higher Education, and the co-edited Apartheid Education and Popular Struggles in South Africa. His book chapters, journal articles, policy reports, and newspaper opinion pieces concern questions of equity, redress, and social justice in and through universities, and the decolonisation and transformation of universities in colonised societies. 

Prof Thulisile ‘Thuli’ Madonsela is the Law Trust Chair in Social Justice and a Law professor at Stellenbosch University. She is also the founder of the Thuma Foundation, an independent democracy leadership and literacy public benefit organisation, and is a widely published author.
 
A multiple award-winning legal professional with more than 50 national and global awards, and an advocate of the High Court of South Africa, Prof Madonsela served a seven-year term as the Public Protector of South Africa. She is credited for transforming the institution by enhancing its effectiveness in promoting good governance and integrity, and anticorruption in state affairs. Prof Madonsela has a global reputation for integrity, and strongly advocates for fearlessly enforcing accountability and justice in the exercise of public power and the use of public resources. 

Named one of the TIME100 most influential people in the world, Prof Madonsela is one of the drafters of the South African Constitution, and co-architect of several laws that have sought to anchor South Africa’s democracy. Among the laws she has helped draft are the Promotion of Equality and Prevention of Unfair Discrimination Act (PEPUDA), the Employment Equity Act (EEA), and the Recognition of Customary Marriages Act. She is also a co-architect and founding Chairperson of the African Ombudsman Research Centre and is also co-founder and one of the inaugural leaders of the South African Women Lawyers Association (SAWLA). 

Among numerous accolades, Prof Madonsela is a Paul Harris Fellow, recipient of Transparency International’s Integrity Award, the German Africa Prize, and African Anticorruption Crusader Award. She also spent a year at Harvard as an Advanced Leadership Fellow and is a Tallberg Global Leader, among others.


 

Prof Chitja Twala

Prof Chitja Twala is Associate Professor (Department of History) and Vice-Dean (Faculty of the Humanities) at the University of the Free State (UFS). He holds a PhD (History) from the same university. Twala has a substantial publication record on the history of liberation movements. He is the author of eight chapters (co-author of two) in The Road to Democracy in South Africa: Vol. 4 (1970-1990) and the Road to Democracy in South Africa: Vol. 6 (1990-1996), published in 2010, 2013, and 2019 respectively. He is the recipient of a Mellon Foundation grant and a National Institute for the Humanities and Social Sciences (NIHSS) grant.  He had the following visiting/research fellowships: Harvard University (USA); Kwame Nkrumah Chair in the Institute of African Studies at the University of Ghana (Accra); and the University of California, Los Angeles (USA).
Hermann Giliomee was born in Sterkstroom in 1938 and grew up in the Western Cape. He first taught History at Stellenbosch University and then Political Studies at the University of Cape Town. He has been a visiting fellow at Yale University, the University of Cambridge, and the Woodrow Wilson Centre in Washington DC. He has often published opinion pieces in South African newspapers. He is married to Annette van Coller. 

News Archive

Research contributes to improving quality of life for cancer patients
2016-11-21

Description: Inorganic Chemistry supervisors  Tags: Inorganic Chemistry supervisors

Inorganic Chemistry supervisors in the Radiopharmacy
Laboratory during the preparation of a typical complex
mixture to see how fast it reacts. Here are, from the left,
front: Dr Marietjie Schutte-Smith, Dr Alice Brink
(both scholars from the UFS Prestige
Scholar Programme), and Dr Truidie Venter (all three
are Thuthuka-funded researchers).
Back: Prof André Roodt and Dr Johan Venter.
Photo: Supplied

Imagine that you have been diagnosed with bone cancer and only have six months to live. You are in a wheelchair because the pain in your legs is so immense that you can’t walk anymore – similar to a mechanism eating your bones from the inside.

You are lucky though, since you could be injected with a drug to control the pain so effective that you will be able to get out of the wheelchair within a day-and-a-half and be able to walk again. Real-life incidents like these provide intense job satisfaction to Prof André Roodt, Head of Inorganic Chemistry at the University of the Free State (UFS). The research, which is conducted by the Inorganic Group at the UFS, contributes greatly to the availability of pain therapy that does not involve drugs, but improves the quality of life for cancer patients.

The research conducted by the Inorganic Group under the leadership of Prof Roodt, plays a major role in the clever design of model medicines to better detect and treat cancer.

The Department of Chemistry is one of approximately 10 institutions worldwide that conducts research on chemical mechanisms to identify and control cancer. “The fact that we are able to cooperate with the Departments of Nuclear Medicine and Medical Physics at the UFS, the Animal Research Centre, and other collaborators in South Africa and abroad, but especially the methodology we utilise to conduct research (studying the chemical manner in which drugs are absorbed in cancer as well as the time involved), enhances the possibility of making a contribution to cancer research,” says Prof Roodt.

Technique to detect cancer spots on bone
According to the professor, there are various ways of detecting cancer in the body. Cancer can, inter alia, be identified by analysing blood, X-rays (external) or through an internal technique where the patient is injected with a radioactive isotope.

Prof Roodt explains: “The doctor suspects that the patient has bone cancer and injects the person with a drug consisting of an isotope (only emits X-rays and does no damage to tissue) that is connected to a phosphonate (similar to those used for osteoporosis). Once the drug is injected, the isotope (Technetium-99m) moves to the spot on the bone where the cancer is located. The gamma rays in the isotope illuminate the area and the doctor can see exactly where treatment should be applied. The Technetium-99m has the same intensity gamma rays as normal X-rays and therefore operates the same as an internal X-ray supply.” With this technique, the doctor can see where the cancer spots are within a few hours.

The same technique can be used to identify inactive parts of the brain in Alzheimer patients, as well as areas of the heart where there is no blood supply or where the heart muscle is dead.

Therapeutic irradiation of cancer
For the treatment of pain connected with cancer, the isotope Rhenium-186 is injected. Similar to the manner in which the Technetium-99m phosphonate compound is ingested into the body, the Rhenium-186 phosphonate travels to the cancer spots. Patients thus receive therapeutic irradiation – a technique known as palliative therapy, which is excellent for treating pain. A dosage of this therapy usually lasts for about two months.

The therapy is, however, patient specific. The dosages should correspond with the occurrence and size of cancer spots in the patient’s body. First, the location of the cancer will be determined by means of a technetium scan. After that, the size of the area where the cancer occurs has to be determined. The dosage for addressing total pain distribution will be calculated according to these results.

Technique to detect cancer spots on soft tissue
Another technique to detect cancer as spots on bone or in soft tissue and organs throughout the body is by utilising a different type of irradiation, a so-called PET isotope. The Fluor-18 isotope is currently used widely, and in Pretoria a machine called a cyclotron was produced by Dr Gerdus Kemp, who is a former PhD graduate from the Inorganic Research Group. The F-18 is then hidden within a glucose molecule and a patient will be injected with the drug after being tranquillised and after the metabolism has been lowered considerably. The glucose, which is the ‘food' that cancer needs to grow, will then travel directly to the cancer area and the specific area where the cancer is located will thus be traced and ‘illuminated’ by the Fluor-18, which emits its own 'X-rays'.

In the late 80s, Prof Roodt did his own postdoctoral study on this research in the US. He started collaborating with the Department of Nuclear Medicine at the UFS in the early 90s, when he initiated testing for this research.

Through their research of more than 15 years, the Inorganic Group in the Department of Chemistry has made a major contribution to cancer research. Research on mechanisms for the detection of cancer, by designing new clever chemical agents, and the chemical ways in which these agents are taken up in the body, especially contributes to the development in terms of cancer therapy and imaging, and has been used by a number of hospitals in South Africa.

The future holds great promise
Prof Roodt and his team are already working on a bilateral study between the UFS and Kenya. It involves the linking of radio isotopes, as mentioned above, to known natural products (such as rooibos tea), which possess anti-cancer qualities.

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