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28 April 2022
Seminar on Open Science

Publishing academic content behind a paywall not only limits access to scholarly work, but also prevents research output from being visible and making maximum impact. Researchers are paying to publish their research output, and libraries are paying to access it in what is known as double-dipping by publishers, leading to what we term ‘serial crisis’. Research institutions pay twice and still do not see their research widely available to be read.

By signing the Berlin Declaration on Open Access in 2012, the University of the Free State (UFS) committed itself to supporting open access to its research outputs. National initiatives by research institutions and the government make research outputs freely available via national site licensing. The UFS supports this initiative via the South African National Library and Information Consortium (SANLiC) as an interim transformative agreement with publishers, allowing research outputs to be open access, without the additional publication charges.

What do we do about publishers who are unwilling to transform? Do we still pay their massive subscription and publication fees? What do we need to do to ensure that all UFS research outputs are accessible to all?

Topic: Should the UFS continue to subscribe to academic journals that are behind a paywall?
Thursday 12 May 2022
12:00-13:30

Microsoft Teams
RSVP: Elma Viljoen, viljoene@ufs.ac.za (link will be provided)

Join the following top experts for what promises to be an insightful discussion:

  • Colleen Campbell
    Coordinator: Open Access 2020 Initiative
    Max Planck Digital Library, Munich, Germany
  • Ellen Tise
    Senior Director: Library and Information Services, Stellenbosch University

  • Glenn Truran
    Director: South African National Library and Information Consortium (SANLiC)

The welcoming and introduction to the webinar will be conducted by Prof Corli Witthuhn, Vice-Rector: Research.  

Bios of speakers

Colleen Campbell leads external engagement in the open access transition at the Max Planck Digital Library (MPDL) in Munich, Germany. There, she coordinates the Open Access 2020 Initiative, a global alliance of research organisations and their libraries that are driving the transition of today’s scholarly journals to open-access publishing models, and the ESAC Initiative, an international community of practice dedicated to optimising open-access workflows and processes. She is a member of the LIBER Open Access Working Group, serves on the Managing Board of EIFL, a not-for-profit organisation that works with libraries to enable access to knowledge in developing and transition economy countries in Africa, Asia-Pacific, Europe, and Latin America, and contributes to the advisory groups of a number of other scholarly communication initiatives.

Ellen Tise has been the Senior Director of Library and Information Services at Stellenbosch University (SU) since January 2006. She previously held the positions of University Librarian at the University of the Western Cape (UWC) and Deputy University Librarian at the University of the Witwatersrand. She holds a BBibl Honours degree from the UWC and an MPhil in Science and Technology Studies from SU. Among other notable leadership roles, Ms Tise served as the first President of the Library and Information Association of South Africa (LIASA) from 1998 to 2002, and President of the International Federation of Library Associations and Institutions, known as IFLA, for the years 2009 through 2011. She also served as Chair of the Board of the National Library of South Africa (2012-2015), and on the OCLC Board of Trustees (2014-2018). She has just started a second two-year term as Chair of the Freedom of Access to Information and Freedom of Expression Advisory Committee of IFLA. She is the recipient of several awards for distinguished leadership and outstanding contributions to librarianship, including honorary membership of LIASA and an honorary IFLA fellowship. She has published various articles in professional journals and is a regular speaker at national and international conferences, seminars, symposia, etc.

Glenn Truran has been the Director of the South African National Library and Information Consortium (SANLiC) since 2014 and works from home in Cape Town. After graduating from the University of the Witwatersrand (Wits) with a BA and HDipEd (PG), he worked briefly as an educator in South Africa and England. Subsequently, he completed a diploma in Public Policy and Development Administration at Wits and received his MBA from the University of Cape Town in 2003. Before joining SANLiC, he worked in several educational and poverty alleviation non-profit organisations in Gauteng and Cape Town. He has been actively involved in SANLiC’s Open Access Transformational Agreements task team.

Charlie Molepo has been the Deputy Director at the UFS Sasol Library responsible for Research and Scholarly Communications since 2015. He represents the non-academic staff on the University Council and serves on its Finance and Human Resources Committees. Before joining the UFS, he worked at Vista University, the University of Natal, the University of Johannesburg, the University of KwaZulu-Natal Libraries, and Dawson Books UK (Betrams) as the International Account Director for Africa. He serves as President-Elect (2022-2023) in the Library and Information Association of South Africa (LIASA).

News Archive

UFS study on cell development in top international science journal
2008-09-16

A study from the University of the Free State (UFS) on how the change in the packaging of DNA with cell development influenced the expression of genes, will be published in this week’s early edition of the prestigious international, peer-reviewed science journal, the Proceeding of the National Academy of Sciences of the USA (PNAS).

The PNAS journal has an impact factor of 10, which means that studies published in the journal are, on average, referred to by ten other scientific studies in a two year period. The South African Journal of Science, by comparison, has an impact factor of 0.7.

The UFS study, funded by the Wellcome Trust and the National Research Foundation (NRF), looked at how the change in the packaging of DNA with cell development influenced the expression of genes. It is very relevant to research on stem cells, an area of medicine that studies the possible use of undifferentiated cells to replace damaged tissue.

Prof. Hugh Patterton, of the Department of Microbial, Biochemical and Food Biotechnology at the UFS, who led the study, said: "We are extremely proud of this study. It was conceived in South Africa, it was performed in South Africa, the data were analysed in South Africa, and it was published from South Africa."

When a gene is expressed, the information encoded in the gene is used to manufacture a specific protein. In eukaryotes, which include humans, there is approximately 1m of DNA, containing the genes, in every cell. This length of DNA has to fit into a cell nucleus with a diameter of only about 10 micrometer. In order to fit the DNA into such a small volume, eukaryotic cells wrap their DNA onto successive protein balls, termed nucleosomes. Strings of nucleosomes, resembling a bead of pearls, is folded into a helix to form a chromatin fiber. The study from the UFS investigated how the binding of a specific protein, termed a linker histone, that binds to the length of DNA between nucleosomes, influenced the formation of the chromatin fiber and also the activity of genes.

"We found that the linker histone bound to chromatin in yeast, which we use as a model eukaryote, under conditions where virtually all the genes in the organism were inactive. It was widely believed that the binding of the linker histone caused the inactivation of genes. We studied the relationship between the amount of linker histone bound in the vicinity of each gene and the expression of that gene for all the genes in yeast, using genomic techniques. We made the surprising discovery that even through the linker histone preferentially bound to genes under conditions where the genes were shut off, this inactivation of genes was not caused by the binding of the linker histone and folding of the chromatin,” said Prof. Patterton.

He said: “Instead our data strongly suggested that the observed anti-correlation was due to the movement of enzymes along the DNA molecule, involved in processing the information in genes for the eventual manufacture of proteins. This movement of enzymes displaced the linker histones from the DNA. This finding now requires a rethink on aspects of how packaging of DNA influences gene activity."

Prof. Patterton said that his research group, using the Facility for Genomics and Proteomics as well as the Bioinformatics Node at the UFS, was currently busy with follow-up studies to understand how other proteins in nucleosomes affected the activities of genes, as well as with projects to understand how chemicals found in red wine and in green tea extended lifespan. "We are certainly having a marvelous time trying to understand the fundamental mechanisms of life, and the UFS is an exciting place to be if one was interested in studying life at the level of molecules," he said.


Media Release
Issued by: Lacea Loader
Assistant Director: Media Liaison
Tel: 051 401 2584
Cell: 083 645 2454
E-mail: loaderl.stg@ufs.ac.za  
18 September 2008
 

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