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17 August 2022 | Story Samkelo Fetile | Photo Charl Devenish
Gadija Brown MEC for Finance in the Free State
Gadija Brown, Free State MEC for Finance.

Students in the Department of Business Management within the Faculty of Economic and Management Sciences at the University of the Free State (UFS) had the opportunity to attend guest lectures by Gadija Brown, MEC for Finance, and Makalo Mohale, MEC for Economic, Small Business Development, Tourism, and Environmental Affairs (DESTEA) in the Free State government. The guest lectures, which took place on 1 August 2022, were also attended by the Black Management Forum (BMF) Free State Chapter Chair, Mosebetsi Dladla. 

Insights from the guest lecturers

“A priority for the government was SMEs involved in agriculture, tourism, and agricultural industrialisation or manufacturing, as these were the main contributors to the Free State’s economy,” said Brown in her keynote address as she profiled the small business sector of the Free State. 
Makalo Mohale discussed the importance of establishing an enabling environment for the creation of SMEs in the province. “University students, such as the UFS students, can be active participants in the economy by creating businesses that are feasible and viable in order to reduce the unemployment rate of the country, as well as provide employment for themselves,” he said.

Prof Brownhilder Neneh, Head of the Department of Business Management, extended her gratitude to the Free State government representatives for honouring the invitation. She advocated for more interactions and partnerships between the university and provincial government to create a synergy of collaborations between government and academia.

Makalo Mohale MEC Economic, Small Business Development, Tourism, and Environmental Affairs
Makalo Mohale. Photo: Supplied. 


From sit-down exam to practical engagement

The Department of Business Management offers Small Business Management as an undergraduate programme at NQF Level 7 (16 credits) during the third year of study. The module's goal is to give students the knowledge and abilities they need to become capable and self-assured business professionals or leaders.
Dr Ekaete Benedict, Coordinator of the Entrepreneurship and Small Business Management modules, outlined that the group project is what students are assessed on, instead of a sit-down examination. 

“One of the first things I did to change the curricula of the module was to apply for it to become a continuous assessment module,” she said.  “That is, do away with the sit down and write exam component at the end of the semester, and rather test the students on practical engagement with real-life business scenarios and people throughout the duration of the semester,” she continued. 

“This is in line with best practices at the world's top universities,” Dr Benedict concluded.

News Archive

Nuclear Medicine on the forefront of cancer research
2017-07-10

Description: Nuclear Medicine on the forefront of cancer research Tags: Nuclear Medicine, cancer research, Dr Je’nine Horn-Lodewyk’s, tumour detection method, cancer, Department of Nuclear Medicine 

Dr Je’nine Horn-Lodewyk’s tumour detection method
could be the cost-effective breakthrough needed to decrease
the mortality rate in breast cancer patients.
Photo: Anja Aucamp

The field of Nuclear Medicine in South Africa and the rest of the world are expanding rapidly due to the development of hybrid cameras and new radiopharmaceuticals. These developments have a huge impact on the diagnosis and therapy of cancer.

The most advanced of these cameras, Positron emission tomography combined with normal CTs (PETCT), are not yet widely available in South Africa due to the cost of the cameras and the radiopharmaceuticals. A more cost-effective alternative can be of great benefit. To achieve this, the focus should be on developing new radiopharmaceuticals that can be used with the current cost-effective gamma cameras, according to University of the Free State researcher, Dr Je’nine Horn-Lodewyk from the Department of Nuclear Medicine.

Fluorodeoxyglucose (18F-FDG), a radiolabelled glucose analogue, is currently the radiopharmaceutical most commonly used in PET/CT imaging for mainly oncology indications. Although it is considered the gold standard for imaging in several malignancies, it does have certain disadvantages. An 18F-FDG PET/CT diagnostic imaging study can cost between R25 000 and R35 000 for a single patient in the private sector. The 18F-FDG is also more radioactive, which requires much stricter handling and shielding to avoid high radiation dosages to staff and patients.

Successful research potential innovative solution
In the search for the ideal radiopharmaceutical for tumour detection, the South African National Nuclear Energy Corporation (Necsa) developed a local synthesis process for ethylenedicysteine-deoxyglucose (EC-DG). EC-DG is also a glucose analogue similar to FDG. They succeeded in labelling the compound with Technetium-99-metastable-pertechnetate (99mTcO4-), the most common nuclear medicine isotope used for approximately 95% of nuclear medicine procedures, creating 99mTc-EC-DG.

In partnership with Dr Horn-Lodewyk, this compound was successfully used in various animal models and clinical scenarios, resulting in approval by the Medicine Control Council to use it in a human study. Research is also planned in order to investigate diagnostic accuracy in other cancers like lymphoma.  The end result of this research can produce a radiopharmaceutical that is cost effective, does not require the use of costly specialised equipment, has no significant side-effects, no special patient preparation, renders late imaging possible, and has decreased radiation risks.

Dr Horn-Lodewyk is grateful for the support of her mentor, Prof Anton Otto, as well as Dr Gert Engelbrecht, Head of the Department of Nuclear Medicine, Prof Jan Rijn Zeevaart from North-West University’s Preclinical Drug Development Platform and Necsa, and Judith Wagener from Necsa. This innovative research would also not have been possible without the financial assistance of Dr Glen Taylor and Eleanor van der Westhuizen in the Directorate of Research Development.

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