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11 August 2022 | Story NONSINDISO QWABE | Photo SUPPLIED
The erudite watchmaker, Jabulani Mabuza.

At a time when it is becoming fashionable for high-tech smartwatches and fitness gadgets to adorn your wrist, there will always be room for a classic timepiece. Wristwatches in particular tell a different story to people of all social classes, and for Qwaqwa student Jabulani Mabuza, the process of making different watches to suit different tastes is what excites him the most.

Mabuza is in his final year of a BCom General Management degree.  In January 2020, he acted on his curiosity about the process of assembling a watch, and subsequently registered his watch business, Honour Watches, in January 2021.
Since then, he has steadily honed his craft, learning more about the art of watches. He recently made it through to the central regional rounds of the Entrepreneurship Development in Higher Education (EDHE) competition in the Existing Businesses category for studentpreneurs. 

On the pursuit of mastering the art of watchmaking

Horology is the study and measurement of time. It is the process of allowing yourself the time and patience required to master the art of building a watch from scratch, and Mabuza said he enjoyed the intricacies of the watchmaking process. “What I enjoy about horology is learning the deeper technicalities of the art, the whole process – from understanding basic astronomy and how planets move in our solar system, to sort of emulating that in a watch mechanism. The working of metals transformed into watch components that actually tell time, is what I enjoy most and what I am investing in so that I can master it one day,” he said.

As a BCom student, he said his studies have largely influenced his business journey, as it helps him understand the structure of his business professionally. “It assists me with the business administration and management of Honour, and the rest is inspired by my creativity and passion for what time means to human beings.”

Mabuza said South Africa does not have a watchmaking plant as yet, so all the components for his watches are currently imported from Japan and Switzerland. He hopes to one day have his own production plant that will produce watches from scratch, in order to teach more people this skill and to create jobs, for which there is always a need. Currently, he studies the watch components to learn which movement best complements which type of hand and casing, in order to assemble them according to the designs he likes. 

“I enjoy the pursuit of creating a mechanical auto-magnetic watch for international travellers that will automatically adjust to different time zones as they travel. These horological pursuits are what I enjoy the most, believe in, and am passionate about.”

The regional rounds will be held on the UFS Bloemfontein Campus from 19 to 23 September 2022.

News Archive

Nuclear Medicine on the forefront of cancer research
2017-07-10

Description: Nuclear Medicine on the forefront of cancer research Tags: Nuclear Medicine, cancer research, Dr Je’nine Horn-Lodewyk’s, tumour detection method, cancer, Department of Nuclear Medicine 

Dr Je’nine Horn-Lodewyk’s tumour detection method
could be the cost-effective breakthrough needed to decrease
the mortality rate in breast cancer patients.
Photo: Anja Aucamp

The field of Nuclear Medicine in South Africa and the rest of the world are expanding rapidly due to the development of hybrid cameras and new radiopharmaceuticals. These developments have a huge impact on the diagnosis and therapy of cancer.

The most advanced of these cameras, Positron emission tomography combined with normal CTs (PETCT), are not yet widely available in South Africa due to the cost of the cameras and the radiopharmaceuticals. A more cost-effective alternative can be of great benefit. To achieve this, the focus should be on developing new radiopharmaceuticals that can be used with the current cost-effective gamma cameras, according to University of the Free State researcher, Dr Je’nine Horn-Lodewyk from the Department of Nuclear Medicine.

Fluorodeoxyglucose (18F-FDG), a radiolabelled glucose analogue, is currently the radiopharmaceutical most commonly used in PET/CT imaging for mainly oncology indications. Although it is considered the gold standard for imaging in several malignancies, it does have certain disadvantages. An 18F-FDG PET/CT diagnostic imaging study can cost between R25 000 and R35 000 for a single patient in the private sector. The 18F-FDG is also more radioactive, which requires much stricter handling and shielding to avoid high radiation dosages to staff and patients.

Successful research potential innovative solution
In the search for the ideal radiopharmaceutical for tumour detection, the South African National Nuclear Energy Corporation (Necsa) developed a local synthesis process for ethylenedicysteine-deoxyglucose (EC-DG). EC-DG is also a glucose analogue similar to FDG. They succeeded in labelling the compound with Technetium-99-metastable-pertechnetate (99mTcO4-), the most common nuclear medicine isotope used for approximately 95% of nuclear medicine procedures, creating 99mTc-EC-DG.

In partnership with Dr Horn-Lodewyk, this compound was successfully used in various animal models and clinical scenarios, resulting in approval by the Medicine Control Council to use it in a human study. Research is also planned in order to investigate diagnostic accuracy in other cancers like lymphoma.  The end result of this research can produce a radiopharmaceutical that is cost effective, does not require the use of costly specialised equipment, has no significant side-effects, no special patient preparation, renders late imaging possible, and has decreased radiation risks.

Dr Horn-Lodewyk is grateful for the support of her mentor, Prof Anton Otto, as well as Dr Gert Engelbrecht, Head of the Department of Nuclear Medicine, Prof Jan Rijn Zeevaart from North-West University’s Preclinical Drug Development Platform and Necsa, and Judith Wagener from Necsa. This innovative research would also not have been possible without the financial assistance of Dr Glen Taylor and Eleanor van der Westhuizen in the Directorate of Research Development.

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