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02 August 2022 | Story Leonie Bolleurs | Photo Leonie Bolleurs
Alistair Naidoo, second-year master’s student in Conservation Genetics and full-time technician in the Department of Genetics; Prof Paul Grobler, Head of the Department of Genetics; Prof Gordon Luikart; and Hannah Janse van Vuuren, third-year master’s student in Conservation Genetics.

It is an important and exciting time to be doing research in conservation genetics. This is according to Prof Gordon Luikart, Professor of Conservation Ecology and Genetics at the Flathead Lake Bio Station at the University of Montana in the United States. 

Prof Luikart, whose primary research focus is the application of genetics to the conservation of natural and managed populations, recently delivered a lecture, The Expanding Role of Genetics/omics in Wildlife Research and Conservation, on the Bloemfontein Campus of the University of the Free State (UFS). The lecture, hosted by the Department of Genetics, was attended by a group of students and lecturers in conservation and a number of related fields. 

He is one of the leading scientists in the field of conservation genetics, including integration of genomics in conservation projects. He is also co-author of the textbook Conservation and the Genomics of populations – the current prescribed textbook for GENE3744.

Species threatened with extinction

In 2008, the International Union for Conservation of Nature (IUCN) stated that approximately 10-20% of all vertebrate and plant species are threatened with extinction over the next few decades. In 1984, American biologist Edward O Wilson also said that it will take millions of years to correct the ongoing loss of genetics and species diversity caused by the destruction of natural habitats. “This is the folly our descendants are least likely to forgive us.”

Prof Luikart is of the opinion that genetics has enormous potential to help manage wildlife and prevent extirpation. “My research works to realise this potential and help wildlife managers conserve populations and ecosystems,” he says. 

Conservation managers and biologists have understood the risks of inbreeding for more than 100 years. In his lecture, one of the aspects of genetic conservation he focused on, was the negative effects of inbreeding and how this can be reversed using genetic rescue. 

With the genetic rescue study, they found that the gene flow into recently isolated populations can increase individual fitness and population growth. He proposed that conservation managers should consider genetic principles and rescue as practical and important tools. 

Prof Luikart also provided a list of information that can be retrieved from molecular genetic data to help conservation managers. This includes intel on census and effective population size, gene flow and dispersal, local adaptation and selection, forensics, genetic identification and law enforcement, and disease ecology and transmission. 

Non-invasive genetic monitoring

In terms of detecting gene flow, he focused on a study about non-invasive genetic monitoring that was conducted in the Yellowstone Park. Prof Luikart and a group of students collected the shed hair and faeces of the grizzly bear, obtained from trees and hair traps, which were used as a source of DNA. 

They established, for instance, that inbreeding depression is more common and stronger than previously thought in natural populations. Genetic monitoring, using non-invasive methods as described, has been found to be an effective tool that conservation managers should consider for detecting inbreeding and loss of genome-wide variation.

His research on the bighorn sheep, the alpine ibex, and the black bear informed most of the findings he discussed during his lecture.

News Archive

UFS student makes breakthrough in the application of nanorobots
2005-04-21

A student from the University of the Free State (UFS) has made a ground-breaking discovery in the field of microbiology by uncovering a series of new compounds that may in future be used to lubricate man-made nanorobots.

Mr Olihile Sebolai, a full-time student at the UFS’s Department of Microbial- Biochemical and Food Biotechnology, made this discovery while working on his M Sc-study on yeast.

With this discovery Mr Sebolai will also be awarded six prestigious prizes during this week’s autumn graduation ceremony at the UFS.  This university has recognised this exceptional achievement as a build-up to the celebration of national Science and Technology week next month.     

Mr Sebolai’s dissertation on the yeast genus Saccharomycopsis Schionning has been published in an accredited international journal of repute. 

“Words cannot describe how excited I am. I never expected to receive such recognition for my studies.  I am humbled by all of this,” said Mr Sebolai.

The Lipid Biotechnology Group at the UFS recently discovered that some yeasts produce their own water-propelled capsules in which they are transported.  These capsules have different shapes and resemble among others miniature flying saucers, hats with razor sharp brims etc.  “In order to function properly, parts of the capsules are oiled with prehistoric lubricants – lubricants that are produced by yeasts and that probably existed for many millions of years as yeasts developed,” said Mr Sebolai.  

According to Mr Sebolai these capsules are so small that approximately 300 can be fitted into the full-stop at the end of a sentence and are therefore invisible to the naked eye.

“With my studies I discovered many new compounds that resemble these prehistoric lubricants.  These lubricants may in future be used to lubricate man-made nanorobots and are similar in size compared to yeast capsules,” said Mr Sebolai.  The nanorobots are used to perform tasks in places that are invisible to the naked eye and could one day be used, among others, to clean up human arteries.

Mr Sebolai has been interested in the subject of Micro technology since he was at RT Mokgopa High School in Thaba ‘Nchu.  “I was specifically interested in the many possible applications the subject has – in the industry, as well as in medicine,” said Mr Sebolai. 

His next goal is to successfully complete his Ph D-degree.

The prizes that will be awarded to Mr Sebolai this week include:

Best Magister student at the UFS (Senate medal and prize);

Best Magister student in the Faculty of Natural and Agricultural Science and Dean’s medal at the same faculty;

The Andries Brink – Sasol-prize for the best M Sc dissertation in Microbiology;

The JP van der Walt prize for best M Sc dissertation in yeast science;

The Chris Small prize for an outstanding Master’s dissertation; and

Honorary colours awarded by the UFS Student Representative Council

Media release

Issued by:                     Lacea Loader

                                    Media Representative

                                    Tel:  (051) 401-2584

                                    Cell:  083 645 2454

                                    E-mail:  loaderl.stg@mail.uovs.ac.za

20 April 2005

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