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02 August 2022 | Story Leonie Bolleurs | Photo Leonie Bolleurs
Alistair Naidoo, second-year master’s student in Conservation Genetics and full-time technician in the Department of Genetics; Prof Paul Grobler, Head of the Department of Genetics; Prof Gordon Luikart; and Hannah Janse van Vuuren, third-year master’s student in Conservation Genetics.

It is an important and exciting time to be doing research in conservation genetics. This is according to Prof Gordon Luikart, Professor of Conservation Ecology and Genetics at the Flathead Lake Bio Station at the University of Montana in the United States. 

Prof Luikart, whose primary research focus is the application of genetics to the conservation of natural and managed populations, recently delivered a lecture, The Expanding Role of Genetics/omics in Wildlife Research and Conservation, on the Bloemfontein Campus of the University of the Free State (UFS). The lecture, hosted by the Department of Genetics, was attended by a group of students and lecturers in conservation and a number of related fields. 

He is one of the leading scientists in the field of conservation genetics, including integration of genomics in conservation projects. He is also co-author of the textbook Conservation and the Genomics of populations – the current prescribed textbook for GENE3744.

Species threatened with extinction

In 2008, the International Union for Conservation of Nature (IUCN) stated that approximately 10-20% of all vertebrate and plant species are threatened with extinction over the next few decades. In 1984, American biologist Edward O Wilson also said that it will take millions of years to correct the ongoing loss of genetics and species diversity caused by the destruction of natural habitats. “This is the folly our descendants are least likely to forgive us.”

Prof Luikart is of the opinion that genetics has enormous potential to help manage wildlife and prevent extirpation. “My research works to realise this potential and help wildlife managers conserve populations and ecosystems,” he says. 

Conservation managers and biologists have understood the risks of inbreeding for more than 100 years. In his lecture, one of the aspects of genetic conservation he focused on, was the negative effects of inbreeding and how this can be reversed using genetic rescue. 

With the genetic rescue study, they found that the gene flow into recently isolated populations can increase individual fitness and population growth. He proposed that conservation managers should consider genetic principles and rescue as practical and important tools. 

Prof Luikart also provided a list of information that can be retrieved from molecular genetic data to help conservation managers. This includes intel on census and effective population size, gene flow and dispersal, local adaptation and selection, forensics, genetic identification and law enforcement, and disease ecology and transmission. 

Non-invasive genetic monitoring

In terms of detecting gene flow, he focused on a study about non-invasive genetic monitoring that was conducted in the Yellowstone Park. Prof Luikart and a group of students collected the shed hair and faeces of the grizzly bear, obtained from trees and hair traps, which were used as a source of DNA. 

They established, for instance, that inbreeding depression is more common and stronger than previously thought in natural populations. Genetic monitoring, using non-invasive methods as described, has been found to be an effective tool that conservation managers should consider for detecting inbreeding and loss of genome-wide variation.

His research on the bighorn sheep, the alpine ibex, and the black bear informed most of the findings he discussed during his lecture.

News Archive

UFS boasts with world class research apparatus
2005-10-20

 

 

At the launch of the diffractometer were from the left Prof Steve Basson (Chairperson:  Department of Chemistry at the UFS), Prof Jannie Swarts (Unit for Physical and Macro-molecular Chemistry at the UFS Department of Chemistry), Mr Pari Antalis (from the provider of the apparatus - Bruker SA), Prof Herman van Schalkwyk (Dean:  Faculty of Natural and Agricultural Sciences at the UFS), Prof André Roodt (head of the X-ray diffraction unit at the UFS Department of Chemistry) and Prof Teuns Verschoor (Vice-Rector:  Academic Operations at the UFS).

UFS boasts with world class research apparatus
The most advanced single crystal X-ray diffractometer in Africa has been installed in the Department of Chemistry at the University of the Free State (UFS).

“The diffractometer provides an indispensable technique to investigate compounds for medicinal application for example in breast, prostate and related bone cancer identification and therapy, currently synthesized in the Department of Chemistry.  It also includes the area of homogeneous catalysis where new compounds for industrial application are synthesised and characterised and whereby SASOL and even the international petrochemical industry could benefit, especially in the current climate of increased oil prices,” said Prof Andrè Roodt, head of the X-ray diffraction unit at the UFS Department of Chemistry.

The installation of the Bruker Kappa APEX II single crystal diffractometer is part of an innovative programme of the UFS management to continue its competitive research and extend it further internationally.

“The diffractometer is the first milestone of the research funding programme for the Department of Chemistry and we are proud to be the first university in Africa to boast with such advanced apparatus.  We are not standing back for any other university in the world and have already received requests for research agreements from universities such as the University of Cape Town,” said Prof Herman van Schalkwyk, Dean:  Faculty of Natural and Agricultural Sciences at the UFS.

The diffractometer is capable of accurately analysing molecules in crystalline form within a few hours and obtain the precise geometry – that on a sample only the size of a grain of sugar.   It simultaneously gives the exact distance between two atoms, accurate to less than fractions of a billionth of a millimetre.

“It allows us to investigate certain processes in Bloemfontein which has been impossible in the past. We now have a technique locally by which different steps in key chemical reactions can be evaluated much more reliable, even at temperatures as low as minus 170 degrees centigrade,” said Prof Roodt.

A few years ago these analyses would have taken days or even weeks. The Department of Chemistry now has the capability to investigate chemical compounds in Bloemfontein which previously had to be shipped to other, less sophisticate sites in the RSA or overseas (for example Sweden, Russia and Canada) at significant extra costs.

Media release
Issued by:Lacea Loader
Media Representative
Tel:   (051) 401-2584
Cell:  083 645 2454
E-mail:  loaderl.stg@mail.uovs.ac.za
19 October 2005   

 

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