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02 August 2022 | Story Leonie Bolleurs | Photo Leonie Bolleurs
Alistair Naidoo, second-year master’s student in Conservation Genetics and full-time technician in the Department of Genetics; Prof Paul Grobler, Head of the Department of Genetics; Prof Gordon Luikart; and Hannah Janse van Vuuren, third-year master’s student in Conservation Genetics.

It is an important and exciting time to be doing research in conservation genetics. This is according to Prof Gordon Luikart, Professor of Conservation Ecology and Genetics at the Flathead Lake Bio Station at the University of Montana in the United States. 

Prof Luikart, whose primary research focus is the application of genetics to the conservation of natural and managed populations, recently delivered a lecture, The Expanding Role of Genetics/omics in Wildlife Research and Conservation, on the Bloemfontein Campus of the University of the Free State (UFS). The lecture, hosted by the Department of Genetics, was attended by a group of students and lecturers in conservation and a number of related fields. 

He is one of the leading scientists in the field of conservation genetics, including integration of genomics in conservation projects. He is also co-author of the textbook Conservation and the Genomics of populations – the current prescribed textbook for GENE3744.

Species threatened with extinction

In 2008, the International Union for Conservation of Nature (IUCN) stated that approximately 10-20% of all vertebrate and plant species are threatened with extinction over the next few decades. In 1984, American biologist Edward O Wilson also said that it will take millions of years to correct the ongoing loss of genetics and species diversity caused by the destruction of natural habitats. “This is the folly our descendants are least likely to forgive us.”

Prof Luikart is of the opinion that genetics has enormous potential to help manage wildlife and prevent extirpation. “My research works to realise this potential and help wildlife managers conserve populations and ecosystems,” he says. 

Conservation managers and biologists have understood the risks of inbreeding for more than 100 years. In his lecture, one of the aspects of genetic conservation he focused on, was the negative effects of inbreeding and how this can be reversed using genetic rescue. 

With the genetic rescue study, they found that the gene flow into recently isolated populations can increase individual fitness and population growth. He proposed that conservation managers should consider genetic principles and rescue as practical and important tools. 

Prof Luikart also provided a list of information that can be retrieved from molecular genetic data to help conservation managers. This includes intel on census and effective population size, gene flow and dispersal, local adaptation and selection, forensics, genetic identification and law enforcement, and disease ecology and transmission. 

Non-invasive genetic monitoring

In terms of detecting gene flow, he focused on a study about non-invasive genetic monitoring that was conducted in the Yellowstone Park. Prof Luikart and a group of students collected the shed hair and faeces of the grizzly bear, obtained from trees and hair traps, which were used as a source of DNA. 

They established, for instance, that inbreeding depression is more common and stronger than previously thought in natural populations. Genetic monitoring, using non-invasive methods as described, has been found to be an effective tool that conservation managers should consider for detecting inbreeding and loss of genome-wide variation.

His research on the bighorn sheep, the alpine ibex, and the black bear informed most of the findings he discussed during his lecture.

News Archive

Research into surrogate milk important to wildlife conservation
2017-05-08

Description: Prof Garry Osthoff  Tags: Prof Garry Osthoff

Prof Gary Osthoff from the UFS Department of
Microbial, Biochemical and Food Biotechnology,
will soon work on a milk formula for elephants.
Photo: Supplied

Research is being done at the University of the Free State (UFS) to analyse and synthetically imitate the unique milk of various wildlife species. This research is not only of scientific value, but also serves the conservation of South Africa’s wildlife species. At the forefront of this research is Prof Garry Osthoff from the Department of Microbial, Biochemical and Food Biotechnology.

Orphaned rhino calf pulled through with surrogate milk

“There is still a lot of research to be done. Naturally the research is of scientific importance, but with surrogate milk having the same composition as the mother’s milk of a specific species, orphaned calves or cubs of that species could be pulled through during a difficult time of weaning. Bearing in mind that exotic animals fetch thousands and even millions of rands at auctions, it goes without saying a game farmer will do everything possible to provide only the best nourishment to such an orphaned animal. In such a case, synthetically-manufactured milk would be the right choice,” says Prof Osthoff.

The fruits of his research were recently demonstrated in Germany when a rhino calf was left orphaned in the Leipzig Zoo. Prof Osthoff’s article: “Milk composition of a free-ranging white rhinoceros during late lactation” was used as a directive for applying surrogate milk for horse foals (which is already commercially available), since the composition of horse and rhino milk largely corresponds. The surrogate milk was used with great success and the rhino calf is flourishing. He mentions that such an orphan is often given the wrong nourishment with the best intentions, resulting in the starvation of the animal despite the amount of cow’s milk it devours.

With surrogate milk having the same
composition as the mother’s milk of a
specific species, orphaned calves or
cubs of that species could be pulled
through during the difficult time
of weaning.

Milk formula for baby elephants in the pipeline
With baby elephants left orphaned due to the increase in elephant poaching for their ivory, several attempts have been made to create a milk formula in order to feed these elephants. To date, many elephants have died in captivity from side effects such as diarrhoea as a result of the surrogate formula which they were fed.

Prof Osthoff recently received a consignment of frozen milk which he, together with researchers from Zimbabwe, will use to work on a milk formula for elephants. They are studying the milk in a full lactation period of two years. During lactation, the composition of the milk changes to such an extent that a single surrogate formula will not be sufficient. Four different formulas should probably be designed.

Prof Osthoff says that of the different species he has researched, elephants are the most interesting and deviate most from the known species.

Although his research to develop surrogate milk is adding much value to the wildlife industry, and although he finds this part of his work very exciting, his research focus is on food science and nutrition. “What is currently authentic in milk research is the study of the fat globules with content, the structure and composition of the casein micelle, and the prebiotic sugars. The knowledge which is gained helps to improve the processing, development of new food products, and development of food products for health purposes,” says Prof Osthoff.

 

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